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Top Articles Across Endocrinology
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Your search returned 24 results
from the time period: last 30 days.
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The New England journal of medicine 
Abstract: Background Combination treatment with the cystic fibrosis transmembrane conductance regulator (CFTR) modulators tezacaftor (VX-661) and ivacaftor ... to target the underlying cause of disease in patients with cystic fibrosis... in patients 12 years of age or older who had cystic fibrosis and were homozygous for the CFTR Phe508del mutation.
Cystic Fibrosis (5), more mentions
The risk of AF is increased in subclinical hyperthyroidism, but it is uncertain whether variations in thyroid function within the normal range or subclinical hypothyroidism are also associated with AF ... The euthyroid state was defined as thyroid-stimulating hormone (TSH) 0.45 to 4.49 mIU/L, and subclinical hypothyroidism as TSH 4.5 to 19.9 mIU/L with free thyroxine ...
Cardiovascular Diseases (4)
Hypothyroidism (6), Atrial Fibrillation (3), Heart Failure (1), more mentions
The New England journal of medicine 
AbstractText: The administration of endocrine therapy for 5 years substantially reduces recurrence rates during and after ... 62,923 women with ER-positive breast cancer who were disease-free after 5 years of scheduled endocrine therapy, we used Kaplan-Meier and Cox regression analyses, stratified according ... 22%, and 26%, respectively AbstractText: After 5 years of adjuvant endocrine therapy, breast-cancer recurrences continued to occur steadily throughout the study ...
Oncology (10)
Neoplasms (8), Breast Neoplasms (6), more mentions
BMJ open diabetes research & care 
It is unknown whether statins similarly modify diabetes risk in higher risk populations AbstractText: During the Diabetes Prevention Program Outcomes Study (n=3234), the long-term follow ... a randomized clinical trial of interventions to prevent T2DM, incident diabetes was assessed by annual 75 g oral glucose tolerance testing ... This risk was not materially altered by adjustment for baseline diabetes risk factors and potential confounders related to indications for statin therapy AbstractText: In this population at high risk for diabetes, we observed significantly higher rates of diabetes with statin therapy in all three treatment groups ...
Endocrine Disorders (17), Cardiovascular Diseases (13)
Diabetes Mellitus (16), Diabetes Mellitus, Type 2 (1), Cardiovascular Diseases (1), more mentions
Lancet (London, England) 
AbstractText: Infected necrotising pancreatitis is a potentially lethal disease and an indication for invasive intervention. The surgical step-up approach is the standard treatment. A promising alternative is the endoscopic step-up approach. We compared both approaches to see whether the endoscopic step-up approach was superior to the surgical step-up approach in terms of clinical and economic outcomes ...
Pancreatitis (4), Pancreatic Fistula (1), Necrosis (1), more mentions
The Cochrane database of systematic reviews 
AbstractText: Polycystic ovary syndrome (PCOS) is a common endocrine condition, affecting approximately one in 10 women... Long-term health concerns include an increased risk of heart disease, diabetes and the development of precancerous disease of the womb AbstractText: To assess the effectiveness and harms of ovarian surgery as a treatment ...
Cardiovascular Diseases (1), Endocrine Disorders (1), Anti-Obesity and Weight Loss (1)
Acne Vulgaris (6), Hirsutism (5), Polycystic Ovary Syndrome (2), more mentions
Diabetes care 
... this trial was to investigate whether additional HBOT would benefit patients with diabetes and ischemic leg ulcers AbstractText: Patients with diabetes with an ischemic wound (n = 120) were randomized to standard care (SC ... not significantly improve complete wound healing and limb salvage in patients with diabetes and lower limb ischemia.
Endocrine Disorders (4)
Diabetes Mellitus (4), Leg Ulcer (2), Ischemia (1), more mentions
JAMA internal medicine 
... evaluated lifestyle modification (LSM) and medication interventions (>6 months) for diabetes prevention in adults (age ≥18 years) at risk for diabetes, reporting between-group differences in diabetes incidence, published between January 1, 1990, and January 1, 2015 ... bariatric surgery, as well as those involving participants with gestational diabetes, type 1 or 2 diabetes, and metabolic syndrome, were excluded AbstractText: Reviewers extracted the number of diabetes cases at the end of active intervention in treatment and ...
Endocrine Disorders (14), Anti-Obesity and Weight Loss (1)
Diabetes Mellitus (13), Diabetes Mellitus, Type 1 (1), Prediabetic State (1), more mentions
Annals of internal medicine 
... clinical diagnostic criteria AbstractText: To provide national estimates of undiagnosed diabetes by using a confirmatory testing strategy, in line with clinical ... S. adults aged 20 years and older AbstractText: Confirmed undiagnosed diabetes was defined as elevated levels of fasting glucose (≥7.0 mmol ... mg/dL]) and hemoglobin A1c (≥6.5%) in persons without diagnosed diabetes AbstractText: The prevalence of total (diagnosed plus confirmed undiagnosed) diabetes increased from 5.5% (9.7 million adults) in 1988 to 1994 ...
Endocrine Disorders (15), Anti-Obesity and Weight Loss (2), Kidney Disease (1)
Diabetes Mellitus (15), Kidney Diseases (1), more mentions
JAMA oncology 
AbstractText: Although patients with resected pancreatic adenocarcinoma are at high risk for disease recurrence, few biomarkers are available to inform patient outcomes AbstractText ... immunohistochemistry and next-generation sequencing in formalin-fixed, paraffin-embedded tumors in 356 patients with resected pancreatic adenocarcinoma who were treated at the Dana-Farber/Brigham and ...
Oncology (3)
Neoplasms (9), Adenocarcinoma (6), more mentions
... myocardial infarction, or nonfatal stroke in patients with type 2 diabetes mellitus and elevated cardiovascular risk... Assessment Study) randomly assigned 10 142 participants with type 2 diabetes mellitus to canagliflozin or placebo... female (45% versus 31%), and had a longer duration of diabetes mellitus (14 versus 13 years) compared with secondary prevention participants (N ...
Endocrine Disorders (5), Cardiovascular Diseases (3)
Diabetes Mellitus, Type 2 (3), Heart Failure (2), Myocardial Infarction (2), more mentions
Methods : We performed a population-based cohort study among type 2 diabetes patients with established cardiovascular disease newly initiated on antihyperglycemic agents (AHAs) within the US Department of Defense ... the class of medication as the study was not powered to make comparisons among individual treatments Keyword: diabetes mellitus. Keyword: diabetic therapy.
Cardiovascular Diseases (2), Endocrine Disorders (2)
Heart Failure (2), Diabetes Mellitus, Type 2 (1), Myocardial Infarction (1), more mentions
The Cochrane database of systematic reviews 
... serious adverse events such as hypercalcaemia (RR 5.00, 95% CI 0.25 to 100.8; 1 trial; 76 participants), myocardial infarction (RR 0.75, 95% CI 0.08 to 6.81; 2 trials; 86 participants), and thyroiditis (RR 0.33 95% CI 0.01 to 7.91; 1 trial; 68 participants) is uncertain because the results were imprecise.
Infectious Diseases (1)
Liver Diseases (5), Glossitis (1), Thyroiditis (1), more mentions
... related cardiac index to regional CBF, with adjustment for age, education, race/ethnicity, Framingham Stroke Risk Profile score (systolic blood pressure, antihypertensive medication use, diabetes mellitus, current cigarette smoking, left ventricular hypertrophy, prevalent cardiovascular disease [CVD], atrial fibrillation), APOE ε4 status, cognitive diagnosis, and regional tissue volume AbstractText: Lower cardiac ...
Neuroscience (3), Cardiovascular Diseases (3), Endocrine Disorders (1)
Heart Failure (2), Atrial Fibrillation (2), Dementia (2), more mentions
... sources of information were identified with PubMed/Medline and online sources from the Centers for Disease Control and Prevention AbstractText: The higher prevalence of traditional cardiovascular risk factors (eg, hypertension, diabetes mellitus, obesity, and atherosclerotic cardiovascular risk) underlies the relatively earlier age of onset of cardiovascular diseases among African Americans.
Cardiovascular Diseases (7), Endocrine Disorders (1), Anti-Obesity and Weight Loss (1)
Cardiovascular Diseases (5), Heart Failure (2), Hypertension (2), more mentions
For example, the increase in annual diabetes spending between 1996 and 2013 was $64.4 (UI, $57.9-$70.6) billion; $44.4 (UI, $38.7-$49.6) billion of this increase was pharmaceutical spending AbstractText: Increases in US health care spending from 1996 through 2013 were largely related to increases in health care service price ...
Endocrine Disorders (1)
Diabetes Mellitus (1), more mentions
BMJ (Clinical research ed.) 
... 045), and the mean research payment was $37 963 (SD $175 239. The highest median general payments were received by journal editors from endocrinology ($7207, $0-85 816), cardiology ($2664, $0-12 912), gastroenterology ($696, $0-20 002), rheumatology ($515, $0-14 280), and urology ($480, $90-669. For high impact general medicine journals, median payments were $0 ($0-14.
Urology (1), Muscular and Skeletal Diseases (1), more mentions
The response to the interventions on the gut microbiome composition and insulin sensitivity as well on measures of glucose and lipid metabolism, gut functionality, inflammatory markers, anthropometry and urine metabolomics were assessed AbstractText: 50 participants completed both periods with a whole grain intake of 179±50 g/day and 13 ...
Anti-Obesity and Weight Loss (1)
Insulin Sensitivity (3), Obesity (1), more mentions
Hypertension (Dallas, Tex. : 1979) 
Keyword: ACC/AHA Clinical Practice Guidelines. Keyword: Systems of care. Keyword: ambulatory care. Keyword: antihypertensive agents. Keyword: behavior modification. Keyword: blood pressure. Keyword: chronic kidney disease. Keyword: diabetes. Keyword: hypertension. Keyword: hypertension emergency. Keyword: lifestyle measures. Keyword: measurement. Keyword: nonpharmacologic treatment. Keyword: resistant hypertension. Keyword: risk reduction. Keyword: secondary hypertension.
Cardiovascular Diseases (5), Endocrine Disorders (1), Kidney Disease (1)
Hypertension (5), Chronic Kidney Diseases (1), Diabetes Mellitus (1), more mentions
Nature ecology & evolution 
These varying selection patterns concur with anthropological evidence of varying diets, and with the association of farming-adaptive alleles with higher FADS1 expression and thus enhanced LCPUFA biosynthesis. Genome-wide association studies reveal that farming-adaptive alleles not only increase LCPUFAs, but also affect other lipid levels and protect against several inflammatory diseases.
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