DescriptorName: Hepatitis E. DescriptorName: Hepatitis E virus... AbstractText: To determine the clinical phenotype and outcome in hepatitis E virus-associated neuralgic amyotrophy (HEV-NA) AbstractText: Cases of NA were identified in 11 centers from 7 European countries, with retrospective analysis of demographics, clinical/laboratory findings, and treatment and outcome. Cases of HEV-NA were compared with NA cases without evidence ...
Infectious Diseases (5) Hepatitis E (4), Amyotrophic Neuralgia (2), Hepatitis (1), more mentions
Abstract: Epidemiologic studies examining the association between hepatitis C virus and chronic kidney disease have yielded conflicting findings... of chronic kidney disease were nearly 3-fold higher in hepatitis C virus-infected persons with genotype 2 compared with genotype 1 ... Hepatitis C virus genotype distributions differ in regions around the world.
Kidney Disease (4), Infectious Diseases (4) Chronic Kidney Diseases (4), Hepatitis C (4), more mentions
AbstractText: Direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection has resulted in high rates of disease cure; however, not enough specialists currently are available to provide care AbstractText: To determine the efficacy of HCV treatment independently provided by nurse practitioners (NPs), primary care physicians (PCPs), or specialist ...
Infectious Diseases (2), Immune System Diseases (1) Infections (4), Hepatitis C (2), Cirrhosis (1), more mentions
Little is known about the role of MAIT cells in livers of patients with chronic hepatitis C virus (HCV) infection and their fate after antiviral therapy AbstractText: We collected blood samples from 42 patients with chronic HCV infection who achieved a sustained virologic response after 12 weeks of treatment with ...
Infectious Diseases (3), Immune System Diseases (3) Infections (5), Fibrosis (2), Cirrhosis (1), more mentions
AbstractText: Hepatitis C virus (HCV) infection is associated with diabetes and may worsen glycemic control in patients with diabetes. We aimed to investigate whether eradication of HCV infection with direct-acting antiviral (DAA) agents is associated with improved glycemic control in patients with diabetes AbstractText: We identified 2,435 patients with diabetes who underwent interferon-free and ribavirin-free DAA ...
Endocrine Disorders (7), Immune System Diseases (5), Infectious Diseases (2) Diabetes Mellitus (6), Infections (2), Hepatitis C (2), more mentions
Abstract: Autoimmunehepatitis has a variable occurrence, clinical phenotype, and outcome, and the ... examine the global disparities in the occurrence and outcome of autoimmunehepatitis, suggest bases for these disparities, and encourage investigations that extend ... Disparities in the incidence and prevalence of autoimmunehepatitis in different age groups, genders, ethnicities, and geographical regions suggest ...
Infectious Diseases (7), Immune System Diseases (7) Autoimmune Hepatitis (7), Immune System Diseases (1), Infections (1), more mentions
Advances in autoimmunehepatitis that transform current concepts of pathogenesis and management can be anticipated ... To describe the advances that are likely to become transformative in autoimmunehepatitis, based on the direction of current investigations.Pertinent abstracts were identified ... and cellular interventions constitute the next generation of transformative advances in autoimmunehepatitis.
Infectious Diseases (4), Immune System Diseases (4) Autoimmune Hepatitis (4), more mentions
Abstract: Hepatitis A virus (HAV) infection is an ancient disease and likely to have afflicted mankind since humans first began to live in groups large enough ... hepatic infection it causes in humans, including recently recognized aspects of its molecular virology, evolution, natural history, pathogenesis, epidemiology and prevention Keyword: Hepatitis A virus.
Infectious Diseases (7), Vaccines (1) Hepatitis A (4), Jaundice (3), Infections (2), more mentions
OBJECTIVE: Infections are common and associated with complications and mortality in acute liver failure (ALF). The temporal relationship between ammonia and infection in ALF patients is unclear. We aimed to evaluate the predictors of infection and its relationship with arterial ammonia levels.
MATERIALS AND METHODS: Consecutive ALF patients hospitalized between January 2004 and December 2015, without signs of infection at/within 48 h of admission, were included. Occurrence of infection after 48 h was documented and ammonia levels were estimated for five consecutive days. Multivariate logistic regression analysis was used to assess factors associated with development of infection. Generalized estimating equations (GEE) were used to evaluate five-day time trend of ammonia in patients with and without infection.
RESULTS: Of 540 consecutive patients, 120 were infected at admission/within 48 h and were excluded. Of the rest 420 patients, 144 (34.3%) developed infection after 48 h and 276 (65.7%) remained non-infected. Infected patients had higher mortality than non-infected patients (61.8% vs 40.0%, p < .001). On multivariate analysis, presence of cerebral edema(HR 2.049; 95%CI, 1.30-3.23), ammonia level on day 3 of admission (HR 1.006; 95%CI, 1.003-1.008), and model for end stage liver disease (MELD) score (HR 1.051; 95%CI, 1.026-1.078) were associated with development of infection. GEE showed group difference in serial ammonia values between infected and non-infected patients indicating lack of ammonia decline in infected patients.
CONCLUSIONS: Cerebral edema, elevated ammonia on day 3, and higher MELD score predict the development of infection in ALF. Ammonia persists at high levels in infected patients, and elevated ammonia on day 3 is associated with complications and death.
AbstractText: Hepatitis B vaccine is an effective measure to prevent hepatitis B virus infection. Whether chronic hepatitis C virus (HCV) infection decreases humoral and cell-mediated immunity responses to hepatitis B vaccination is still controversial AbstractText: Patients with chronic HCV infection who were not in treatment and healthy controls, matched ...
Infectious Diseases (17), Vaccines (6) Hepatitis B (12), Chronic Hepatitis C (4), Infections (3), more mentions
... was to examine the risk and determinants of HCC in patients cured with DAA AbstractText: We conducted a retrospective cohort study of hepatitis C virus patients who were treated with DAA in any of the 129 Veterans Health Administration hospitals between January 1, 2015 and December 31 ... Keyword: ViralHepatitis.
Oncology (3), Infectious Diseases (2), Immune System Diseases (1) Cirrhosis (4), Liver Neoplasms (3), Hepatitis (1), more mentions