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Gastroenterology in the News
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Your search returned 101 results
from the time period: last 30 days.
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Laparoscopic Surgery for T4 Tumor of the Colon Cancer (LST4C Trial) - Full Text View ... The investigators previous study indicated that laparoscopic surgery is feasible in T4 colon cancers with comparable clinical and oncologic outcomes ... the short-and long-term survival outcomes of laparoscopic surgery and conventional open surgery for T4 colon cancer as well as the mortality and the morbidity ...
Oncology (4)
Colonic Neoplasms (4), Neoplasms (2)
2. California combats deadly hepatitis A outbreak  
Date: 10/19/2017 09:14
CNN (United States)
Deadly hepatitis A outbreak in California... already distributed more than 80,000 doses of the hepatitis A vaccine... Somehow, the highly contagious liver infection hepatitis A was introduced into the homeless community... Typically, fewer than 3,000 cases of hepatitis A are reported each year in the United States ... One thing that is very interesting about the hepatitis A virus is that it actually survives in the ...
Infectious Diseases (8), Vaccines (2)
Hepatitis A (7), Infections (1), Communicable Diseases (1)
Liver cancers linked to compound popular in herbal remedies... found in some natural remedies, could be associated with liver cancers... mutations in the genes that predispose an individual to liver cancers... After analyzing the DNA of the liver cancers the team looked into the mutational data from 1,400 liver cancer patients worldwide ...
Oncology (6), Urology (1), Anti-Obesity and Weight Loss (1)
Liver Neoplasms (5), Balkan Nephropathy (1), Neoplasms (1)
Prostate Cancer News
EXACT Sciences : Grand Prize Winners of Packers-Cologuard Colon Cancer Awareness Campaign Announced - Prostate Cancer News Today. EXACT Sciences : Grand Prize Winners of Packers-Cologuard Colon Cancer Awareness Campaign Announced... manufacturer of Cologuard, announced today the four Grand Prize winners of the Green Bay Packers-Cologuard Colon Cancer Awareness Campaign.
Oncology (5)
Colonic Neoplasms (4), Prostatic Neoplasms (1)
BBC News (United Kingdom)
California hepatitis A outbreak death toll climbs to 19... Officials in San Francisco are bracing for the liver disease to spread. The death toll from California's hepatitis A outbreak has reached 19, one week after the ... Hepatitis A, which attacks the liver, is usually spread through ... Diego's drinking water for fecal contamination, which causes the liver disease.
Infectious Diseases (7), Vaccines (1)
Hepatitis A (7), Liver Diseases (2), Jaundice (1)
A Phase Ia/Ib Study of CS1001 in Advanced Solid Tumors - Full Text View... This is a phase Ia/Ib, open-label, multiple-dose, dose-escalation and expansion study to evaluate the safety ... A Phase Ia/Ib, Open-Label, Multiple-Dose, Dose-Escalation and Expansion Study of the Anti-PD ...
Neoplasms (6)
... Functioning of New Antiviral Therapies in Subjects With Chronic Hepatitis HCV-related - Full Text View. Chronic hepatitis HCV-related is the most common cause of chronic liver disease in Italy ... However, in patients with chronic hepatitis C, a high lifetime prevalence of major depressive disorder ... such associations between mood and anxiety disorders and chronic hepatitis C may reflect a high prevalence of bipolar spectrum ...
Immune System Diseases (10), Infectious Diseases (10), Neuroscience (3)
Chronic Hepatitis C (7), Depressive Disorder (4), Chronic Hepatitis (3)
A challenge in pancreatic cancer is that the tumor also cloaks itself in a microenvironment, surrounded by a ... the use of a vitamin D derivative that makes pancreatic tumor cells vulnerable to chemotherapy and more sensitive to the ... announced today seek to address a wide variety of cancers including breast, lung, melanoma, multiple myeloma, ovarian, pancreatic, hypermutant-pediatric cancers, sarcoma, and urothelial cancer ...
Oncology (24)
Neoplasms (19), Pancreatic Neoplasms (8), Multiple Myeloma (1)
CBS News
California declares state of emergency over deadly hepatitis A outbreak... due to a lack of vaccines in a deadly hepatitis A outbreak in several California counties, CBS Los Angeles ... declaration allows the state to "increase its supply of hepatitis A vaccines in order to control the current outbreak ... month declared a public health emergency because of the liver disease outbreak that has killed 16 people and hospitalized 300 ...
Infectious Diseases (8), Vaccines (5)
Hepatitis A (8), Communicable Diseases (1), Liver Diseases (1)
Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers - Full Text View... Markers combining signatures of liver fibrosis and hepatic inflammation from many 'omics technologies. Other Names. Multi-omics markers. Lipidomics. Microbiomics. Genomics. Metagenomics. Metatranscriptomics. Transcriptomics. miRNA-omics. Metabolomics. Proteomics.
Liver Fibrosis (6), Fibrosis (3), Necrosis (1)
Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment - Full Text View... randomized, open label, single dose, parallel cohort, multisite study to investigate the effect of varying degrees of hepatic impairment on the plasma pharmacokinetics (total and unbound) of PF-05221304 after a single oral dose administered ...
Clip Placement Following Colonic Endoscopic Mucosal Resection (EMR) - Full Text View. Study design: A national, multi-center, patient- an assessor-blinded, randomized clinical trial. Study population: Patients undergoing EMR with a moderate to severe risk (right sided colon, ≥2cm) of developing Deylaed Bleeding (DB. Intervention: PC will be compared to standard care (no PC.
Adenoma (1)
The Evans lab's discovery that vitamin D can make pancreatic tumors more susceptible to drug therapy suggested the added potential to also wake up the ... I've been on high-dose vitamin D since my diagnosis of stage 4 pancreatic cancer and I truly feel that it has played an ... Our goal is to completely change the landscape of pancreatic cancer therapy in a really short time.
Oncology (18)
Neoplasms (14), Pancreatic Neoplasms (9), Infections (1)
14. Endoscopic Ultrasound Guided Liver Biopsy  
Date: 10/12/2017 09:50
Endoscopic Ultrasound Guided Liver Biopsy - Full Text View... Endoscopic ultrasound guided liver biopsy (EUS-LB) is proposed as a newer method ... Endoscopic Ultrasound (EUS) provides high resolution images of left lobe of ... obstructive lesion is identified by EUS that will require endoscopic retrograde cholangiopancreatography (ERCP) then it would cost-effective to perform EUS-LB ...
Infections (2), Ascites (1)
Phase Ib/II Study of Durvalumab and Guadecitabine in Advanced Kidney Cancer - Full Text View... Phase Ib: 6-12 subjects; enrolled into either Cohort 1 or 2... Patients from Phase Ib treated at the eventual phase II dose will be combined with patients in Phase II ... Phase Ib Treatment Plan.
Oncology (2)
Kidney Neoplasms (2)
Phase III Study of Simultaneous Integrated Boost Radiotherapy (SIB-IMRT) With or Without Concurrent Chemotherapy for Locally Advanced Esophageal Cancer - 3JECROG-P02 - Full Text View Active Comparator: SIB-IMRT combined chemotherapy followed by chemotherapy SIB-IMRT: Patients receive radiotherapy once daily, 5 days a week for an average of 5.5 weeks. Radiotherapy is delivered to achieve a prophylactic dosage of 50.4Gy to PTV and 59.92Gy to PGTV in 28 fractions, respectively.
Oncology (2)
Esophageal Neoplasms (2)
Ardelyx rises on better IBS data and a clearer path to FDA filing... more positive phase 3 trial for its constipation-predominant irritable bowel syndrome (IBS-c) drug tenapanor, setting up regulatory filings next year ... to impress investors, drawing out unfavorable comparisons with rival IBS-c therapies such as Ironwood Pharma’s already-approved Linzess ...
Kidney Disease (2)
Hyperphosphatemia (1), Irritable Bowel Syndrome (1), Chronic Kidney Failure (1)
... accelerate the development of more precise screening tools and therapies for Barrett's esophagus and esophageal adenocarcinoma, the fastest growing form of cancer in the U.S ... Most cases of Barrett's stem from gastroesophageal reflux disease (GERD)-;chronic regurgitation of acid from the stomach into the lower esophagus ... that we know the cell of origin for Barrett's esophagus, the next step is to develop therapies that target these cells or the signaling pathways that ...
Oncology (6), Gastrointestinal Diseases (2), Stem Cell Research (1)
Barrett Esophagus (10), Esophageal Neoplasms (5), Adenocarcinoma (3)
NEJM - Physician's First Watch
Patients More Likely to Return Colon Cancer Screening Kits When Reminded by Live Phone Calls — Physician’s First Watch. By Amy Orciari Herman. Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM. For patients who are overdue in completing a home fecal immunochemical testing (FIT) kit, live phone call reminders may be more effective than text messages or ...
Oncology (2)
Colonic Neoplasms (2)
Clinical trial tests frankincense as potential breast, colon cancer treatment... clinical trial using frankincense to try to treat breast and colon cancer at the Medical University of South Carolina... takes advantage of the window of time between the initial diagnosis of breast or colon cancer and surgery to remove the cancer ...
Oncology (11)
Neoplasms (9), Colonic Neoplasms (4), Breast Neoplasms (3)
Stromal TARgeting for PAncreatic Cancer (STAR_PAC) - Full Text View. Pancreatic cancer (PDAC) is the fourth highest cancer killer worldwide and is responsible for 6% of cancer ... A main factor in the lack of treatment options for patients is that pancreatic cancer is surrounded by a thick scar tissue called the ...
Oncology (13)
Neoplasms (7), Pancreatic Neoplasms (6)
Clinical Pharmacology of FYU-981 (Subjects With Hepatic Insufficiency) - Full Text View. Primary Outcome Measures. Pharmacokinetics (Cmax: Maximum plasma concentration) [ Time Frame: 48 hours. Pharmacokinetics (Tmax: Time to reach the peak plasma concentration) [ Time Frame: 48 hours. Pharmacokinetics (T1/2: Elimination half-life of plasma concentration) [ Time Frame: 48 hours.
Hepatic Insufficiency (2)
Irritable bowel syndrome-subjective severity scores (IBS-SSS) ratings [ Time Frame: 4 weeks ... Visual analog scale for irritable bowel syndrome (VAS-IBS) ratings [ Time Frame: 4 weeks... Patients will be recruited from the clinic of Gastroenterology or Internal medicine as well as primary health care ... out protocols concerning Rom IV criteria (to validate that IBS criteria are filled) as well as IBS symptom rating scales ...
Irritable Bowel Syndrome (2)
Plasma Free Amino Acids in Patients With Hepatic Encephalopathy - Full Text View... in amino acid profiles observed in patients with liver cirrhosis are very specific and markedly differ from those observed ... current recommendation only includes oral BCAA to patients with liver disease who are intolerant to standard protein intake... on compound end points, which combine survival, hospitalization, and cirrhosis complications.
Neuroscience (1), Infectious Diseases (1)
Hepatic Encephalopathy (8), Cirrhosis (1), Liver Diseases (1)
Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma - Full Text View This is a randomized noninferiority multicenter trial. Patients will be stratified according to the participating hospital. Patients will be randomized to one of the treatment arms. Arm A: Patients will receive surgical resection, including Ivor Lewis esophagectomy or McKeown esophagectomy and systematic lymphadenectomy.
Squamous Cell Carcinoma (2)
Hepatocellular Carcinoma in Patients With a Cirrhosis Due to an Alcoholic or a Non Alcoholic Fatty Liver Disease - Full Text View ... Global prevalence of Non Alcoholic Fatty Liver Diseases (NAFLD) ranges from 22% to 28%.The spectrum of these hepatic abnormalities extends from isolated steatosis to steatohepatitis (Non Alcoholic Steato-Hepatitis, NASH) and steatofibrosis leading to cirrhosis and hepatocellular carcinoma ...
Infectious Diseases (4)
Cirrhosis (6), Hepatocellular Carcinoma (6), Alcoholic Fatty Liver (4)
Yttrium-90 Radioembolization + Nivolumab for Liver + Extra-hepatic Metastases From Colorectal Cancer - Full Text View... The main goal of the Phase Ib portion of this research study is to see at ... blocks certain blood vessels, and radiation therapy, which kills cancer cells) to treat cancer tumors in the liver... are placed inside the blood vessels that feed the tumor in the liver.
Oncology (7)
Neoplasms (10), Colorectal Neoplasms (2)
Radiopaque Hydrogel in Patients Undergoing Radiotherapy for Pancreatic Cancer - Full Text View... challenge to dose-escalation with IMRT (intensity modulation radiation therapy) or SBRT is the sensitivity of the surrounding gastrointestinal organs, particularly the small bowel which is directly adjacent to ... Patients with a pathologically confirmed diagnosis of BR/LAPC pancreatic adenocarcinomas indicated for neo-adjuvant image-guided radiotherapy with ...
Oncology (6)
Pancreatic Neoplasms (5), Adenocarcinoma (2), Neoplasms (1)
Comparison of Early Vs Delayed Feeding on Rebleeding Following Endoscopic Ligation for Acute Esophageal Variceal Bleeding - Full Text View Primary Outcome Measures: Secondary Outcome Measures: There has not been much studies conducted to address this issue however most of the recommendations are made in view of preventing any complications following procedures.
Varicose Veins (3), Deglutition Disorders (1), Angiodysplasia (1)
United Press International - UPI (United States)
Liquid biopsy may provide easier, earlier liver cancer detection... may be a faster and better way to detect liver cancer... HCC is the most common form of primary liver cancer in adults and is one of the leading causes ... California has one of the highest rates of liver cancer in the U.S. This novel report has major ...
Oncology (14), Infectious Diseases (1)
Neoplasms (18), Liver Neoplasms (5), Steatohepatitis (1)
Prostate Cancer News
Blood test may find liver cancer earlier, improve survival - Prostate Cancer News Today. Blood test may find liver cancer earlier, improve survival... Liver cancer can be caught at an early stage through a ... activity, caused by a process called methylation, that indicate liver cancer, said Kang Zhang, M.D., the study’s senior author ...
Oncology (6)
Liver Neoplasms (5), Prostatic Neoplasms (1)
... pathway that allows the p53 protein to exert anti-tumor effects on pancreatic tumors—and a specific p53 mutation that strengthens this cancer-fighting capability ... In pancreatic cancer, researchers are focusing on attacking tumors from many different angles ... described how inhibiting the enzyme arginase 2 (ARG2) slowed pancreatic tumor growth in obese mice by preventing the cancer cells from metabolizing nitrogen ...
Oncology (16), Anti-Obesity and Weight Loss (1)
Neoplasms (21), Pancreatic Neoplasms (7), T-Cell Lymphomas (1)
Feasibility of Molecular Biology in Pancreatic Cyst Tumors - Full Text View... Comparison between gene mutations found into the pancreatic cystic tumor fluid to gene mutations found into tissue specimen [ Time ... the feasibility of the molecular biology analysis of the pancreatic cystic tumor fluid to distinguish the pancreatic cysts... fluid DNA molecular analysis in patients with suspected cystic tumours of pancreas in whom EUS FNA is clinically indicated.
Neoplasms (5), Pancreatic Cysts (3), Neoplastic Cell Transformation (1)
New studies provide insight into treatments for Barrett's esophagus... The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE ... believed to be most commonly due to inflammation from gastroesophageal reflux disease (GERD... shown to be a safe, well-tolerated, and effective therapy for cellular changes occurring with Barrett's esophagus (BE.
Gastrointestinal Diseases (2)
Barrett Esophagus (7), Metaplasia (6), Neoplasms (6)
CBS News
California's hepatitis A outbreak may linger for years, experts say... hepatitis A outbreak in California... The contagious, liver-damaging illness has infected at least 568 people since November, mainly in San ... say the most effective way to fight the contagious liver disease is by vaccinating at-risk populations, which include first ...
Infectious Diseases (5), Vaccines (2)
Hepatitis A (5), Infections (1), Jaundice (1)
Study findings provide new insight into inflammatory bowel disease... Netherlands, provide the first evidence that patients with debilitating inflammatory bowel disease lack sufficient quantities of a protein that comes from ... There is currently no cure for inflammatory bowel disease (IBD... Crohn's and ulcerative colitis are debilitating diseases that belong to a group of conditions known as inflammatory bowel diseases ...
Immune System Diseases (10), Oncology (1), Pediatrics (1)
Inflammatory Bowel Diseases (6), Ulcerative Colitis (2), Diarrhea (1)
Efficacy of Low-FODMAPs Dietary Therapy for Irritable Bowel Syndrome in China - Full Text View... 3 weeks later) about quality of life evaluated by IBS-QOL... meet the inclusion criteria will be asked to complete IBS Baseline Assessment Questionnaires according to Rome III and Rome ... IBS Symptoms Severity Scores (IBS-SSS) is evaluated every week and the dietitian who ...
Irritable Bowel Syndrome (2)
... the Effectiveness and Clinical Practice Use of Glecaprevir Plus Pibrentasvir in Patients With Chronic Hepatitis C Genotypes 1 to 6 - Full Text View... plus pibrentasvir (GLE/PIB) for the treatment of genotypes 1 to 6 of chronic hepatitis C (CHC) viral infection has been shown to be safe and effective in randomized ...
Infectious Diseases (3)
Chronic Hepatitis C (3), Infections (1)
Kaiser Health News
How San Diego’s Hepatitis A Outbreak May Have Had Its Roots In A ... Stat: Hepatitis A In San Diego: An Outbreak Waiting To Happen. he hepatitis A outbreak now roiling this well-heeled, coastal city ... Hepatitis A is transmitted through contact with feces from an ... Los Angeles Times: California's Deadly Hepatitis A Outbreak Could Last Years, Official Says.
Infectious Diseases (9), Vaccines (1)
Hepatitis A (7), Hepatitis (2)
... based study to examine the relationship of oral and pancreatic microbiome, and their functions, to pancreatic cancer risk... of specific oral bacteria and their functional relationship to pancreatic cancer will advance scientific knowledge on the etiology of pancreatic cancer ... oral pathogens have been associated with increased risk of pancreatic cancer; however, direct relationships of oral microbes with pancreatic cancer have not been evaluated in prospective studies ...
Oncology (17), Infectious Diseases (1)
Pancreatic Neoplasms (11), Neoplasms (4), Skin Neoplasms (1)
The Association Between the Microbiological Environment in Colon and Colorectal Disease - Full Text View... Cancer, inflammatory bowel disease and diverticulosis result in substantial patients suffering and health ... a major role in the causal chain for many diseases, and the research on the microbial environment in the colon in relation to bowel disease is increasingly intense although the possibility for analysis of ...
Oncology (1)
Neoplasms (1), Inflammatory Bowel Diseases (1), Diverticulosis (1)
Mitochondrial Metabolism and Hepatic Complications of Obesity - Full Text View... Association between nonalcoholic steato-hepatitis and mitochondria morphological markers [ Time Frame: Until 6 month. The study aims to characterize mitochondrial metabolism in the liver of obesity surgery patients and to study its relationships with hepatic steatosis, inflammation, and fibrosis ... The protocols involves a per-operative hepatic needle biopsy for mitochondria characterization and histological scoring of ...
Anti-Obesity and Weight Loss (3), Infectious Diseases (1)
Obesity (3), Fibrosis (2), Hepatitis (1)
Although fatty liver disease usually does not progress to dangerous levels of liver inflammation, the condition is an increasing concern as its rates climb in ... As obesity spreads worldwide, so will the burden of fatty liver disease and associated liver failure, which is predicted to become the most common factor ...
Anti-Obesity and Weight Loss (11), Endocrine Disorders (5)
Fatty Liver (11), Obesity (5), Diabetes Mellitus (3)
NEJM - Physician's First Watch
Gun Control Editorial / Noontime Light for Bipolar Depression / Kentucky Gastroenterology Opportunity — Physician’s First Watch. By the Editors. Take a look at today's offering from NEJM Group. New England Journal of Medicine: The Journal's editors ask: "For years under both Republican and Democratic administrations, Congress has been afraid to do anything about regulating guns, even those that are designed for mass ...
Bipolar Depression (3)
Personalized Research on Diet in Ulcerative Colitis and Crohn's Disease - Full Text View. Experimental: Specific Carbohydrate Diet (First. Participants will be following the Specific Carbohydrate Diet (SCD. Allowed foods include meat/fish/poultry, eggs, some legumes (e.g., lentils and split peas are permitted, chickpeas and soybeans are not), fully fermented yogurt, non-starchy vegetables, ripe fruit, nuts/seeds, honey ...
Immune System Diseases (2)
Ulcerative Colitis (2)
Phase I/Ib Study of LHC165 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies - Full Text View... This is a Phase I/Ib, multi-center, open-label study to characterize the safety, tolerability, PK, PD, and preliminary antitumor activity of LHC165 single agent and in combination ...
Neoplasms (3)
Version: V1.1 8/15/2017 A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer - Full Text View. Inclusion Criteria. Previously untreated, apparently resectable, adenocarcinoma of the pancreas at registration. Age greater than or equal to 18 years.
Oncology (4)
Pancreatic Neoplasms (4), Adenocarcinoma (1), Hypercalcemia (1)
Study of the Interest of Pursuing or Not the Chemotherapy for Patients With Metastatic Esophageal Cancer - Full Text View Primary Outcome Measures: Secondary Outcome Measures: Estimate efficiency in term of overall survival, of pursuing chemotherapy [ Time Frame: From date of randomization until the date of death from any cause, up to 8 months after the beginning of the treatment ] beyond 6 weeks of treatment compared to a group that interrupted the treatment at 6 weeks Estimate the
Oncology (2)
Esophageal Neoplasms (2), Neoplasms (1)
A Phase II, Open Label Study to Evaluate the Safety and Efficacy of BLEX 404 Oral Liquid Combined With Gemcitabine Monotherapy in Patients With Advanced Inoperable or Metastatic Pancreatic Cancer - Full Text View. Experimental: BLEX 404 Oral Liquid. During Phase I study (dose escalation), a standard 3+3 design will be followed, and the dose range is 3 to 10 ...
Oncology (2)
Pancreatic Neoplasms (2)
World Pharma News
... is estimated there will be approximately 41,000 new diagnoses of liver and intrahepatic bile duct cancers in the U.S. and an estimated 29,000 people will die from the disease.(2) HCC is the most common type of primary liver cancer, cancer that starts in the liver.(6) In addition to HBV and HCV infections, gender, race and ethnicity, cirrhosis, obesity, type 2 diabetes ...
Oncology (68), Infectious Diseases (3), Endocrine Disorders (1)
Liver Neoplasms (46), Neoplasms (22), Hepatocellular Carcinoma (5)
BBC News (United Kingdom)
Lauren is researching the impact bowel conditions like Irritable Bowel Syndrome can have... Lauren White is researching the impact conditions like IBS can have on people's lives by mapping the toilets ... When you've got conditions like IBS, toilets can be the thing you think about every ... She says: "We need to start those conversations around IBS - it's a very real condition that affects people.
Irritable Bowel Syndrome (2)
NEJM - Physician's First Watch
Acute Liver Failure Case / Autism Recurrence in Siblings / California Family Medicine Opportunities — Physician’s First Watch... NEJM Clinical Practice Center: Case Record: A 65-year-old woman with autoimmune hepatitis presented for an evaluation for liver transplantation. Fever, hypotension, and worsening liver and renal failure developed. A blood culture revealed corkscrew-shaped gram-negative rods.
Neuroscience (3), Immune System Diseases (1), Infectious Diseases (1)
Autistic Disorder (3), Acute Liver Failure (2), Kidney Failure (1)
Healthline News
Personalized Diets May Help People with Irritable Bowel Syndrome... not be anything new as a way to treat irritable bowel syndrome (IBS... Dr. Michelle S. Cohen, an assistant professor of gastroenterology at the Icahn School of Medicine at Mount Sinai, explained that IBS is divided into different categories based on bowel habits ... IBS is a gastrointestinal ailment, but it’s a separate condition from irritable bowel disease (IBD ...
Pediatrics (1), Infectious Diseases (1)
Irritable Bowel Syndrome (3), Diarrhea (1)
Diaphragmatic Myofascial Release in Gastroesophageal Reflux Disease - Full Text View... to study the effects of diaphragmatic myofascial release in patients with gastroesophageal reflux disease (GERD... diaphragm muscle surrounds the lower esophageal sphincter, and helps to prevent gastroesophageal reflux... Specific quality of life for gastrointestinal disease: Gastrointestinal Quality of life Index (GIQLI.
Gastrointestinal Diseases (10)
Gastroesophageal Reflux (11), Gastrointestinal Diseases (1)
Use of Mesenchymal Stem Cells in Inflammatory Bowel Disease - Full Text View. Experimental: Wharton Jelly Mesenchymal stem cells. Wharton Jelly Mesenchymal stem cells will be given as a cell suspension in aseptic buffered solution in disposable vials with no preservative agents. The cells will be injected every two weeks at a total of three doses, 120 million cells in 10mls ...
Inflammatory Bowel Diseases (2)
Biologic Basis of Liver Cancer From Chronic Hepatitis B - Full Text View. Liver Biopsy slides. Up to twenty (20) de-identified hepatocellular carcinoma (HCC) tissue sections on biopsy slides or frozen sections and associated information such as age, sex, race, ethnicity, treatment status, pathological diagnoses, and date of procedure will be obtained from UC Davis Cancer Center Biorepository (CCB) and ...
Oncology (3), Infectious Diseases (2)
Liver Neoplasms (2), Chronic Hepatitis B (2), Neoplasms (1)
Non Alcoholic Fatty Liver Disease: Nutritional Epidemiology and Lifestyle Medicine - Full Text View. The study is an open-label intervention non pharmacological Cohort Study without control arm in patients with Non Alcoholic Fatty Liver Disease (NAFLD) and in healthy subjects. The intervention in patients with NAFLD is educational, providing personalized suggestions to improve diet and physical activity; the intervention in ...
Alcoholic Fatty Liver (3)
Contrast-Enhanced Ultrasound in Diagnosing Patients With Liver Cancer Undergoing Yttrium-90 Radioembolization - Full Text View. Primary Outcome Measures. PRIMARY OBJECTIVES. I. Investigate the relationship between hepatocellular carcinoma (HCC) tumor perfusion on pre-procedural contrast-enhanced ultrasound (CEUS) time intensity curve (TIC) and post-procedural Yttrium-90 (90Y) microsphere distribution after 90Y radioembolization (RE.
Oncology (2)
Liver Neoplasms (2), Neoplasms (2), Hepatocellular Carcinoma (1)
With hepatitis C virus starting to look like a conquered foe, attention is turning to the fight against chronic hepatitis B virus (HBV), and Vivek Ramaswamy’s Roivant has just ... off the infection, but a sizable minority develop chronic disease that resists drug treatment and increases the risk of liver damage, cirrhosis and liver cancer ...
Infectious Diseases (6), Immune System Diseases (1), Oncology (1)
Hepatitis B (3), Alzheimer Disease (1), Cirrhosis (1)
Observational Study of Definitive (Chemo)Radiotherapy on Patients With Esophageal Cancer - Full Text View This study is currently recruiting participants. See Verified September 2017 by Zefen Xiao, Chinese Academy of Medical Sciences Sponsor: Identifier: NCT03298204 First Posted: October 2, 2017 Last Update Posted: October 2, 2017 The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
Oncology (6)
Neoplasms (6), Esophageal Neoplasms (2)
Seres plots ulcerative colitis trial drive after posting 1b data... from a phase 1b of SER-287 in ulcerative colitis... 287 in mild, moderate and severe forms of ulcerative colitis, in maintenance after induction therapy, and we also intend ... assess development in Crohn’s disease, and pediatric forms of inflammatory bowel disease.
Infectious Diseases (1)
Ulcerative Colitis (6), Inflammatory Bowel Diseases (1)
62. Zinc may help stop growth of esophageal cancer  
Date: 10/02/2017 08:48
Previous studies have indeed shown that zinc can protect the esophagus from cancer, but the mechanism through which this was achieved was not clear. Esophageal cancer is the sixth leading cause of human cancer deaths around the world, with an estimated 16,000 people dying from esophageal cancer in the United States in 2016.
Oncology (16)
Esophageal Neoplasms (9), Neoplasms (7)
... Anti-TNF Alpha and/or Anti-integrin Refractory Ulcerative Colitis - Full Text View... Change of Inflammatory Bowel Disease Questionnaire from baseline [ Time Frame: at 12- and 26 ... The proportion of patients with Inflammatory Bowel Disease Questionnaire (IBDQ) response [ Time Frame: at 12- and 26 ... Neihulizumab in patients with moderate to severe active ulcerative colitis and who has failed or are intolerant to anti ...
Ulcerative Colitis (3), Inflammatory Bowel Diseases (2)
64. Primary Liver Cancer Cohort of South China  
Date: 09/29/2017 07:23
Primary Liver Cancer Cohort of South China - Full Text View... Primary liver cancer (PLC) is highly malignant with high mortality which is particularly popular ... Many factors are believed to associate with the occurrence and prognosis of liver cancer... influencing the occurrence and long-term survival of patients with primary liver cancer.
Oncology (5)
Liver Neoplasms (5)
Paracetamol Metabolism Research in Postoperative Hepatic Surgery - Full Text View... day kinetics of plasma paracetamol levels in postoperative major hepatic surgery (resection greater than or equal to three hepatic segments) compared with less extensive liver resection and hepatic re-intervention ... The clearance of indocyanine green is a marker of hepatic perfusion but also of the proper hepatocyte functioning, if ...
NEJM - Physician's First Watch
Hepatitis C Testing Rates and Care Quickly Increase After Adoption of State Law — Physician’s First Watch... A New York State law requiring healthcare providers to offer hepatitis C virus (HCV) antibody testing to patients born between 1945 and 1965 led to rapid increases in HCV testing and linkage to HCV ...
Infectious Diseases (3)
Hepatitis C (3), Infections (1)
ABC News
San Diego increases homeless citations in hepatitis outbreak... homeless people regularly camp during ongoing efforts to sanitize neighborhoods to control the spread of hepatitis A... San Diego County is battling an epidemic of hepatitis A, a contagious liver disease that has killed 17 people and hospitalized at least 300 more ...
Infectious Diseases (4)
Hepatitis A (2), Hepatitis (2), Liver Diseases (1)
On the Cyberknife Dose Fraction of Liver Cancer Treatment - Full Text View. Experimental Group One. In this group ,the participants receive the dose fraction of 49Gy/7f (BED 83.3Gy) by cyberknife. Radiation: Dose fraction forms. The investigators divide the participants randomly into 3 groups by SPSS 19.0.Three groups participants receive the different dose fraction(49Gy/7f,54Gy/6f and ...
Oncology (2)
Liver Neoplasms (2)
Selective Pelvic Lymphadenectomy for IB-IIA Cervical Cancer - Full Text View... 3.Protocol Patients with stage IB-IIa cervical cancer were randomly divided into two groups(Control group and Experimental group).Frozen pathological examination will be performed during the operation, and patients with positive lymph node metastasis will undergo radical ...
Oncology (7)
Lymphedema (8), Uterine Cervical Neoplasms (4), Neoplasms (2)
Circulating Tumor Cells in mCRC for Liver Resection - Full Text View... This is a single-center prospective study to evaluate the predictive value of circulating tumor cells (CTC) in patients with metastatic colorectal cancer who are planned to have curative resection of liver metastasis. Blood will be taken from patients within 7 days before liver resection.
Oncology (2)
Circulating Neoplastic Cells (4), Colorectal Neoplasms (1)
Stratification of Chronic Alcoholic Liver Diseases (SCALE Study) - Full Text View. Primary Outcome Measures:. 4-week mortality [ Time Frame: 4 weeks ]. mortality rate. 12-week mortality [ Time Frame: 12 weeks ]. mortality rate. Secondary Outcome Measures:. Intervention Details:. Other: standard therapy. standard therapy,non-interventional study.
Alcoholic Liver Diseases (2)
Prostate Cancer News
September 28, 2017 Experts from United European Gastroenterology (UEG), presenting at the European Digestive Cancer Days (EDCD) Conference in Prague today, are calling on ... European governments to focus their efforts on developing early diagnosis techniques, in order to save thousands of lives from digestive cancers including a more targeted approach to ensure at risk ...
Oncology (2)
Neoplasms (1), Prostatic Neoplasms (1)
Experts from United European Gastroenterology (UEG), presenting at the European Digestive Cancer Days (EDCD) Conference in Prague today, are calling on ... European governments to focus their efforts on developing early diagnosis techniques, in order to save thousands of lives from digestive cancers including a more targeted approach to ensure at risk ...
Oncology (29)
Neoplasms (14), Colorectal Neoplasms (3), Stomach Neoplasms (3)
Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006) - Full Text View. Primary Outcome Measures. Area under the concentration-time curve of MK-3866 from time 0 to infinity (AUC0-∞) [ Time Frame: Predose, 0.5 (end of infusion), 0.75, 1, 1.5, 2, 3, 4.5, 6, 8, 10, 12, 24, 48 (all Panels), and 72 (Panels A ...
Study of Recombinant Human Serum Albumin/Interferon alpha2b Fusion Protein in Hepatitis B Patient - Full Text View. Experimental: Human Serum Albumin/interferon alpha2b. Human Serum Albumin/interferon alpha2b fusion protein 600-900μg,once per two weeks. Biological: Human Serum Albumin/interferon alpha2b fusion protein. In experiemental groups, each subject will recieve 600,750,900mg once per two weeks during multiple ...
Infectious Diseases (2)
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The HepQuant SHUNT Test for Monitoring Liver Disease and Treatment Effects by Measuring Liver Function and Physiology - Full Text View ... clinical trials,GS-US-416-2124 trial of Alcoholic Hepatitis, GS-US-384-1943 trial of non-alcoholic steatohepatitis ... GS-US-384-1944 trial of NASH and compensated cirrhosis (STELLAR-4.
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Oxaliplatin in PIPAC for Nonresectable Peritoneal Metastases of Digestive Cancers - Full Text View. Current curative treatment of digestive peritoneal carcinomatosis consists of complete cytoreduction surgery associated with intraperitoneal chemotherapy ... investigator propose a phase 1 study, in colorectal and stomach cancer, with oxaliplatin doses escalation in Pressurized Intraperitoneal aerosol chemotherapy ... few risks and thus improve survival in patients with digestive peritoneal carcinoses, increasing access to cytoreductive surgery.
Oncology (1)
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A Self-efficAcy Intervention to reDuce Injecting Risk behAviour and hePatitis c reinfecTion Rates - Full Text View... Self-reported therapeutic alliance with provider of hepatitis C treatment care over treatment duration... Self-reported perception of hepatitis C as an illness. Eight items scored 1-10 (1 no impact on quality of life, 10 high impact on quality of life.
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Kaiser Health News
Nation’s Organ Donation Network Wants To Make Liver Transplants ‘A Little Bit More Equal’... Himanshu Patel ran a convenience store in Georgia until about a year ago, when his liver failure got so bad he had to quit. I just couldn't stand up on my feet at all," says Patel, 39, of Waycross, Ga. "I just had to stop working ...
Neuroscience (3)
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80. Mexican Americans at higher risk for liver cancer  
Date: 09/25/2017 20:54
United Press International - UPI (United States)
Chronic liver disease, which can lead to liver cancer, is a leading cause of mortality in Mexico and ... Having a combination of risk factors for liver disease, such as obesity and excessive drinking, or diabetes and chronic hepatitis C infection, has been shown to increase risk of liver cancer," she said ...
Oncology (14), Endocrine Disorders (2), Infectious Diseases (2)
Liver Neoplasms (9), Neoplasms (5), Liver Diseases (3)
Prostate Cancer News
Announces Clinical Collaboration to Evaluate IO-Based Combination Therapies in Pancreatic Cancer - Prostate Cancer News Today. 16:04 GMT. 4-traders. Phase 2, randomized, double-blind, placebo-controlled trial of indoximod in combination with durvalumab, an immune checkpoint inhibitor, along with gemcitabine/ABRAXANE® (nab-paclitaxel) and durvalumab with gemcitabine/ABRAXANE® versus gemcitabine/ABRAXANE® NewLink Genetics Corporation (Nasdaq: NLNK) today announced ...
Oncology (3)
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... a promising positive factor for the continued development of treatments for colon cancer," confirms Yvonne Wettergren, Associate professor in Molecular Medicine at ... intestinal microflora composition, studied in biopsies, was different in tumor tissue and the surrounding mucosa in patients with colon cancer compared with healthy individuals ... acidophilus NCFM, previously proved to reduce the growth of colon tumors in mice, and also reduced the amount of carcinogenic ...
Oncology (10)
Neoplasms (6), Colonic Neoplasms (6), Intestinal Polyps (1)
Trial of Infusional FOLFIRINOX in First Line Treatment of Advanced Biliary Tract Cancers - Full Text View Experimental: Experimental single arm Chemotherapy using the FOLFIRINOX regimen will be given every 2 weeks for a total of 12 cycles. FOLFIRINOX consist of: Oxaliplatin-85 mg/m2 IV Day 1 Leucovorin-400 mg/m2 IV Day 1 Irinotecan-180 mg/m2 IV Day 1 Fluorouracil (FU)-400 mg/m2 IV bolus Day 1 Fluorouracil 2400 mg/m2 infused over 46 hours starting day 1 Combination Product: FOLFIRINOX combination chemotherapy using Oxaliplatin,
FOcus on Reducing Dose-limiting Toxicities in Colon Cancer With Resistance Exercise Study - Full Text View... training (RT) intervention study for Stage II and III colon cancer patients undergoing chemotherapy. Participants will be 180 newly diagnosed Stage II and III colon cancer patients from Kaiser Permanente of Northern California (KPNC), the ...
Oncology (7)
Colonic Neoplasms (5), Neoplasms (2)
Merck's Keytruda resumes regulatory hot streak with stomach cancer approval... nods, Merck's high-flying Keytruda nets priority status in stomach cancer... Meanwhile, though, Merck sees more potential in the stomach cancer arena, where Keytruda recently posted additional positive data... the FDA had approved Opdivo as a second-line treatment for the most common form of liver cancer.
Oncology (13)
Stomach Neoplasms (7), Neoplasms (2), Microsatellite Instability (1)
Gilead nabs Chinese nod for Sovaldi, eyeing world's largest hepatitis C patient base... cut deals for generic makers to sell its pricey hepatitis C cures in emerging markets at super deep discounts ... For China, hepatitis B already has long been seen as a big ... to quickly address the emerging public health concerns over hepatitis C. While public education is still playing catchup, the ...
Infectious Diseases (5), Immune System Diseases (1)
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Prostate Cancer News
NewLink Genetics Announces Clinical Collaboration to Evaluate IO-Based Combination Therapies in Pancreatic Cancer - Prostate Cancer News Today. 10:12 GMT. AMES, Iowa, Sep 25, 2017 (GLOBE NEWSWIRE via COMTEX) -- NewLink Genetics Corporation NLNK, +1.67% today announced that it has entered into a clinical collaboration agreement with AstraZeneca to evaluate the combination of indoximod, NewLink Genetics' small molecule ...
Oncology (3)
Pancreatic Neoplasms (2), Prostatic Neoplasms (1)
Study finds new treatment technique for displaced gastric mucosa in the esophagus... consolidate the success of the new treatment technique, lead investigator Sebastian Schoppmann, surgeon and Head of the Diseases of the Stomach and Oesophagus working group at MedUni Vienna's Department of Surgery, is currently preparing a randomized, controlled trial ...
Oncology (1)
Gastroesophageal Reflux (1), Esophageal Neoplasms (1)
Sexual Hepatitis C in HIV Positive Men Who Have Sex With ... Describing the natural history of sexual hepatitis C in HIV positive MSM [ Time Frame: At inclusion ... Hepatitis C (HCV) is considered in part as a sexually ... However, people are increasingly infected with the hepatitis C virus, especially HIV-positive MSM.
Infectious Diseases (8), Immune System Diseases (1)
Hepatitis C (8), Infections (1)
... Maintenance Treatment in Participants With Moderate to Severe Ulcerative Colitis Who Achieved Clinical Response in Induction Studies - Full Text ... Change from Induction Study Baseline in Inflammatory Bowel Disease Questionnaire (IBDQ) domains and Total Absolute Scores in Inflammatory Bowel Disease Questionnaire [ Time Frame: Week 12 up Week 52 ... for measuring the disease-specific HRQL in participants with inflammatory bowel disease, including UC.
Blood Disorders and Hematology (1)
Diarrhea (4), Inflammatory Bowel Diseases (3), Ulcerative Colitis (2)
Kaiser Health News
VA Steps Up Efforts To Screen And Treat Veterans For Hepatitis C... KQED: In The Battle Against Hepatitis C, The VA Takes The Lead... Hepatitis C experts and advocates have praised the VA for its proactive approach, and say it should be a model for other government health programs, and ...
Infectious Diseases (4), Cardiovascular Diseases (1), Endocrine Disorders (1)
Hepatitis C (4), Heart Diseases (1), Allergy (1)
Healthline News
Wooten said 25 percent of those diagnosed with hepatitis A in this outbreak also had hepatitis B or C as well ... Hepatitis A is a viral infection that leads to inflammation of the liver ... A person infected with hepatitis A usually doesn’t develop a chronic infection unlike other forms of viral hepatitis ... However, the liver infection can last for months or even cause death in ...
Infectious Diseases (14), Cardiovascular Diseases (1), Vaccines (1)
Hepatitis A (8), Infections (6), Hepatitis (5)
93. MR Assessment of Hepatic Hydatid Disease  
Date: 09/21/2017 12:00
MR Assessment of Hepatic Hydatid Disease - Full Text View... Approximately 75% of CE involves the liver, with treatments incurring significant cost and patient morbidity... for each stage of the natural life-cycle of hepatic CE will enable improved diagnosis and therapeutic triage... quantitative MRI methods in the assessment of active/inactive hepatic CE.
Infections (3), Cysts (1)
... Enasidenib (CC-90007) in Subjects With Moderate and Severe Hepatic Impairment... enasidenib (CC-90007) in subjects with moderate and severe hepatic impairment, and in matched healthy control subjects with normal hepatic function ... Degrees of hepatic impairment will be determined during screening by the subject's ... to Pugh's Modification of Child's Classification of Severity of Liver Disease.
Liver Diseases (1)
NEJM - Physician's First Watch
Inflammatory Bowel Disease in Childhood Tied to Higher Cancer Risk Later — Physician’s First Watch... Children diagnosed with inflammatory bowel disease (IBD) face increased cancer risk in both childhood and adulthood, according to a study ... In particular, risk increases were highest for liver, colorectal, small bowel, nonmelanoma skin, and lymphoid cancers.
Oncology (6)
Neoplasms (6), Inflammatory Bowel Diseases (3)
96. Southern California battles hepatitis A outbreak  
Date: 09/20/2017 19:21
CBS News
Southern California battles hepatitis A outbreak - Videos... Lines are long and constant at pop-up clinics around San Diego, where hundreds of people have waited to get free hepatitis A vaccines. There's a desperate race against time to stop the hepatitis A virus from spreading. Mireya Villarreal reports.
Infectious Diseases (4), Vaccines (1)
Hepatitis A (4)
97. Southern California battles hepatitis A outbreak  
Date: 09/20/2017 19:09
CBS News
Race against time to stop hepatitis A virus from spreading in San Diego... outbreak of hepatitis A... area, where hundreds of people waited to get free hepatitis A vaccines... There's a desperate race against time to stop the hepatitis A virus from spreading, especially among the area's homeless ... There's a desperate race against time to stop the hepatitis A virus from spreading in San Diego.
Infectious Diseases (8), Vaccines (2)
Hepatitis A (7), Hepatitis (1)
Kaiser Health News
State Highlights: States, Localities Face High Costs For Retiree Health Benefits; Hepatitis A Outbreak Declared In Los Angeles... Los Angeles Times: Health Officials Declare Hepatitis A Outbreak In L.A. County. Los Angeles County health officials declared a hepatitis A outbreak Tuesday, days after a public health emergency was announced ...
Infectious Diseases (6), Oncology (3)
Hepatitis A (4), Neoplasms (3), Sore Throat (2)
Crohn's & Colitis Foundation and Oxford University Press partner to publish Inflammatory Bowels Diseases journal ... Inflammatory Bowel Diseases is the first journal dedicated exclusively to inflammatory bowel diseases (IBD ... The editors of Inflammatory Bowel Diseases, Dr. Bret Lashner and Dr. Fabio Cominelli, commented on the shared mission of Inflammatory Bowel Diseases and the press, noting that they will "work with ...
Inflammatory Bowel Diseases (7), Colitis (5)
CBS News
Hepatitis A outbreak hits Los Angeles after 2 cases confirmed. LOS ANGELES -- Los Angeles County has a hepatitis A outbreak based on two "community-acquired" cases that ... We are in the situation of a hepatitis A outbreak as of this morning," Public Health Department ... because of the liver disease outbreak that has killed 16 people and hospitalized 300 ...
Infectious Diseases (9), Vaccines (1)
Hepatitis A (9), Communicable Diseases (1), Jaundice (1)
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