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Upper Respiratory Infections
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Your search returned 75 results
from the time period: last 90 days.
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The Journal of infectious diseases
AbstractText: Data on the relative contribution of influenza virus and other respiratory pathogens to respiratory infections in community-dwelling ... incidence in the consecutive seasons was 7.2% and 11.6%, and influenza virus caused 18.9% and 34.2% of ILI episodes... pathogen were detected in 80% of the ILI events with influenza virus, coronaviruses, rhinoviruses, human metapneumovirus, respiratory syncytial virus, parainfluenza viruses, and Haemophilus influenzae being the most common ...
Vaccines (1)
Human Influenza (16), Infections (4), Respiratory Tract Infections (3), more mentions
The Journal of infectious diseases
... recipients with RSV.Subjects were grouped: upper respiratory tract infection (URTI) without lower respiratory tract infection (LRTI), URTI progressing to LRTI, and LRTI at presentation ... from first RSV diagnosis was lowest in patients presenting with URTI (N = 197; 16... of 16 fewer oxygen-free days than those presenting with URTI (p<0.0001.
Upper Respiratory Tract Infections (1), Respiratory Tract Infections (1), more mentions
The Journal of infectious diseases
AbstractText: Respiratory syncytial virus (RSV) is an important cause of illness in older adults... Keyword: respiratory syncytial virus. Keyword: subunit. Keyword: vaccine.
Vaccines (10)
Human Influenza (1), more mentions
The Journal of infectious diseases
Abstract: Respiratory syncytial virus (RSV) is increasingly recognized as a significant cause of adult respiratory illness. We evaluated routine viral testing and discharge diagnoses for identifying RSV and influenza burden. Polymerase chain reaction results performed in adults during emergency room visits or hospitalizations were reviewed. Peak RSV activity preceded influenza activity by 8 weeks.
Human Influenza (5), more mentions
Importance: Acute lower respiratory tract infection is common and often treated inappropriately in primary care with antibiotics. Corticosteroids are increasingly used but without sufficient evidence. Objective: To assess the effects of oral corticosteroids for acute lower respiratory tract infection in adults without asthma. Design, Setting, and Participants: Multicenter, placebo-controlled, randomized trial (July 2013 to final follow-up October 2014) conducted in 54 family practices in England among 401 adults with acute cough and at least 1 lower respiratory tract symptom not requiring immediate antibiotic treatment and with no history of chronic pulmonary disease or use of asthma medication in the past 5 years. Interventions: Two 20-mg prednisolone tablets (n = 199) or matched placebo (n = 202) once daily for 5 days. Main Outcomes and Measures: The primary outcomes were duration of moderately bad or worse cough (0 to 28 days; minimal clinically important difference, 3.79 days) and mean severity of symptoms on days 2 to 4 (scored from 0 [not affected] to 6 [as bad as it could be]; minimal clinically important difference, 1.66 units). Secondary outcomes were duration and severity of acute lower respiratory tract infection symptoms, duration of abnormal peak flow, antibiotic use, and adverse events. Results: Among 401 randomized patients, 2 withdrew immediately after randomization, and 1 duplicate patient was identified. Among the 398 patients with baseline data (mean age, 47 [SD, 16.0] years; 63% women; 17% smokers; 77% phlegm; 70% shortness of breath; 47% wheezing; 46% chest pain; 42% abnormal peak flow), 334 (84%) provided cough duration and 369 (93%) symptom severity data. Median cough duration was 5 days (interquartile range [IQR], 3-8 days) in the prednisolone group and 5 days (IQR, 3-10 days) in the placebo group (adjusted hazard ratio, 1.11; 95% CI, 0.89-1.39; P = .36 at an α = .05). Mean symptom severity was 1.99 points in the prednisolone group and 2.16 points in the placebo group (adjusted difference, -0.20; 95% CI, -0.40 to 0.00; P = .05 at an α = .001). No significant treatment effects were observed for duration or severity of other acute lower respiratory tract infection symptoms, duration of abnormal peak flow, antibiotic use, or nonserious adverse events. There were no serious adverse events. Conclusions and Relevance: Oral corticosteroids should not be used for acute lower respiratory tract infection symptoms in adults without asthma because they do not reduce symptom duration or severity. Trial Registration: Identifier: ISRCTN57309858.
Infectious Diseases (4)
Respiratory Tract Infections (7), Cough (5), Asthma (3), more mentions
Annals of the rheumatic diseases
OBJECTIVES: To investigate the association between infection or respiratory tract disease and future risk of developing idiopathic inflammatory myopathy (IIM). METHODS: A case-control study was performed using Swedish nationwide registers. Adults with newly diagnosed IIM were identified (2002-2011) from the National Patient Register (NPR) and the Swedish Rheumatology Register (n=957). Controls were matched by age, sex and place of residence (n=9476). Outpatient visits and hospitalisations preceding IIM diagnosis indicating infection or respiratory disease were identified from NPR. Conditional logistic regression models were used to calculate OR and 95% CI. Sensitivity analyses were performed by varying the exposure definition, adjusting for previous healthcare consumption and excluding individuals with connective tissue disease, IIM lung phenotype or IIM-associated cancer. RESULTS: Preceding infections were more common in IIM cases compared with controls (13% vs 9%) and were associated with an increased risk of IIM (OR 1.5, 95% CI 1.2 to 1.9). Gastrointestinal and respiratory tract infections were associated with an increased risk of IIM while cutaneous infections were not.Preceding respiratory tract disease was present in 10% of IIM cases and 4% of controls (OR 2.3, 95% CI 1.8 to 3.0). Both upper and lower respiratory tract diseases were associated with an increased risk of IIM.Variations in exposure and outcome definitions did not greatly affect the results. CONCLUSIONS: Infections and respiratory tract diseases are associated with an increased risk of IIM which suggests that the triggering of the immune system may take place outside the skeletal muscle.
Oncology (1), Muscular and Skeletal Diseases (1)
Infections (8), Respiratory Tract Diseases (6), Respiratory Tract Infections (2), more mentions
Emerging infectious diseases
Age group-specific statistical algorithms may provide insights into the burden on health services and improve early warning in future winters Keyword: England. Keyword: RSV. Keyword: United Kingdom. Keyword: asthma. Keyword: difficulty breathing. Keyword: influenza. Keyword: pneumonia. Keyword: respiratory infections. Keyword: respiratory syncytial virus. Keyword: seasonal. Keyword: severity. Keyword: syndromic surveillance.
Pneumonia (3), Asthma (3), Human Influenza (3), more mentions
Infection control and hospital epidemiology
Abstract: OBJECTIVES To evaluate host characteristics, mode of infection acquisition, and infection control procedures in patients with a positive respiratory syncytial virus (RSV) test result after the introduction of the GenXpert Influenza/RSV polymerase chain reaction (PCR) assay. DESIGN Retrospective cohort study. PATIENTS Adults with a positive PCR test result for RSV who were hospitalized in a tertiary academic medical ...
Infections (8), Human Influenza (2), Community-Acquired Infections (1), more mentions
The Journal of infectious diseases
Nontypeable Haemophilus influenzae (NTHi) persists in the airways in chronic obstructive pulmonary disease (COPD. NTHi expresses four IgA protease variants (A1, A2, B1, B2) with distinct cleavage specificities for human IgA1. Little is known about the different roles of IgA protease variants in NTHi infection.Twenty-six NTHi isolates from a 20-year longitudinal study of COPD were analyzed for ...
Chronic Obstructive Pulmonary Disease (4), Infections (2), more mentions
The Journal of infectious diseases
Vaccine Prevention of Respiratory Syncytial Virus in Older Adults: The Work Continues..
Vaccines (2), more mentions
Critical care medicine
Rhinovirus and human metapneumovirus were more prevalent in severe acute respiratory infection patients (9.6% and 2.6% vs 4.5 and 0.2%; p = 0.006 and p < 0.001... Rhinovirus and human metapneumovirus are more frequently found in severe acute respiratory infection patients. Detection of respiratory viruses is not associated with worse clinically relevant outcomes in the studied cohort of patients.
Respiratory Tract Infections (6), more mentions
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
We evaluated the relationship between initial antibiotic therapy and clinical outcomes in 5005 patients with microbiologically confirmed infections due to Streptococcus pneumoniae. In multivariable analysis, the receipt of "discordant" empiric antibiotic therapy was not associated with 30-day mortality (Hazard Ratio 0.94, 95% CI 0.67-1.32)..
Infectious Diseases (2)
Infections (1), Respiratory Tract Infections (1), more mentions
The Journal of infectious diseases 
CitationSubset: AIM. CitationSubset: IM. DescriptorName: Africa, Western. DescriptorName: Basic Reproduction Number. DescriptorName: Coronavirus Infections. DescriptorName: Data Collection. DescriptorName: Epidemiological Monitoring. DescriptorName: Hemorrhagic Fever, Ebola. DescriptorName: Humans. DescriptorName: Internet. DescriptorName: Republic of Korea. DescriptorName: Spatio-Temporal Analysis. Abstract: The paucity of traditional epidemiological data during epidemic emergencies calls for alternative data streams to characterize the key features of an outbreak, including ...
Ebola Hemorrhagic Fever (6), Coronavirus Infections (1), more mentions
Emerging infectious diseases
... syndrome cases imported into the United States, comprising all passengers and crew on 4 international and domestic flights and 1 bus. Of 655 contacts, 78% were interviewed; 33% had serologic testing. No secondary cases were identified Keyword: Aircraft. Keyword: MERS-CoV. Keyword: Middle East respiratory syndrome coronavirus... Keyword: coronavirus. Keyword: disease notification. Keyword: disease outbreaks. Keyword: respiratory infections. Keyword: travel.
Respiratory Tract Infections (1), Zoonoses (1), more mentions
Abstract: Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes rabies virus, measles virus, and respiratory syncytial virus. Mononegaviruses have non-segmented, single-stranded negative-sense RNA genomes that are encapsidated by nucleoprotein and other viral proteins to form a helical nucleocapsid.
Ebola Hemorrhagic Fever (3), Rabies (1), Measles (1), more mentions
AbstractText: The pathogenesis, viral localization and histopathological features of Middle East Respiratory Syndrome - Coronavirus (MERS-CoV) in human are not sufficiently described... Keyword: Middle East respiratory syndrome coronavirus. Keyword: electron microscopy. Keyword: extra pulmonary. Keyword: histopathology. Keyword: pulmonary. Keyword: renal.
Infectious Diseases (1)
Infections (4), Pneumonia (1), T-Cell Lymphomas (1), more mentions
The Lancet. Respiratory medicine 
The most common adverse events were nasopharyngitis (18 [12%] patients in the treatment group vs 13 [9%] in the placebo group), infections and infestations (25 [17%] vs 21 [14%]), and respiratory, thoracic, and mediastinal disorders (13 [9%] vs 17 [12%]) AbstractText: FeNO measurement is an easy and non-invasive tool ...
Asthma (1), Chronic Obstructive Pulmonary Disease (1), Infections (1), more mentions
Human metapneumovirus (HMPV) is a newly detected pathogen which can cause lower ... In the 59 SOT patients with upper respiratory tract infection (URI), 29 (49%) progressed to lower respiratory tract disease (LRD) after ... pneumonias were detected in nearly half of SOT patients showing URI symptoms with positive HMPV, and low lymphocyte count and high CRP at URI diagnosis were significant factors associated with HMPV pneumonia ...
Pneumonia (5), Infections (3), Respiratory Tract Diseases (2), more mentions
BMJ (Clinical research ed.) 
DescriptorName: Tonsillitis... reference lists of eligible trials, related reviews.Study selection Randomised controlled trials of the addition of corticosteroids to standard clinical care for patients aged 5 or older in emergency department and primary care settings with clinical signs of acute tonsillitis, pharyngitis, or the clinical syndrome of sore throat.
Sore Throat (5), Tonsillitis (2), Pharyngitis (2), more mentions
Rheumatology (Oxford, England)
DescriptorName: Glucocorticoids. DescriptorName: Humans. DescriptorName: Logistic Models. DescriptorName: Longitudinal Studies. DescriptorName: Methotrexate. DescriptorName: Nasopharyngitis. DescriptorName: Patient Reported Outcome Measures. DescriptorName: Quality of Life. DescriptorName: Respiratory Tract Infections. DescriptorName: Severity of Illness Index. DescriptorName: Treatment Outcome. AbstractText: To assess long-term efficacy, safety and tolerability of secukinumab up to 104 weeks in patients with active PsA AbstractText: Patients with PsA (n ...
Muscular and Skeletal Diseases (3), Dermatology (1)
Psoriatic Arthritis (2), Respiratory Tract Infections (1), Diarrhea (1), more mentions
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