Abstract: Chronic pulmonaryaspergillosis (CPA) is a severe fungalinfection with a high morbidity and mortality, and is usually seen in immunocompetent patients with respiratory ... a better understanding and to improve CPA patient management and outcome, we established the Chronic PulmonaryAspergillosis Network (CPAnet), a self-organized multinational research collaboration.
... was to investigate the association between PTX3 gene polymorphisms and pulmonaryaspergillosis in chronic obstructive pulmonary disease (COPD) population AbstractText: We included 173 consecutive inpatients with ... 36 cases were finally diagnosed with pulmonaryaspergillosis. Among these, 25 cases were invasivepulmonaryaspergillosis (IPA) and 11 cases were chronic pulmonaryaspergillosis (CPA ...
Abstract: Opportunistic infections caused by Pneumocystis jirovecii, Cryptococcus neoformans, and ubiquitous airborne filamentous fungi have been recently reported in patients with hematological cancers historically considered at low risk for invasivefungalinfections (IFIs), after receipt of the Bruton tyrosine kinase inhibitor ibrutinib... Keyword: invasivefungalinfections. Keyword: opportunistic infections. Keyword: small molecule tyrosine kinase inhibitors.
Immune System Diseases (1) Infections (3), Opportunistic Infections (2), Autoimmune Diseases (1), more mentions
Abstract: Some fungalinfections may lead to devastating destruction of face, sometimes followed by fatal consequences. Conidiobolus coronatus is a rare, but serious emerging fungal pathogen of humans, causing Conidiobolomycosis, commonly infecting nasal mucosa and with potential to extend to involve vital structures such as brain and eyes. Treatment of this infection is extremely difficult and can cause significant disfiguring ...
Together these findings revealed an important role for caspase-8 in the innate immune response of host cells to P. brasiliensis infection, demonstrating a connected network between non-canonical and canonical inflammasomes to coordinate IL-1β production during fungal challenge Keyword: IL-1β production. Keyword: P. brasiliensis. Keyword: caspase-8. Keyword: non-canonical inflamassome pathway. Keyword: paracoccidioidomycosis.
However, inborn errors in STAT4, which controls IL-12 responses, have not yet been reported AbstractText: To determine the underlying genetic defect in a family with a history of paracoccidioidomycosis (PCM) disease AbstractText: Genetic analysis was performed by whole-exome sequencing and sanger sequencing... Keyword: Paracoccidioidomycosis disease. Keyword: Primary Immunodeficiency.
DescriptorName: Treatment Outcome. Abstract: Pneumococcal mycotic aneurysms are rare and associated with significant mortality and morbidity... We present the case of a man in his mid 70s with multiple thoracoabdominal mycotic aneurysms. Surgery was performed to a threatening saccular aortic arch aneurysm. Samples were sent for microbiological analysis and all were culture negative.
... candidate and was treated with rtPA who experienced a fatal subarachnoid hemorrhage due to a ruptured mycotic aneurysm (MA) AbstractText: A 51-year-old man presented to the Emergency Department with acute neurological ... CT angiography to rule out MA prior to treating presumed acute ischemic stroke with rtPA Keyword: mycotic aneurysm.
Folliculotropic mycosis fungoides (F-MF) is a variant of mycosis fungoides characterized by preferential infiltration of the follicular epithelium by atypical T lymphocytes, with or without follicular mucinosis or infiltration of ... It is the most common subtype of mycosis fungoides (MF) in adults, with 4% frequency according to WHO classification.
The impact of ID in mycosis fungoides (MF) is unknown AbstractText: Our goal was to evaluate the impact of ID in MF AbstractText: We conducted a case-control study of 17 patients with MF and ID versus age-, stage-, and race-matched controls as a subset of ... Keyword: mycosis fungoides.
Abstract: Unilesional follicular mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma characterized by selective involvement of the hair follicles by neoplastic T lymphocytes presenting initially as a solitary lesion occupying less than 5% of the body surface; there are 22 previous reported cases. We describe 6 patients with this rare variant of MF, all males (age ...
Men's Health (1) Mycosis Fungoides (2), Alopecia Areata (1), Follicular Mucinosis (1), more mentions
UV- based (PUVA and Narrow Band UVB) phototherapy is broadly and commonly used in the treatment of Cutaneous T-cell Lymphomas (CTCL), yet unfortunately the evidence for the efficacy of these treatments is based only on cases series or prospective but non-randomized studies. Therefore, no internationally approved guidelines exists and no standardization of schedules have been proposed. Recently, Consensus guidelines have been published by the United States Cutaneous Lymphoma Consortium. The aim of this paper is to review the biologic and clinical evidences on PUVA and NB UVB in CTCL, and to critically evaluate acceptability and feasibility of these guidelines in the real-life setting from the perspective of the Cutaneous Lymphoma Task Force of the Italian Lymphoma Foundation (Fondazione Italiana Linfomi, FIL). This article is protected by copyright. All rights reserved.