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Cutaneous Lymphoma
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Your search returned 38 results
from the time period: last 90 days.
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... presence and degree of peripheral blood involvement in patients with cutaneous T-cell lymphoma (CTCL) portend a worse clinical outcome... Peripheral blood CTCL malignant cells were isolated from 25 patients and exposed ex ... alone and in combination, and comparisons were made to 4 CTCL cell lines (Hut78, Sez4, HH, MyLa.
Cutaneous T-Cell Lymphoma (2), B-Cell Lymphoma (1), Non-Hodgkin Lymphoma (1), more mentions
Cutaneous T-cell lymphomas (CTCLs) are extremely symptomatic and still incurable, and more effective and ... was to evaluate the anti-tumor activity of ONC201 on CTCL cells... ONC201 on the cell growth and apoptosis were evaluated in CTCL cell lines (n=8) and primary CD4(+) malignant T cells isolated from CTCL patients (n=5 ...
Neoplasms (2), Cutaneous T-Cell Lymphoma (2), more mentions
Leukemia & lymphoma
Abstract: Cutaneous T-cell lymphomas (CTCL) are a group of non-Hodgkin lymphomas that typically present in the skin but can progress to ... histone deacetylase inhibitor approved for the treatment of patients with CTCL who have had ≥1 prior systemic therapy... suggest that romidepsin is safe and effective in patients with CTCL who received prior systemic chemotherapy Keyword: Cutaneous T-cell lymphoma.
Cutaneous T-Cell Lymphoma (3), Non-Hodgkin Lymphoma (1), more mentions
The British journal of dermatology
propose alternate dosing regimens of brentuximab vedotin (BV) for CD30+ cutaneous T-cell lymphomas (CTCLs) such as mycosis fungoides (MF) and primary cutaneous anaplastic large cell lymphoma (pcALCL).(1) They emphasize that lower doses or less frequent dosing schedules for CTCL may be equally effective while limiting adverse events ... The authors indicate that CTCLs may require less aggressive therapy than systemic lymphomas such as systemic ALCL (sALCL) or Hodgkin lymphoma (HL ...
Cutaneous T-Cell Lymphoma (2), Mycosis Fungoides (1), Hodgkin Disease (1), more mentions
Cancer treatment reviews
Abstract: Patients with relapsed or refractory cutaneous T-cell lymphoma (CTCL) display a dismal prognosis and their therapy represents an unmet ... and ongoing clinical trials in patients with relapsed and refractory CTCL... to expand the therapeutics options available in the management of CTCL Keyword: ARGX-110... Keyword: cutaneous T-cell lymphoma.
Cutaneous T-Cell Lymphoma (3), more mentions
Acta dermato-venereologica
... R) has been shown to assess illness perception reproducibly in primary cutaneous T-cell lymphomas (CTCL... of the relationships between illness perception, illness behaviour, and HRQOL in CTCL and cutaneous B-cell lymphomas (CBCL... IPQ-R assessment in CTCL and CBCL might be a useful instrument to improve individual disease ...
B-Cell Lymphoma (1), Lymphoma (1), Cutaneous T-Cell Lymphoma (1), more mentions
Journal of the European Academy of Dermatology and Venereology : JEADV
... phototherapy is broadly and commonly used in the treatment of Cutaneous T-cell Lymphomas (CTCL), yet unfortunately the evidence for the efficacy of these treatments ... biologic and clinical evidences on PUVA and NB UVB in CTCL, and to critically evaluate acceptability and feasibility of these guidelines ... in the real-life setting from the perspective of the Cutaneous Lymphoma Task Force of the Italian Lymphoma Foundation (Fondazione Italiana Linfomi, FIL ...
Lymphoma (4), Mycosis Fungoides (1), Cutaneous T-Cell Lymphoma (1), more mentions
American journal of hematology
Abstract: The transcription factor GATA-3, highly expressed in many cutaneous T-cell lymphoma (CTCL) and peripheral T-cell lymphomas (PTCL), confers resistance to chemotherapy in a cell-autonomous manner ... examined in patient-derived cell lines and primary T-cell lymphoma specimens ex vivo treated with the oral proteasome inhibitor ixazomib... II study with this agent in patients with relapsed/refractory CTCL/PTCL was conducted.
T-Cell Lymphomas (3), Cutaneous T-Cell Lymphoma (1), more mentions
The British journal of dermatology
... vedotin (BV) is an anti-CD30 antibody-drug conjugate that is approved for refractory Hodgkin lymphoma and systemic anaplastic large-cell lymphoma. In the ALCANZA trial, the proportion of CD30+ cutaneous T-cell lymphoma (CTCL) patients achieving an objective response lasting at least 4 months was 56.3% with BV versus ...
Peripheral Nervous System Diseases (1), Hodgkin Disease (1), Anaplastic Large-Cell Lymphoma (1), more mentions
Expanding and expounding the genomic map of CTCL..
Abstract: Although inhibitors of epigenetic regulators have been effective in the treatment of cutaneous T cell lymphoma (CTCL) and other hematopoietic malignancies, they have been less effective in solid tumors, including ovarian ... CAOV3 cells, HDAC inhibition induces the CXCL8 expression in HeLa cells, but not in CTCL Hut-78 cells.
Oncology (4)
Ovarian Neoplasms (4), Lymphoma (1), Neoplasms (1), more mentions
Journal of the European Academy of Dermatology and Venereology : JEADV
AbstractText: Mycosis fungoides (MF) is the major subtype of cutaneous T-cell lymphomas (CTCL... subsisted between FKBP51 and TRAF2 IHC expression scores AbstractText: We hypothesize a role for FKBP51 as a prognostic marker for MF and suggest an involvement of this immunophilin in deregulated NF-κB pathway of this CTCL.
Mycosis Fungoides (2), Necrosis (1), Cutaneous T-Cell Lymphoma (1), more mentions
Journal of dermatological science
Differential expression of CCR4 in primary cutaneous gamma/delta (γ⁄δ) T cell lymphomas and mycosis fungoides: Significance for diagnosis and therapy..
Lymphoma (2), Mycosis Fungoides (2), more mentions
The American Journal of dermatopathology
... lymphocytes with cleaved nuclei, which raised the possibility of primary cutaneous CD8 aggressive epidermotropic cytotoxic T-cell lymphoma... Other diagnoses, such as primary cutaneous acral CD8 T-cell lymphoma-a provisional entity, were also considered but did not capture all the features of this patient's lymphoma ... We propose to classify this case as a primary cutaneous CD8 T-cell lymphoma, an indolent and locally aggressive form.
T-Cell Lymphomas (5), Lymphoma (2), Paronychia (1), more mentions
International journal of radiation oncology, biology, physics
To determine the optimal radiation dose for treatment of primary cutaneous anaplastic large cell lymphoma (C-ALCL) with solitary or localized, multifocal or recurrent skin lesions.In this multicenter study, patients with ... been treated with radiation therapy (RT) between 1984 and 2016 were retrieved from the Dutch registry of cutaneous lymphomas.
Lymphoma (2), Primary Cutaneous Anaplastic Large Cell Lymphoma (2), more mentions
International journal of dermatology
Primary cutaneous diffuse large B-cell lymphoma presenting as a solitary subcutaneous nodule with TP53 and FBXW7 mutations..
Diffuse Large B-Cell Lymphoma (2), more mentions
The American Journal of dermatopathology
... represents the transformation of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma into an aggressive large B-cell lymphoma... Primary cutaneous CD4-positive small/medium T-cell lymphoma (CD4 PCSM-TCL) characteristically presents with a dense dermal infiltrate ... characteristics, the differential diagnosis includes not only other forms of cutaneous T-cell lymphomas but also B-cell lymphomas and reactive lymphoid infiltrates ...
Oncology (1)
Chronic B-Cell Lymphocytic Leukemia (3), B-Cell Lymphoma (2), T-Cell Lymphomas (2), more mentions
The American Journal of dermatopathology
Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT) represents approximately 20% of cutaneous B lymphomas with an intermediate prognosis. Spontaneous regression is uncommon; there are only 2 published cases. An 83-year-old woman presented 2 orange erythematous nodules on the back of her right leg with an elastic consistency, infiltrated, painful to the touch, and of ...
Diffuse Large B-Cell Lymphoma (2), Neoplasms (1), Lymphoma (1), more mentions
The British journal of dermatology
We thank the authors Lewis, Kim, and Duvic, for their reaction to our article. The increasingly personalised medicine should also take into account individual tumour entities and their inter-individual pathways. Therefore, we can only welcome and sustain the comments. As described in our article, it is possible, in some patients, to reduce the dose and interval frequency of Brentuximab Vedotin (BV), while continuing to have good efficacy. This article is protected by copyright. All rights reserved.
Cutaneous T-Cell Lymphoma (1), more mentions
The British journal of dermatology
Image Gallery: Secondary cutaneous involvement of the ear with systemic small lymphocytic lymphoma: a rare manifestation..
Chronic B-Cell Lymphocytic Leukemia (2), more mentions
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