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Asthma and Lower Airway Disease
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Asthma is a chronic inflammatory disorder of the airways associated with airway hyperresponsivenes, which leads to recurrent wheezing, coughing, and difficulty breathing. Variable, reversible airflow obstruction is a hallmark of asthma. Reversibility can either be spontaneous or with treatment. Asthma exacerbations are periods of worsening symptoms between periods of relative symptom stability. From the Washington Manual of Allergy, Asthma, and Immunology Subspecialty Consult.

Your search returned 12 results
from the time period: last 90 days.
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The New England journal of medicine 
CitationSubset: AIM. CitationSubset: IM. DescriptorName: Asthma. DescriptorName: Cytokines. DescriptorName: Humans. DescriptorName: Lung.
Asthma (2), more mentions
Lancet (London, England) 
Since macrolide antibiotics can be used to treat persistent asthma, we aimed to assess the efficacy and safety of oral ... azithromycin as add-on therapy in patients with uncontrolled persistent asthma on medium-to-high dose inhaled corticosteroids plus a long ... trial to determine whether oral azithromycin decreases the frequency of asthma exacerbations in adults (≥18 years) with symptomatic asthma despite current use of inhaled corticosteroid and long-acting bronchodilator ...
Infectious Diseases (1)
Asthma (16), Hearing Loss (1), more mentions
The New England journal of medicine 
... the sputum and disease progression that are characteristic of chronic bronchitis AbstractText: We characterized the COPD status of 917 participants from ... association between total mucin concentration and a diagnosis of chronic bronchitis yielded areas under the curve of 0.72 (95% confidence interval ... mucin concentrations may quantitate a key component of the chronic bronchitis pathophysiologic cascade that produces sputum and mediates disease severity.
Chronic Obstructive Pulmonary Disease (6), Chronic Bronchitis (5), Bronchitis (1), more mentions
4. Eosinophilic Bronchitis.  
Date: 08/30/2017
The New England journal of medicine 
CitationSubset: AIM. CitationSubset: IM. DescriptorName: Adult. DescriptorName: Bronchi. DescriptorName: Bronchitis. DescriptorName: Bronchoscopy. DescriptorName: Eosinophilia. DescriptorName: Eosinophils. DescriptorName: Female. DescriptorName: Humans.
Bronchitis (2), Eosinophilia (1), more mentions
American journal of respiratory and critical care medicine 
... Endobronchial Valve (EBV) treatment have demonstrated benefit in severe heterogeneous emphysema... efficacy and safety of Zephyr EBVs in patients with heterogeneous emphysema and absence of collateral ventilation AbstractText: Prospective, multicenter 2:1 ... EBV subjects AbstractText: EBV treatment in hyperinflated patients with heterogeneous emphysema without collateral ventilation resulted in clinically meaningful benefits in lung ...
Emphysema (4), Dyspnea (2), Pneumothorax (1), more mentions
The New England journal of medicine 
AbstractText: In some patients with moderate-to-severe asthma, particularly those with noneosinophilic inflammation, the disease remains uncontrolled... The primary end point was the annualized rate of asthma exacerbations (events per patient-year) at week 52 AbstractText: The ... every 2 weeks (high dose; 146 patients) resulted in annualized asthma exacerbation rates at week 52 of 0.26, 0.19, and 0.22 ...
Asthma (6), more mentions
The New England journal of medicine 
Severe and Difficult-to-Treat Asthma in Adults..
Asthma (2), more mentions
ERJ open research 
The aim of this service improvement project was to gain understanding of the patient experience of lung volume reduction surgery (LVRS) and endobronchial valve (EBV) placement, from referral through to post-discharge care. Focus group interviews were carried out in two tertiary centres in London and Leicester, UK. Sixteen patients who had undergone lung volume reduction surgery (LVRS), endobronchial valve (EBV) placement, or both, were recruited. Prior to participation in each focus group, participants completed a questionnaire to guide and focus discussion. Thematic analysis identified common themes to the participant experience of receiving lung volume reduction interventions. Themes included patient focus on declining health and the need to "fight" for a referral; consequences of having procedures and potential unexpected complications; and vulnerability post discharge and limited continuity of care. Participants were clear that the benefits of having had either LVRS or EBV procedures outweighed any difficulties experienced. Participants were keen to have further similar interventions if appropriate. These data confirm the need to develop more systematic lung volume reduction pathways, provide appropriate information, and ensure that post-discharge care is optimal.
Emphysema (1), more mentions
9. Severe asthma and quality of life.  
Date: 08/31/2017
The World Allergy Organization journal 
Abstract: Severe asthma has a great impact on the quality of life (QOL ... Appropriate asthma control and modifications of social roles and activities are expected ... target specific pathways and molecules important in the pathogenesis of asthma... promising effects on the QOL of patients with severe recalcitrant asthma... This article briefly reviews the impact of severe asthma on QOL and the potential methods to combat this morbidity ...
Asthma (7), more mentions
The Lancet. Respiratory medicine 
COPD and asthma: the emergency is clear, now is the time for action..
Asthma (2), more mentions
The Lancet. Respiratory medicine 
... as the reference for COPD and a reported diagnosis of asthma with current wheeze as the definition of asthma... Smoking and occupational asthmagens were the only risks quantified for asthma in GBD, accounting for 16·5% (14·6 to 18·7) of DALYs due to asthma AbstractText: Asthma was the most prevalent chronic respiratory disease worldwide in 2015 ...
Chronic Obstructive Pulmonary Disease (20), Asthma (19), more mentions
Frontiers in immunology 
Inflammatory bowel diseases (IBD) and asthma are chronic mucosal inflammatory conditions of unknown etiology with increasing prevalence worldwide... While asthma is a disease of the airways, increasing evidence indicates a link between the gut ... responses and the microbiota and how these can influence the pathology of IBD and asthma Keyword: asthma.
Endocrine Disorders (1), Anti-Obesity and Weight Loss (1)
Asthma (4), Inflammatory Bowel Diseases (2), Obesity (1), more mentions