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Gynecologic Oncology
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Your search returned 22 results
from the time period: last 90 days.
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BMJ supportive & palliative care 
... improved cancer-specific quality of life for women following curative treatment for stage I-III gynaecological cancer AbstractText: Consecutive women were invited to participate in a randomised controlled study (HNA and care ... professional is cost-effective, acceptable and useful for some women treated for stage I-III gynaecological cancer... Keyword: gynaecological cancer.
Oncology (9)
Neoplasms (9), more mentions
Lancet (London, England) 
... poly(ADP-ribose) polymerase inhibitor, has anticancer activity in recurrent ovarian carcinoma harbouring a BRCA mutation or high percentage of genome-wide ... based chemotherapy in patients with high-grade, recurrent, platinum-sensitive ovarian carcinoma AbstractText: In this randomised, double-blind, placebo-controlled, phase 3 ... sensitive, high-grade serous or endometrioid ovarian, primary peritoneal, or fallopian tube carcinoma, had received at least two previous platinum-based chemotherapy regimens ...
Oncology (5)
Carcinoma (7), Ovarian Neoplasms (2), Neoplasms (2), more mentions
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 
DescriptorName: Ovarian Neoplasms... Abstract: Purpose Platinum-based chemotherapy (PBC) for patients with progressing ovarian cancer (OC) is more effective with a longer time interval from previous platinum treatment (platinum-free interval [PFI. In 1999, it was hypothesized that prolonging PFI with single-agent non-PBC (NPBC) may offer a strategy to improve overall outcome.
Oncology (3)
Ovarian Neoplasms (3), Neoplasms (1), more mentions
The Cochrane database of systematic reviews 
The role of lymphadenectomy in surgical management of endometrial cancer remains controversial... FIGO (International Federation of Gynaecology and Obstetrics) staging system for endometrial cancer... treat possible lymph node metastases in women with early-stage endometrial cancer found no survival advantage... the effectiveness and safety of lymphadenectomy for the management of endometrial cancer AbstractText: We searched the Cochrane Central Register of Controlled Trials ...
Oncology (7)
Endometrial Carcinoma (6), Neoplasms (1), more mentions
International journal of nursing studies 
AbstractText: High levels of fatigue have been documented in ovarian cancer patients... led home-based exercise and cognitive behavioral therapy (E&CBT) for ovarian cancer adults with cancer-related fatigue on outcomes of fatigue, plus ... primary cancer treatment AbstractText: Randomized, single-blind control trial AbstractText: Gynaecologic oncology department of the First Hospital of Jilin University in China ...
Oncology (11), Neuroscience (7)
Ovarian Neoplasms (5), Neoplasms (5), more mentions
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 
Abstract: Purpose In the United States, 3.8 million women have a history of breast (BC) or ovarian cancer (OC. Up to 15% of cases are attributable to heritable mutations, which, if identified, provide critical knowledge for treatment and preventive care. It is unknown how many patients who are at high risk for these mutations have not been tested and how ...
Oncology (5)
Neoplasms (3), Ovarian Neoplasms (2), more mentions
Nature communications 
Abstract: High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of ovarian cancer and has a poor outcome ... It has been proposed that fallopian tube cancers may be precursors of HGSOC but evolutionary evidence for this ... tube lesions (p53 signatures, serous tubal intraepithelial carcinomas (STICs), and fallopian tube carcinomas), ovarian cancers, and metastases from nine patients.
Oncology (2)
Carcinoma (5), Ovarian Neoplasms (2), Neoplasms (1), more mentions
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 
Here, we present the results from the cohort of patients with advanced cervical cancer... Results Twenty-four patients were enrolled in the cervical cancer cohort... Conclusion In patients with programmed death ligand 1-positive advanced cervical cancer, pembrolizumab demonstrated antitumor activity and exhibited a safety profile consistent with that seen ...
Oncology (4)
Uterine Cervical Neoplasms (4), Neoplasms (3), more mentions
The Journal of experimental medicine 
... these phenotypes via CD55, an intrinsic cell surface complement inhibitor, which was identified in a comparative analysis between CSCs and non-CSCs in endometrioid cancer models... node that drives self-renewal and therapeutic resistance through a bifurcating signaling axis and provides an opportunity to target both signaling pathways in endometrioid tumors.
Oncology (2)
Neoplasms (4), more mentions
JAMA oncology 
... tumor-infiltrating lymphocytes (TILs) participate in immune control of epithelial ovarian cancer; however, little is known about prognostic patterns of CD8+ TILs ... To define the prognostic role of CD8+ TILs in epithelial ovarian cancer AbstractText: This was a multicenter observational, prospective survival cohort study of the Ovarian Tumor Tissue Analysis Consortium ...
Oncology (4)
Neoplasms (5), Ovarian Neoplasms (3), Mucinous Adenocarcinoma (1), more mentions
Cell 
DescriptorName: Ovarian Neoplasms... Abstract: We present an exceptional case of a patient with high-grade serous ovarian cancer, treated with multiple chemotherapy regimens, who exhibited regression of some metastatic lesions with concomitant progression of other lesions during a treatment-free period. Using immunogenomic approaches, we found that progressing metastases were characterized by immune cell exclusion, whereas regressing and stable metastases ...
Oncology (5)
Neoplasms (5), Ovarian Neoplasms (3), Neoplasm Metastasis (1), more mentions
Proceedings of the National Academy of Sciences of the United States of America 
... enabled us to exhaustively characterize the immunopeptidomic landscape of epithelial ovarian cancers (EOCs... a variety of benign sources has unveiled a multitude of ovarian cancer antigens (MUC16, MSLN, LGALS1, IDO1, KLK10) to be presented by HLA class I and class II molecules exclusively on ovarian cancer cells ... Keyword: ovarian cancer.
Oncology (5)
Ovarian Neoplasms (3), Neoplasms (2), Carcinoma (1), more mentions
Nature communications 
Many high-grade serous carcinomas (HGSCs) of the pelvis are thought to originate in the distal portion of the fallopian tube. Serous tubal intra-epithelial carcinoma (STIC) lesions are the putative precursor to HGSC and identifiable in ~ 50% of advanced stage cases. To better understand the molecular etiology of HGSCs, we report a multi-center integrated genomic analysis of advanced stage tumors with and without STIC lesions and normal tissues. The most significant focal DNA SCNAs were shared between cases with and without STIC lesions. The RNA sequence and the miRNA data did not identify any clear separation between cases with and without STIC lesions. HGSCs had molecular profiles more similar to normal fallopian tube epithelium than ovarian surface epithelium or peritoneum. The data suggest that the molecular features of HGSCs with and without associated STIC lesions are mostly shared, indicating a common biologic origin, likely to be the distal fallopian tube among all cases.High-grade serous carcinomas (HGSCs) are associated with precursor lesions (STICs) in the fallopian epithelium in only half of the cases. Here the authors report the molecular analysis of HGSCs with and without associated STICs and show similar profiles supporting a common origin for all HGSCs.
Carcinoma (5), Neoplasms (1), more mentions
International journal of cancer 
During a median follow up of 11.5 years, 2,598 cases of prostate cancer (including 287 advanced cases) have been identified among 27,004 men in the intervention arm of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Dietary intake of phytoestrogens (excluding lignans) was assessed with a food frequency questionnaire.
Oncology (11)
Prostatic Neoplasms (8), Ovarian Neoplasms (2), Neoplasms (1), more mentions
Obstetrics and gynecology 
... of care during the first year after a diagnosis of ovarian cancer, estimate the sources of cost, and explore the out-of ... AbstractText: We performed a retrospective cohort study of women with ovarian cancer diagnosed from 2009 to 2012 who underwent both surgery and ... cost of care within the first year of diagnosis of ovarian cancer; secondary outcomes included assessment of factors associated with cost AbstractText: A total of 26,548 women with ovarian cancer who underwent surgery were identified ...
Oncology (6)
Ovarian Neoplasms (6), more mentions
Clinical cancer research : an official journal of the American Association for Cancer Research 
... adjusted HR, 0.30; 95% CI, 0.13-0.68; p=0.004) and 5-year OS (78%; adjusted HR, 0.09; 95% CI, 0.02-0.38; p=0.001) AbstractText: Among ovarian cancer patients, BRCA2 carriers with mutations located in the RAD51-BD (exon 11) have prolonged progression-free survival, platinum-free interval and overall survival.
Oncology (3)
Ovarian Neoplasms (2), Neoplasms (1), more mentions
eLife 
Abstract: Recent studies posit a role for non-coding RNAs in epithelial ovarian cancer (EOC... 454 patients with various diagnoses, the miRNA neural network had 100% specificity for ovarian cancer... suggest circulating miRNAs have potential to develop a non-invasive diagnostic test for ovarian cancer Keyword: cancer biology... Keyword: ovarian cancer.
Oncology (6)
Ovarian Neoplasms (5), Neoplasms (1), more mentions
Obstetrics and gynecology 
... between use of an intrauterine device (IUD) and risk of cervical cancer by subjecting existing data to critical review, quantitative synthesis, and ... individual-level measures of use of an IUD and incident cervical cancer... protective effect, which may be stronger in populations with higher cervical cancer incidence AbstractText: Invasive cervical cancer may be approximately one third less frequent in women who ...
Oncology (9)
Uterine Cervical Neoplasms (9), more mentions
JAMA oncology 
Trends in Breast, Colorectal, and Cervical Cancer Incidence Following the Affordable Care Act: Implications for Cancer Screening..
Oncology (4)
Uterine Cervical Neoplasms (2), Neoplasms (2), more mentions
Journal of global oncology 
Abstract: Cervical cancer incidence and mortality rates are significantly higher in low- and middle-income countries compared with the United ... are also found in underserved areas of the United States, such as the Texas-Mexico border, where cervical cancer mortality rates are 30% higher than in the rest of Texas.
Oncology (5)
Uterine Cervical Neoplasms (3), Neoplasms (1), Breast Neoplasms (1), more mentions
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