CitationSubset: IM. DescriptorName: Adult. DescriptorName: Aortic Valve. DescriptorName: Echocardiography. DescriptorName: Endocarditis, Bacterial... Abstract: Prosthetic valve endocarditis is a very grave and often terminal disease... Herein, we describe the implantation under direct visualization of a self-expandable transcatheter heart valve in a prohibitive surgical risk patient with homograft aortic valve endocarditis.
Endocarditis (4), Streptococcal Infections (1), Prosthesis-Related Infections (1), more mentions
... are associated with improved outcomes for patients with S aureus bacteremia, including appropriate antibiotic prescribing, use of echocardiography to identify endocarditis, and consultation with infectious diseases (ID) specialists ... care processes has increased in routine care for S aureus bacteremia or whether use of these processes has led to large ... evidence-based care processes in routine care for S aureus bacteremia with mortality AbstractText: This retrospective observational cohort study examined all ...
... To assess the relation between invasive dental procedures and infective endocarditis associated with oral streptococci among people with prosthetic heart valves ... 2008 and July 2014.Main outcome measures Oral streptococcal infective endocarditis was identified using primary discharge diagnosis codes... were performed to estimate the rate of oral streptococcal infective endocarditis during the three month period after invasive dental procedures compared ...
However, a comprehensive comparison between these pathogens involved in bacteremia episodes has yet to be reported.In this retrospective cohort study, adults with community-onset monomicrobial bacteremia caused by E coli or K pneumoniae were recruited in ... more patients with fatal comorbidities (McCabe classification), critical illness (Pitt bacteremia score ≥ 4) at bacteremia onset, and initial syndrome (e.g., severe sepsis and septic ...
Bacteremia (10), Abscesses (3), Klebsiella Infections (1), more mentions
... of this study was to determine discrepancies in 3D LV endocardial tracings and suggest tracing guidance AbstractText: Forty-five 3D LV ... The 3D meshes were compared with one another, and the endocardial areas of discrepancies were identified... and -4.2 ± 4.1%, respectively) AbstractText: Comparing 3D LV tracings, the endocardial areas that are the most difficult to delineate were identified.
This study aimed to define endocardial UV cutoff values using computed tomography-derived fat information and ... Eighty-six percent of abnormal epicardial electrograms had corresponding endocardial sites with BV <1.50 mV, and the remaining could be identified by corresponding low endocardial UV <3.7 mV AbstractText: For identification of epicardial right ventricular scar, an endocardial UV cutoff value of 3.9 mV is more accurate than ...
BACKGROUND: The significance of fractionated electrograms (EGMs) is object of debate, with multiple mechanisms described.
OBJECTIVE: Using Rhythmia, a high-density mapping system, we sought to investigate the relationship between specific electrophysiological phenomena and EGM characteristics at those sites.
METHODS: Twenty-five consecutive patients underwent high-density atrial mapping during atrial tachycardias. Bipolar EGMs were recorded with a 64-electrode basket catheter. The following atrial phenomena were identified: slow conduction (SC) areas, lines of block, wavefront collisions, pivot sites (PS), and gaps. EGMs collected at these predefined areas were analyzed in terms of amplitude, duration, and morphology.
RESULTS: Twenty-five atrial maps with 195 sites of interest (1755 EGMs) were object of our analysis. Thirty-five percent were sites of SC: fractionation had low amplitude (0.16 ± 0.07 mV) and long duration (87.8 ± 10.7 ms); wavefront collisions were seen in 38% of sites with EGMs shorter in duration (46.5 ± 4.5 ms) and higher in voltage (0.58 ± 0.13 mV); 17% were lines of block, never responsible for fractionation (0.13 ± 0.05 mV; 122.4 ms ± 24.8 ms); 9% were PS with a high degree of fractionation (0.55 ± 0.15 mV; 85.8 ± 7.9 ms). Two gaps were identified (1%) with a low degree of fractionation.
CONCLUSION: Specific EGM characteristics in atrial tachycardia can be reproducibly linked to electrophysiological mechanisms. High-voltage and short-duration EGMs are associated with collision sites and PS that are unlikely to form critical sites for ablation; long-duration, low-voltage EGMs are associated with SC. However, not all SC regions will lie within the critical circuit and identification by only EGM characteristics cannot guide ablation.
... were identified as independent correlates of atrial fibrillation recurrence AbstractText: Our report demonstrated that the majority of patients after epicardial ablation, using bipolar radiofrequency instruments, required endocardial catheter ablation to complete the linear ablation lesions and a significant proportion of patients required spot-ablations to complete electric pulmonary vein isolation.
The optimal duration of antibiotic therapy for Gram-negative bacteraemia (GNB), a common community and hospital-associated infection, remains unknown and unstudied via randomised ... Immunosuppressed patients and those with GNB due to complicated infections (endocarditis, osteomyelitis, etc) and/or non-fermenting bacilli (Acinetobacter spp, Burkholderia spp, Pseudomonas spp) Brucella ... Keyword: Bacteraemia.
Abstract: This study investigated the clinical characteristics and outcomes of bacteraemia due to Burkholderia cepacia complex (BCC) species among 54 patients ... Bacteraemic pneumonia (n=23, 42.6%) and catheter-related bacteraemia (n=21, 38.9%) were the most common types of infection... Bacteraemia caused by BCC species other than B. cenocepacia and B ...
Cystic Fibrosis (1), Pneumonia (1), Infections (1), more mentions
... of cefazolin versus nafcillin for methicillin-susceptible Staphylococcus aureus (MSSA) bacteraemia AbstractText: A prospective observational cohort study including all S. aureus bacteraemia was conducted at 10 hospitals ... Patients (≥15 years) with MSSA bacteraemia who received cefazolin or nafcillin as definitive antibiotics were included... recommended as an adequate and better-tolerated treatment for MSSA bacteraemia in the absence of CIE Keyword: Bacteraemia.
Infectious Diseases (4) Sepsis (2), Infections (1), more mentions
Mandatory surveillance of E. coli bacteraemia was introduced in 2011 with the aim of improving the ... applying time-of-onset categorization to cases of E. coli bacteraemia in England AbstractText: Data for all cases of E. coli bacteraemia reported to Public Health England between April 2012 and March ... 16 (P <0.001) AbstractText: Approximately one-fifth of E. coli bacteraemia cases reported via mandatory surveillance were identified as hospital-onset.
The quantitative impact of severity of illness on pharmacodynamic thresholds is poorly defined. We used a robust cefepime outcomes cohort and previously identified pharmacodynamic breakpoints of 68% [pharmacokinetic (PK) model 1] and 74% (PK model 2) to probe interactions and relationships with modified Acute Physiology and Chronic Health Evaluation (mAPACHE) II scores. When the time that serum concentration remains above the minimum inhibitory concentration during the dosing interval (fT>MIC) was optimised, mortality was improved between mAPACHE II scores of 9-23 and 9-22 in models 1 and 2, respectively. No significant interactions were identified. These results suggest that mAPACHE II scores of 9-22 may fall within a 'Goldilocks' window in which hospital survival is improved among patients achieving goal fT>MIC thresholds.
Sensitivity (85.7% vs. 42.9%) and negative predictive value (98.4% vs. 87.0%) tended to be higher for SF than for BC AbstractText: The results of SF and BC show that bacteraemia and fungaemia are present in CF patients during FPE and may affect antibiotic therapy. SF can help rule out catheter-related bloodstream infections.