AbstractText: To investigate predictors of 10-year risk of revision and 1-year risk of prostheticjointinfection (PJI) and death following total hip/total knee arthroplasty (THA/TKA) in (1) patients with rheumatoid arthritis (RA) compared with patients with osteoarthritis (OA); and (2) patients with RA treated with biological ...
Immune System Diseases (3), Muscular and Skeletal Diseases (2) Rheumatoid Arthritis (3), Infections (3), Osteoarthritis (1), more mentions
Abstract: Older adults are at increased risk for septicarthritis and prostheticjointinfections (PJI), owing at least in part to comorbid conditions and ... the epidemiology, pathogenesis, clinical manifestations, diagnosis, management, and prevention of septicarthritis and PJI in older adults Keyword: Biofilm... Keyword: Prostheticjointinfection. Keyword: Septicarthritis.
Muscular and Skeletal Diseases (4) Infections (5), Bacterial Arthritis (4), Staphylococcal Infections (1), more mentions
... metalloproteinase-1 (MMP-1) gene polymorphisms on the onset of osteomyelitis in Chinese Han population.In all, 80 osteomyelitis patients (case group) and 81 healthy people (control group) were ... Whereas, the -519G allele may be a susceptible factor for osteomyelitis (OR 1.622, 95% CI 1.038-2.536).The MMP-1 -1607 ...
Patients were diagnosed with a previously unsuspected prostheticjointinfection (PJI) if two or more cultures were positive with the ... The primary outcome measure was infection-free implant survival at two years AbstractText: The incidence of unsuspected PJI ... Following revision TKA, the rate of infection-free implant survival in patients with an unsuspected PJI was 88% (95 ... Keyword: Prostheticjointinfection.
AbstractText: Tubercular prostheticjointinfection (TB-PJI) is an uncommon complication. Lack of evidence of systemic tuberculosis and clinical suspicion could bring a delay in the time of the diagnosis. The aims of this study are to underline the importance of awareness and suspicion of mycobacterial infection in the differential diagnosis in PJI and to evaluate the appropriateness of different ...
Cardiovascular Diseases (2) Infections (3), Tuberculosis (2), more mentions
PURPOSE: This study aimed at describing the use of oral cyclines (i.e., doxycycline and minocycline) as suppressive antibiotic therapy (SAT) in patients with periprosthetic joint infections (PJIs).
METHODS: Medical charts of all patients with surgical revisions for PJIs who were given cycline-based SAT because of a high failure of various origins were reviewed. Data regarding tolerability and effectiveness of cycline-based SAT were analysed.
RESULTS: Seventy-eight patients of mean age 64 ± 17 years received cycline-base SAT in the period from January 2006 to January 2014. PJIs involved the knee in 37 patients (47%), the hip in 35 (45%), the elbow in 4 (5%), and the shoulder in 2 (3%) and were qualified as early in 31 patients (39.7%). Staphylococcus spp. were the most common pathogens accounting for 72.1% of the total number of bacterial strains identified. All included patients had surgery which consisted in debridement and implant retention in 59 of them (75.6%). Doxycycline and minocycline were prescribed as SAT in 72 (92%) and 6 (8%) patients, respectively. Adverse events were reported in 14 patients (18%), leading to SAT discontinuation in 6 of them (8%). After a mean follow-up of 1020 ± 597 days, a total of 22 (28.2%) patients had failed including 3 cases (3.8%) with documented acquisition of tetracycline resistance in initial pathogen(s).
CONCLUSIONS: Our results suggest that oral cyclines used as SAT in patients treated for PJI have an acceptable tolerability and effectiveness and appear to be a reasonable option in this setting.
Abstract: We report two unrelated cases of tenosynovitis caused by Mycobacterium malmoense in kidney transplant recipients... Both cases illustrate the doctor's delay in diagnosing mycobacterial infections, and remind us that nontuberculous mycobacterial infections should be part of the differential diagnosis of tenosynovitis, especially in immunocompromised patients... Keyword: tenosynovitis.
Infectious Diseases (1) Tenosynovitis (4), Infections (3), more mentions
... ligament (ACL) graft removal versus retention in the setting of septicarthritis following reconstruction using an expected value decision analysis AbstractText: A ... years and those previously treated for either ACL injury or septicarthritis, or both, were excluded from the analysis to minimize bias ... by patients over graft retention in the setting of postoperative septicarthritis when consideration was given to the probabilities of wellness, nonoperative ...
Muscular and Skeletal Diseases (4) Bacterial Arthritis (4), more mentions
AbstractText: To investigate arthroscopic management of native shoulder joint septicarthritis-specifically, indications, patient outcomes, and complications AbstractText: PubMed, MEDLINE, and ... revision arthroscopic procedures, 7 (6%) who underwent open arthrotomy for septicarthritis management, 2 (2%) in whom avascular necrosis of the humeral ... developed on plain radiographs AbstractText: Arthroscopic management of native shoulder septicarthritis can yield alleviation of pain and a return to full ...
Muscular and Skeletal Diseases (5) Bacterial Arthritis (5), Infections (2), Necrosis (1), more mentions
Removal of infectedimplants and immediate autologous reconstruction is a safe single-stage procedure that preserves the native ... centre, retrospective proof-of-concept review of all salvage procedures performed for acute/chronic infected or exposed implant-based reconstructions by a single surgeon over a 6-year period AbstractText: We present ...
... the safety and effectiveness of minimally invasive distal metatarsal diaphyseal osteotomies (DMDOs) for treating a consecutive series of diabetic patients with chronic plantar diabeticfoot ulcers (CPDFUs) and second to assess their clinical-functional and radiographic outcomes AbstractText: A consecutive series of patients affected by diabetes mellitus with ... Keyword: diabeticfoot.
AbstractText: Limb salvage for diabeticfoot infections often require multiple procedures... save their leg if faced with a similar situation (p = 0.001) AbstractText: Most patients preferred to undergo multiple procedures to salvage the limb from diabeticfoot infection even if it ultimately concluded with a BKA... Keyword: Diabeticfoot infection.
Endocrine Disorders (4) Diabetic Foot (4), Infections (4), more mentions
... related to ulcer healing in people with a clinically infected diabeticfoot ulcer AbstractText: This multicentre, prospective, observational study reviewed participants' data at 12 months after culture of a diabeticfoot ulcer requiring antibiotic therapy ... Clinical outcomes at 12 months for people with an infected diabeticfoot ulcer are generally poor.
AbstractText: Outcomes of antibiotic treatment of diabeticfoot infections (DFIs) may depend not only on the antimicrobial susceptibility ... among isolates of Pseudomonas aeruginosa isolates cultured from specimens from diabeticfoot and other infections AbstractText: We examined 63 P. aeruginosa isolates ... phzS (p < .001) were statistically and significantly more common in diabeticfoot isolates, while plcH (p < .001) was significantly more common in ...
... here describe the main characteristics and the draft genome of Kocuria massiliensis sp. nov., strain P3598(T) (CSURP3598), a new Kocuria species that caused foot osteomyelitis in a 78-year-old woman... To the best of our knowledge, we report here the first case of osteomyelitis with a bacterial species from the genus Kocuria Keyword: 16S rRNA gene. Keyword: Genome.