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Malaria
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Your search returned 48 results
from the time period: last 90 days.
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The American journal of tropical medicine and hygiene
DescriptorName: Kenya. DescriptorName: Malaria, Falciparum... Abstract: Artemisinin-based combination therapies are recommended as first-line agents for treating uncomplicated Plasmodium falciparum malaria. Ferroquine, a 4-aminoquinolone, is a novel long-acting combination partner for fast-acting drugs like artesunate (AS. We did a small phase 2a, multicenter, open-label, safety-focused dose-ranging randomized study of ferroquine at three African ...
Falciparum Malaria (2), Malaria (1), more mentions
BMJ (Clinical research ed.) 
Drug resistance in malaria, tuberculosis, and HIV in South East Asia: biology, programme, and policy considerations..
Cardiovascular Diseases (2)
Tuberculosis (2), Malaria (2), more mentions
Nature medicine
DescriptorName: Malaria, Falciparum. DescriptorName: Plasmodium falciparum... adoption of artemisinin-based combination therapies (ACTs) in the early 2000s heralded a new era in effectively treating drug-resistant Plasmodium falciparum malaria... how resistance develops, and discuss new strategies for effectively combatting resistance, optimizing treatment and advancing the global campaign to eliminate malaria.
Malaria (2), Falciparum Malaria (1), more mentions
The American journal of tropical medicine and hygiene
... years of its wide-scale use for treatment of uncomplicated Plasmodium falciparum malaria from 2006 to 2014 in Bagamoyo district, Tanzania... Patients with acute uncomplicated P. falciparum malaria were enrolled, treated with standard AL regimen and followed-up ... in Bagamoyo district for the treatment of uncomplicated P. falciparum malaria despite an increase in prevalence of pretreatment Pfmdr1 N86 and ...
Falciparum Malaria (4), Parasitemia (1), more mentions
The Lancet. Global health 
Plasmodium simium: a Brazilian focus of anthropozoonotic vivax malaria?.
Vivax Malaria (2), more mentions
The American journal of tropical medicine and hygiene
The performance of a new Alere™ Malaria Ag P.f Ultra Sensitive rapid diagnostic test (uRDT) was compared with the currently available SD Bioline Malaria Ag P.f RDT in blood specimens from asymptomatic individuals ... well as in pretreatment specimens from study participants from four Plasmodium falciparum-induced blood-stage malaria (IBSM) studies.
Malaria (6), Infections (3), Falciparum Malaria (1), more mentions
Journal of clinical microbiology
... comparing two formats of a commercial LAMP assay (Meridian illumigene® Malaria [M] and Malaria Plus [MP]) versus reference microscopy on archived blood specimens (n=140) obtained from unique returning travelers suspected of having malaria ... reduction in low prevalence non-endemic settings with LAMP-based malaria screening given the excellent negative predictive value achieved with LAMP compared to traditional rapid malaria tests ...
Malaria (8), Communicable Diseases (1), Infections (1), more mentions
The American journal of tropical medicine and hygiene
... purpose of this study is to characterize spatiotemporal heterogeneities in malaria distribution at a provincial level and investigate the association between malaria incidence and climate factors from 2004 to 2014 in China to inform current malaria control efforts ... systems should be applied to monitor resurgence and outbreaks of malaria in mainland China, and quarantine at borders should be reinforced to control the increasingly trend of imported malaria cases ...
Malaria (12), more mentions
The American journal of tropical medicine and hygiene
DescriptorName: Malaria... Abstract: Malaria has been a military problem throughout history capable of causing ... two (1965-1967) soldiers are known to have died with malaria... Lethal epidemics of falciparum malaria occurred in Palestine/Syria in October 1918 and New Guinea ... deployments into Africa including United Nations contingents still show falciparum malaria's lethality despite the availability of effective malaria chemoprophylaxis.
Malaria (6), Falciparum Malaria (2), Infections (2), more mentions
The American journal of tropical medicine and hygiene
DescriptorName: Plasmodium falciparum... step reverse transcriptase real-time PCR (direct RT-PCR) for Plasmodium falciparum malaria parasites that amplifies RNA targets directly from blood... This assay may be useful for monitoring malaria parasite transmission potential in elimination settings, where sensitive diagnostics are needed to evaluate the progress of malaria eradication initiatives ...
Malaria (4), Falciparum Malaria (2), more mentions
The New England journal of medicine
Artemisinin-Resistant Plasmodium falciparum in Africa..
The New England journal of medicine
Artemisinin-Resistant Plasmodium falciparum in Africa..
Scientific reports 
Abstract: Malaria parasites are thought to influence mosquito attraction to human hosts ... report that the human skin odour profile is affected by malaria infection... skin odours from participants that were infected by Controlled Human Malaria Infection with Plasmodium falciparum... To better understand the impact of our findings on Plasmodium transmission, controlled studies are needed in participants with gametocytes and ...
Infections (4), Malaria (3), more mentions
PloS one 
Abstract: Plasmodium vivax is a complex protozoan parasite with over 6,500 genes and stage-specific differential expression. Much of the unique biology of this pathogen remains unknown, including how it modifies and restructures the host reticulocyte. Using a recently published P. vivax reference genome, we report the proteome from two biological replicates of infected Saimiri boliviensis host reticulocytes undergoing ...
Infections (1), more mentions
The American journal of tropical medicine and hygiene
Abstract: Several species of Plasmodium are responsible for causing malaria in humans... can be made using rapid diagnostic tests (RDTs), which detect Plasmodium proteins. Plasmodium falciparum causes the most virulent cases of malaria, and P. falciparum histidine-rich protein 2 (PfHRP2) is a common target of falciparum malaria RDTs ... Here we report a case in which a falciparum malaria patient in Bangladesh tested negative on PfHRP2-based RDTs.
Malaria (3), Falciparum Malaria (2), more mentions
The American journal of tropical medicine and hygiene
Abstract: In this study, we developed a recombinase polymerase amplification (RPA) assay for specific diagnosis of Plasmodium knowlesi... From the specificity experiments, it was demonstrated that all P. knowlesi samples (N = 45) were positive while other Plasmodium spp. N = 42) and negative samples (N = 6) were negative. Therefore, the RPA assay is a highly promising approach with the potential to ...
Blood
Abstract: Plasmodium vivax (Pvivax) is the most prevalent parasite species that causes malaria in humans, and exclusively infects reticulocytes. Reticulocyte infection is facilitated by Pvivax Duffy Binding Protein (DBP), which utilizes DARC (Duffy Antigen Receptor for Chemokines) as an entry point. However, the selective tropism of Pvivax for Transferrin Receptor (CD71)-positive reticulocytes remained unexplained, given the constitutive expression of ...
Infections (2), Malaria (1), more mentions
The American journal of tropical medicine and hygiene
Abstract: Treatment against Plasmodium falciparum malaria includes blood schizonticides to clear asexual parasites responsible for disease. The addition of gametocytocidal drugs can eliminate infectious sexual stages with potential for transmission and the World Health Organization recommends a single dose (SD) of primaquine (PQ) to this end. The efficacy of PQ at 0.75 mg/kg to suppress gametocytemia when administered in ...
Falciparum Malaria (1), more mentions
The American journal of tropical medicine and hygiene
Abstract: Malaria control in West Africa is impeded by the large reservoir of chronic asymptomatic Plasmodium falciparum infections in the human population ... the end of the dry season, the lowest point in malaria transmission over the course of the year... of the P. falciparum reservoir in an area of seasonal malaria transmission in West Africa.
Infections (4), Malaria (4), more mentions
The American journal of tropical medicine and hygiene
Abstract: Malaria transmission-blocking vaccines (TBV) have been evaluated in field trials in Mali, since 2013. However, the assays currently used to measure serum antibody TB activity (TBA) after vaccination are highly variable, in part due to the lack of optimization and standardization for field assays in which mosquitoes feed on gametocytemic blood.
Vaccines (2)
Infections (4), Starvation (2), Malaria (1), more mentions
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