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Top Articles Across Gastroenterology
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Your search returned 10 results
from the time period: last 30 days.
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Journal of hepatology 
AbstractText: Little is known about the association between non-alcoholic fatty liver disease (NAFLD) and cancer development... NAFLD was diagnosed by ultrasonographic detection of hepatic steatosis in the absence of other known liver disease, including alcoholic or viral hepatitis ... score showed a strong association with the development of all cancers and HCC AbstractText: Non-alcoholic fatty liver disease (NAFLD) is associated with developing hepatocellular carcinoma (HCC ...
Oncology (13), Infectious Diseases (1)
Neoplasms (7), Fibrosis (5), Colorectal Neoplasms (3), more mentions
Hepatology (Baltimore, Md.) 
... alcohol risk use are both associated with high prevalence of hepatic steatosis, but only a minority develop liver failure or liver cancer ... as additional independent predictors AbstractText: Multiple components of the metabolic syndrome independently affected the risk for severe liver disease... alcohol consumption was within the limits currently defining non-alcoholic fatty liver disease.
Endocrine Disorders (3), Oncology (2)
Liver Diseases (4), Diabetes Mellitus (3), Liver Neoplasms (2), more mentions
Diabetes care 
Eighty-five and 1,589 subjects who developed pancreatic cancer were registered among the incretin and NIAD new users, respectively, which represented an aHR of pancreatic cancer of 2.14 (95% CI 1.71-2.67) among those prescribed an ... The risk of pancreatic cancer among patients subsequently prescribed insulin was 6.89 (6.05-7.85) AbstractText: The recent prescription of incretin therapy is associated with an increased risk of pancreatic cancer ...
Oncology (11), Endocrine Disorders (3)
Pancreatic Neoplasms (11), Diabetes Mellitus (3), more mentions
Cell reports 
... adult hematopoiesis, but the underlying molecular events governing these processes remain incompletely understood. Here, we identified robust expression of the leukemia-associated transcription factor hepatic leukemia factor (Hlf) in normal multipotent hematopoietic progenitors, which was rapidly downregulated upon differentiation. Interference with its normal downregulation revealed Hlf as a strong negative regulator of lymphoid development, while remaining compatible with myeloid fates.
Oncology (3)
Leukemia (3), more mentions
Lancet (London, England) 
Eliminating viral hepatitis: time to match visions with action..
Infectious Diseases (2)
Hepatitis (2), more mentions
The New England journal of medicine 
Abnormalities of hepatic function occurred in 5 patients in each fremanezumab group (1%) and 3 patients in the placebo group ( <1%) AbstractText: Fremanezumab as a preventive treatment for chronic migraine resulted in a lower frequency of headache than placebo in this 12-week trial. Injection-site reactions to the drug were common.
Pain Management (7)
Headache (8), Migraine Disorders (7), more mentions
The Cochrane database of systematic reviews 
AbstractText: Percutaneous exposure injuries from devices used for blood collection or for injections expose healthcare workers to the risk of blood borne infections such as hepatitis B and C, and human immunodeficiency virus (HIV. Safety features such as shields or retractable needles can possibly contribute to the prevention of these injuries and it is important to evaluate their effectiveness AbstractText ...
Infectious Diseases (1), Immune System Diseases (1)
Infections (2), Hepatitis B (1), more mentions
Proceedings of the National Academy of Sciences of the United States of America 
In contrast to Escherichia coli, a model organism for chemotaxis that has 5 chemoreceptors and a single chemosensory pathway, Pseudomonas aeruginosa PAO1 has a much more complex chemosensory network, which consists of 26 chemoreceptors feeding into four chemosensory pathways. While several chemoreceptors were rigorously linked to specific pathways in a series of experimental studies, for most of them this information is not available. Thus, we addressed the problem computationally. Protein-protein interaction network prediction, coexpression data mining, and phylogenetic profiling all produced incomplete and uncertain assignments of chemoreceptors to pathways. However, comparative sequence analysis specifically targeting chemoreceptor regions involved in pathway interactions revealed conserved sequence patterns that enabled us to unambiguously link all 26 chemoreceptors to four pathways. Placing computational evidence in the context of experimental data allowed us to conclude that three chemosensory pathways in P. aeruginosa utilize one chemoreceptor per pathway, whereas the fourth pathway, which is the main system controlling chemotaxis, utilizes the other 23 chemoreceptors. Our results show that while only a very few amino acid positions in receptors, kinases, and adaptors determine their pathway specificity, assigning receptors to pathways computationally is possible. This requires substantial knowledge about interacting partners on a molecular level and focusing comparative sequence analysis on the pathway-specific regions. This general principle should be applicable to resolving many other receptor-pathway interactions.
The Lancet. Haematology 
One patient died in the experimental group (from hepatic veno-occlusive disease after an allogeneic haemopoietic stem-cell transplantation) and three died in the control group (one from multiorgan failure, one from invasive pulmonary aspergillosis, and one from a post-chemotherapy intestinal perforation) AbstractText: In high-risk patients with haematological ...
Neutropenia (4), Mucositis (1), Intestinal Perforation (1), more mentions
The lancet. Gastroenterology & hepatology 
... intravenous acetylcysteine treatment for paracetamol overdose had circulating biomarkers measured at hospital presentation. The primary endpoint was acute liver injury indicating need for continued acetylcysteine treatment beyond the standard course (alanine aminotransferase [ALT] activity >100 U/L... This prospective study supports their use for hepatic safety assessment of new medicines AbstractText: Edinburgh and Lothians Health Foundation, UK Medical Research Council.