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Cutaneous Lymphoma
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Your search returned 33 results
from the time period: last 90 days.
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Molecular cancer therapeutics
Abstract: Cutaneous T-cell lymphoma (CTCL) is a heterogeneous neoplasm and patients with relapsed/refractory disease ... plays a critical role in protection from oxidative stress in CTCL cells... a pharmacologic inhibitor, GO-203, was associated with apoptosis in CTCL... need for combinatorial strategies that could exploit the vulnerability of CTCL cells to oxidative signals.
Oncology (1)
Cutaneous T-Cell Lymphoma (2), Neoplasms (1), more mentions
International journal of dermatology
Although cutaneous T-cell lymphoma (CTCL) has been reported in patients with CLL, the incidence and ... Among patients identified, we evaluated the incidence of CTCL AbstractText: Among 31,286 patients with CLL, the incidence of CTCL was not significantly higher in men than women: 104.2 (95 ... The incidence of CTCL among males with CLL (standardized incidence ratio [SIR], 3.0 [95 ...
Oncology (9)
Chronic B-Cell Lymphocytic Leukemia (3), Cutaneous T-Cell Lymphoma (2), Non-Hodgkin Lymphoma (2), more mentions
Oncotarget
Abstract: Cutaneous T-cell lymphomas (CTCLs) are extremely symptomatic and still incurable, and more effective and ... was to evaluate the anti-tumor activity of ONC201 on CTCL cells... ONC201 on the cell growth and apoptosis were evaluated in CTCL cell lines (n=8) and primary CD4+ malignant T cells isolated from CTCL patients (n=5 ...
Oncology (2)
Neoplasms (3), Cutaneous T-Cell Lymphoma (2), more mentions
Leukemia & lymphoma
Abstract: Cutaneous T-cell lymphomas (CTCL) are a group of non-Hodgkin lymphomas that typically present in the skin but can progress to ... histone deacetylase inhibitor approved for the treatment of patients with CTCL who have had ≥1 prior systemic therapy... suggest that romidepsin is safe and effective in patients with CTCL who received prior systemic chemotherapy Keyword: Cutaneous T-cell lymphoma.
Cutaneous T-Cell Lymphoma (3), Non-Hodgkin Lymphoma (1), more mentions
The British journal of dermatology
propose alternate dosing regimens of brentuximab vedotin (BV) for CD30+ cutaneous T-cell lymphomas (CTCLs) such as mycosis fungoides (MF) and primary cutaneous anaplastic large cell lymphoma (pcALCL).(1) They emphasize that lower doses or less frequent dosing schedules for CTCL may be equally effective while limiting adverse events ... The authors indicate that CTCLs may require less aggressive therapy than systemic lymphomas such as systemic ALCL (sALCL) or Hodgkin lymphoma (HL ...
Cutaneous T-Cell Lymphoma (2), Mycosis Fungoides (1), Hodgkin Disease (1), more mentions
Blood
Abstract: As with many immunopathologically driven diseases, the malignant T cells of cutaneous T-cell lymphomas (CTCLs), such as Sézary syndrome, display aberrant cytokine secretion patterns that contribute to pathology and disease progression ... release of cytokines is complicated by the changing cytokine milieu that drives the phenotypic changes of CTCLs.
Cutaneous T-Cell Lymphoma (1), more mentions
American journal of hematology
Abstract: The transcription factor GATA-3, highly expressed in many cutaneous and peripheral T-cell lymphomas, confers resistance to chemotherapy in a cell-autonomous manner ... examined in patient-derived cell lines and primary T-cell lymphoma specimens ex vivo treated with the oral proteasome inhibitor ixazomib... II study with this agent in patients with relapsed/refractory CTCL/PTCL was conducted... Keyword: cutaneous T-cell lymphoma.
T-Cell Lymphomas (4), Cutaneous T-Cell Lymphoma (1), more mentions
International journal of dermatology
AbstractText: The utility of brentuximab vedotin (BV) in CD30(+) systemic lymphomas is established, however evidence for treating primary cutaneous lymphoma remains limited ... BV in treating CD30(+) transformed mycosis fungoides (MF) and primary cutaneous anaplastic large cell lymphoma (PC-ALCL) AbstractText: A literature review was conducted, and we ... Preliminary results indicate that BV is effective for CD30(+) CTCL, however additional studies with larger sample sizes are necessary.
Lymphoma (2), Mycosis Fungoides (1), Cutaneous T-Cell Lymphoma (1), more mentions
The British journal of dermatology
Some prior studies could demonstrate good efficacy in cutaneous lymphomas... Background of this work is the fact that cutaneous lymphoma has a different pathophysiology, and a dynamic other than systemic lymphoma ... seems to be a powerful treatment option in refractory CD30+ CTCL, and there is a trend that dose reductions, as well ...
Lymphoma (4), Cutaneous T-Cell Lymphoma (1), more mentions
Journal of cutaneous pathology
Abstract: Primary cutaneous aggressive cytotoxic epidermotropic CD8+ T-cell lymphoma is an extremely rare, rapidly progressing, cutaneous lymphoma, with frequent systemic involvement and poor prognosis, that still represents ... interface dermatitis-like pattern, revealing the deceptive features that early cutaneous infiltrates of this aggressive lymphoma may have. A high suspicion for aggressive CTCL and a low threshold for repeat biopsies should be maintained ...
Dermatology (2)
Erythema (3), T-Cell Lymphomas (3), Dermatitis (2), more mentions
Blood
Abstract: Cutaneous T cell lymphoma (CTCL) is an incurable non-Hodgkin lymphoma of the skin-homing T cell ... To clarify the genomic basis of CTCL, we performed genomic analysis of 220 CTCLs... putative driver genes, including 17 genes not previously implicated in CTCL... Collectively, our analysis provides novel insights into CTCL pathogenesis and elucidates the landscape of potentially targetable gene mutations.
Oncology (1)
Neoplasms (2), Lymphoma (1), Non-Hodgkin Lymphoma (1), more mentions
Cancer cell
Abstract: In this issue of Cancer Cell, Qu et al. describe the chromatin accessibility profiles of cutaneous T cell lymphoma, with dynamic assessments of response and resistance to histone deacetylase inhibitor therapy. Their "personal regulome" analysis framework reveals chromatin features that may be predictive of clinical response to epigenetic therapy.
Oncology (1)
Neoplasms (1), Lymphoma (1), more mentions
Journal of the American Academy of Dermatology
... trended toward improved outcomes (P = .07) AbstractText: Retrospective analysis AbstractText: African American patients with MF demonstrated poorer survival than white patients after accounting for disease characteristics, socioeconomic factors, and types of treatment, warranting further investigation into the underlying biology of MF and prescribed treatment modalities Keyword: cutaneous T-cell lymphoma.
Oncology (2)
Mycosis Fungoides (4), Neoplasms (2), Cutaneous T-Cell Lymphoma (1), more mentions
The British journal of dermatology
Image Gallery: Secondary cutaneous involvement of the ear with systemic small lymphocytic lymphoma: a rare manifestation..
Chronic B-Cell Lymphocytic Leukemia (2), more mentions
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Unusual presentation of primary cutaneous follicle centre B-cell Lymphoma (PC-FCL) of the nose..
B-Cell Lymphoma (2), more mentions
International journal of colorectal disease
A rare case of peristomal cutaneous B cell lymphoma..
Lymphoma (2), more mentions
The Journal of investigative dermatology
Spindle-cell variant of primary cutaneous follicle center B-cell lymphomas are germinal center B-cell lymphomas by gene expression profiling using formalin-fixed paraffin embedded specimen..
B-Cell Lymphoma (4), more mentions
American journal of hematology
AbstractText: Cutaneous T-cell lymphomas are a heterogenous group of T-cell lymphoproliferative disorders involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS) AbstractText: The diagnosis of MF or SS requires the integration of clinical and histopathologic data AbstractText: TNMB (tumor ...
Oncology (1)
Cutaneous T-Cell Lymphoma (2), Mycosis Fungoides (1), Lymphoproliferative Disorders (1), more mentions
Journal of the European Academy of Dermatology and Venereology : JEADV
AbstractText: Primary cutaneous B-cell lymphomas (PCBCL) are frequently misdiagnosed and a biopsy is needed to attain the correct diagnosis ... 17 cases for a dermoscopic differential diagnosis AbstractText: Of 172 biopsy-proven PCBCL lesions, cutaneous lymphoma was suspected by the clinician in 16.3%; the leading diagnosis was basal cell carcinoma ...
Oncology (1)
Basal Cell Carcinoma (2), B-Cell Lymphoma (2), Amelanotic Melanoma (1), more mentions
The Journal of investigative dermatology
Abstract: Multiple genomic mutations, especially those involving the NF-κB pathway, have been characterized in primary cutaneous large B-cell lymphoma, leg type. However, its genomic profiling remains limited given its rarity. In a recent study, Mareschal et al. performed next-generation sequencing and whole-exome sequencing, identifying new driver genes while also confirming the role of myeloid differentiation primary ...
B-Cell Lymphoma (2), more mentions
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