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Urological Pharmacology
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Your search returned 20 results
from the time period: last 90 days.
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European urology 
Data on urothelial malignancies and UTUC were searched using the following keywords: urinary tract cancer; urothelial carcinomas; upper urinary tract, carcinoma; renal pelvis; ureter; bladder cancer; chemotherapy; ureteroscopy; nephroureterectomy; adjuvant treatment; instillation; recurrence; risk factors; and survival. References were weighted by a panel of experts AbstractText: Owing to the rarity of UTUC, there are insufficient data to provide strong recommendations ...
Urology (8), Oncology (4)
Carcinoma (6), Urologic Neoplasms (2), Urinary Bladder Neoplasms (1), more mentions
European urology
... view AbstractText: We reviewed available scientific studies to see if people with bacteria in their urine but without symptoms of urinary tract infection should be treated with antibiotics to eliminate bacteria... Antibiotic treatment did appear to benefit women in pregnancy and those about to undergo urological surgery Keyword: Antibiotic treatment.
Infectious Diseases (4), Urology (4), Endocrine Disorders (1)
Bacteriuria (3), Urinary Tract Infections (3), Infections (1), more mentions
Microbiome 
... mean relative abundance of Gardnerella vaginalis, Atopobium vaginae, and Sneathia amnii, while L. iners increased to levels twofold higher than those found in healthy women. Although individual urine microbial profiles strongly responded to the antibiotic, the healthy community could not be restored. The correlation between urinary and vaginal fluid microbiota was generally weak and depending on UT and BV status.
Infectious Diseases (4)
Bacterial Vaginosis (3), more mentions
The Journal of urology
Re: Cost-Effectiveness Analysis of Anticholinergics versus Botox for Urgency Urinary Incontinence: Results from the Anticholinergic versus Botox Comparison Randomized Trial..
Urology (2)
Urinary Incontinence (2), more mentions
Clinical toxicology (Philadelphia, Pa.)
We aimed to detect classical recreational drugs and NPS in the urine of music festival attendees and evaluate if the use of ... the analytical methods, limited specificity or cross-reactivity of the urine drug-screening immunoassays compared to UPLC-HR-TOFMS results AbstractText: Widespread uses of classical recreational drugs were identified in pooled urine samples ...
Annals of internal medicine 
AbstractText: Bone health is a significant concern in men with prostate cancer AbstractText: To evaluate the effectiveness of drug, supplement, and lifestyle interventions aimed at preventing fracture, improving bone mineral density (BMD), or preventing or delaying osteoporosis in men with nonmetastatic prostate cancer AbstractText: Ovid MEDLINE (1946 to 19 January ...
Muscular and Skeletal Diseases (7), Oncology (6)
Prostatic Neoplasms (6), Osteoporosis (1), more mentions
The Journal of urology
... a high disease burden who received the oral androgen receptor inhibitor enzalutamide in the PREVAIL (Safety and Efficacy Study of Oral MDV3100 in Chemotherapy-Naive Patients with Progressive Metastatic Prostate Cancer) study AbstractText: In this exploratory analysis low baseline prostate specific antigen was defined as less than 10 ng/ml ...
Oncology (6)
Prostatic Neoplasms (6), Neoplasms (1), more mentions
Drugs
Oral ulipristal acetate (Esmya(®); Fibristal(®)), a synthetic selective progesterone receptor modulator, is the first selective progesterone modulator to be approved for the treatment of uterine fibroids. It was initially approved for the preoperative treatment of moderate to severe uterine fibroid symptoms in women of reproductive age. Recently, the indication was extended in the EU to include the intermittent treatment of moderate to severe uterine fibroid symptoms. This narrative review summarizes pharmacological, efficacy and tolerability data relevant to the preoperative and intermittent use of ulipristal acetate in patients with symptomatic uterine fibroids. Ulipristal acetate is an effective and generally well tolerated treatment for patients with symptomatic uterine fibroids, both as preoperative, single-course treatment and as intermittent, longer-term treatment. It is noninferior in efficacy to intramuscular leuprolide acetate, as a preoperative treatment, and is associated with a lower rate of hot flashes, a common adverse event with gonadotropin-releasing hormone analogues. Thus, ulipristal acetate is an effective option for both preoperative and intermittent treatment of moderate to severe, symptomatic uterine fibroids in women of reproductive age.
Fibroid Uterus (7), more mentions
Pharmacotherapy
In this review, we describe current therapies for mCRPC, the rationale for anti-PARP therapies, the pharmacology of olaparib for prostate cancer, clinical trials of olaparib for mCRPC, our clinical experience with olaparib for prostate cancer at a comprehensive cancer center, and future directions of olaparib for the treatment of ...
Oncology (9)
Prostatic Neoplasms (8), Neoplasms (1), more mentions
Lancet (London, England)
Since the first coronary angioplasty on Sept 16, 1977, the field of percutaneous coronary intervention has evolved rapidly. Now marking its 40th anniversary, percutaneous coronary intervention has become one of the most common medical procedures worldwide. Much of this progress has been due to the iteration and improvement of angioplasty technologies. Balloon angioplasty was limited by unpredictable procedural outcomes due to vessel dissection and recoil, and a high rate of restenosis. The introduction of stents resulted in more stable early results and lower rates of restenosis, although early stent thrombosis and neointimal hyperplasia causing vessel renarrowing were key limitations. Drug-eluting stents delivering antiproliferative agents significantly lowered the rates of restenosis, permitting widespread use of percutaneous coronary intervention in more advanced and complex disease. Although fully bioresorbable scaffolds have the potential to further improve long-term outcomes, they have not yet achieved results equivalent to those of conventional metallic drug-eluting stents in the early years after implantation. Progress in catheter technology did not occur in isolation, and the success of percutaneous coronary intervention is also due to important advances in intracoronary imaging, and adjunct pharmacotherapy-each of which is reviewed in other papers in this Series.
Thrombosis (1), Hyperplasia (1), more mentions
The Journal of urology
AbstractText: Enzalutamide significantly prolonged median progression-free survival vs bicalutamide in chemotherapy-naïve metastatic castration-resistant prostate cancer in TERRAIN. A post hoc analysis investigated the influence of age on efficacy and safety of enzalutamide vs bicalutamide in this population AbstractText: Patients were randomized 1:1 to enzalutamide 160 mg/day or bicalutamide 50 mg/day.
Oncology (3), Urology (1), Cardiovascular Diseases (1)
Prostatic Neoplasms (3), Urinary Tract Infections (1), Atrial Fibrillation (1), more mentions
Pharmacotherapy
Abstract: Limited evidence supports use of oral antibiotics for Enterobacteriaceae-associated bacteremic urinary tract infection. This retrospective cohort study found no statistically significant difference in the composite outcome of treatment failure in patients who received exclusively intravenous versus intravenous/oral antibiotics for the treatment of bacteremic urinary tract infections. This article is protected by copyright.
Urology (4), Infectious Diseases (4)
Urinary Tract Infections (4), Bacteremia (1), more mentions
JAMA internal medicine 
Control PCCs received electronic decision tools only AbstractText: Primary outcomes included documentation of guideline-concordant care (both a patient-PCC agreement in the electronic health record and at least 1 urine drug test [UDT]) over 12 months and 2 or more early opioid refills. Secondary outcomes included opioid dose reduction (ie, 10% decrease in morphine-equivalent daily dose [MEDD] at ...
European urology
AbstractText: In advanced prostate cancer (APC), successful drug development as well as advances in imaging and molecular characterisation have resulted in multiple areas where there is lack of ... targeted therapy; molecular characterisation of blood and tissue; genetic counselling/testing; side effects of systemic treatment(s); global access to prostate cancer drugs.
Oncology (17)
Prostatic Neoplasms (17), more mentions
Clinical toxicology (Philadelphia, Pa.)
AbstractText: To compare user self-identification of nonpharmaceutical fentanyl exposure with confirmatory urine drug testing in emergency department (ED) patients presenting after heroin overdose AbstractText: This was a cross-sectional study of adult ED patients who presented after a heroin overdose requiring ... Naloxone was detected in all urine drug screens.
Men's Health (3), more mentions
16. Levetiracetam in toxic seizures.  
Date: 07/28/2017
Clinical toxicology (Philadelphia, Pa.)
... by ICD-9 codes based on the following: (1) a poisoning diagnosis, (2) a seizure diagnosis, and (3) administration of LEV. We included patients with a drug-induced seizure based on history, electroencephalogram results, blood alcohol concentrations, urine drug screens, and adequate documentation. We excluded patients with alcohol withdrawal, anoxic brain injury, subtherapeutic concentrations of other antiepileptics, hypoglycemia, and pseudoseizures.
Seizures (19), Tonic-Clonic Seizures (1), Status Epilepticus (1), more mentions
Infection control and hospital epidemiology
Abstract: We assessed multidrug-resistant organism (MDRO) patient hand colonization in relation to the environment in post-acute care to determine risk factors for MDRO hand colonization. Patient hand colonization was significantly associated with environmental contamination. Risk factors for hand colonization included disability, urinary catheter, recent antibiotic use, and prolonged hospital stay. Infect Control Hosp Epidemiol 2017;38:1110-1113.
Infectious Diseases (1), more mentions
Drug and alcohol dependence
... controversial, with very scant literature in Black adults AbstractText: The current study determined the differences in the lymphocyte count, specifically the number cluster differentiation 4 and 8 (CD4+ and CD8+), among patients who urine drug tested negative for THC (n=70) and those who tested positive for THC (n=25.
Drug and alcohol dependence
... physicians into low- (lower 50%), moderate- (51-89%) and high-volume (top 10%) prescribers. We summarized the distribution of OMT prescription days dispensed and urine drug screens (UDS) ordered using Lorenz curves and examined physician characteristics using descriptive statistics AbstractText: We identified 893 OMT prescribers in 2014. Physicians were mostly male (67.5%; N=603), and middle-aged (median was 50.
20. Bruises on the ears and body.  
Date: 09/01/2017
The Journal of family practice
... visit, her vitals and physical examination were unremarkable, apart from the skin findings. Her complete blood count, complete metabolic panel, and urinalysis were unremarkable. On her previous admissions, the patient's urine drug test had been positive for cocaine. She'd also tested positive for cytoplasmic antineutrophil cytoplasmic antibodies, antinuclear antibodies, anti-double stranded DNA, and anticardiolipin IgM. WHAT IS YOUR DIAGNOSIS.
Men's Health (2)
Deep Vein Thrombosis (1), Cocaine Abuse (1), more mentions