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Pancreatic Disease
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Your search returned 28 results
from the time period: last 90 days.
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BMJ (Clinical research ed.)
Type 3c diabetes associated with pancreatic disease is often misdiagnosed, finds study..
Endocrine Disorders (2)
Pancreatic Diseases (2), Diabetes Mellitus (2), more mentions
Gastrointestinal endoscopy
... occurred on July 26, 2017 in 4 sessions: (1) benign pancreatic diseases, (2) high-risk pancreatic diseases, (3) diagnostic and therapeutics, and (4) new technologies ... themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders, the technique of sampling pancreatic lesions, and the performance of ...
Endocrine Disorders (2), Kidney Disease (2)
Pancreatic Diseases (4), Kidney Diseases (2), Diabetes Mellitus (2), more mentions
Pancreas
... occurred on July 26, 2017 in 4 sessions: (1) benign pancreatic diseases, (2) high-risk pancreatic diseases, (3) diagnostic and therapeutics, and (4) new technologies ... themes included the need for large multicenter consortia of various pancreatic diseases to facilitate meaningful research of these entities; to standardize EUS features of different pancreatic disorders, the technique of sampling pancreatic lesions, and the performance of ...
Endocrine Disorders (2), Kidney Disease (2)
Pancreatic Diseases (4), Kidney Diseases (2), Diabetes Mellitus (2), more mentions
International journal of cancer
... ductal adenocarcinoma (PDAC) is a very aggressive tumor with a five-year survival of less than 6. Chronic pancreatitis (CP), an inflammatory process in of the pancreas, is a strong risk factor for PDAC... Our study suggests that CP and PDAC probably do not share genetic susceptibility, at least in terms of high frequency variants Keyword: Chronic pancreatitis. Keyword: association.
Oncology (1)
Chronic Pancreatitis (3), Adenocarcinoma (2), Pancreatic Neoplasms (1), more mentions
European journal of cancer (Oxford, England : 1990)
... MTA (HR, 0.29; 95% CI, 0.11-0.76; p = 0.008) AbstractText: Within the MOSCATO-01 trial, patients with aBTCs had the highest rate of orientation to matched MTAs and derived a clear clinical benefit. A broader evaluation of these findings may improve future treatments strategies for aBTCs AbstractText: NCT01566019 Keyword: Biliary tract carcinoma. Keyword: Cholangiocarcinoma. Keyword: Molecular screening. Keyword: Precision medicine.
Oncology (1)
Cholangiocarcinoma (1), Carcinoma (1), Biliary Tract Neoplasms (1), more mentions
European journal of cancer (Oxford, England : 1990)
Our study includes a small number of patients and does not enable to draw definitive conclusions; however, it provides useful insights into potential transcripts that may deserve further investigation in larger cohorts of patients AbstractText: Nanostring data have been submitted to GEO repository: GSE90698 and GSE90699 Keyword: Adjuvant. Keyword: CD80. Keyword: CTLA4. Keyword: Cholangiocarcinoma. Keyword: Treg.
Cholangiocarcinoma (1), more mentions
Cancer
... patients who have BTC with positive regional lymph nodes, including the impact of surgery and adjuvant therapy (AT), is unclear AbstractText: This was a retrospective cohort study of patients who had T1-T3N1M0 gallbladder cancer (GBC) and intrahepatic cholangiocarcinoma (IHC) in the National Cancer Database (2004-2012... Keyword: intrahepatic cholangiocarcinoma.
Oncology (7)
Neoplasms (3), Gallbladder Neoplasms (2), Cholangiocarcinoma (2), more mentions
Scandinavian journal of gastroenterology
BACKGROUND: The use of computed tomography (CT) in acute pancreatitis (AP) continues to increase in parallel with the increasing use of diagnostic imaging in clinical medicine. AIM: To determine the factors associated with obtaining >1 CT scan in acute interstitial pancreatitis (AIP). METHODS: Demographic and clinical data of all adult patients admitted between 1/2010 and 1/2015 with AP (AP) were evaluated. Only patients with a CT severity index (CTSI) ≤ 3 on a CT obtained within 48 h of presentation were included. RESULTS: A total of 229 patients were included, of whom 206 (90%) had a single CT and 23 (10%) had >1 CT during the first week of hospitalization. Patients undergoing >1 CT had significantly higher rates of acute fluid collection (AFC), persistent SIRS, opioid use ≥4 days, and persistent organ failure compared to those undergoing 1 CT (p < .05 for all). On multivariable analysis, only persistent SIRS (OR = 3.6, 95% CI 1.4-9.6, p = .01) and an AFC on initial CT (OR = 3.5, 95% CI 1.4-9, p = .009) were independently associated with obtaining >1 CT. CONCLUSION: An AFC on initial CT and persistent SIRS are associated with increased CT imaging in AIP patients. However, these additional CT scans did not change clinical management.
Pancreatitis (3), more mentions
Scandinavian journal of gastroenterology
Patients with primary sclerosing cholangitis (PSC) have increased risk of cholangiocarcinoma (CCA. We evaluated pre-transplant work-up in PSC patients, to search for the most effective strategy for the detection of biliary dysplasia or early CCA.Two hundred and twenty five consecutive PSC patients undergoing liver transplantation (LTx) in Sweden between 1999 and 2013 were studied.
Sclerosing Cholangitis (2), Cholangiocarcinoma (1), more mentions
Digestion
... of AiP among patients with pancreatitis presenting to our tertiary referral center in Mannheim, Germany; and to estimate the incidence of AiP in the Southwest of Germany.We performed a retrospective cross-sectional analysis and determined the prevalence of AiP in patients with acute pancreatitis (AP) or chronic pancreatitis (CP.
Immune System Diseases (3)
Pancreatitis (9), Alcoholic Pancreatitis (3), Chronic Pancreatitis (1), more mentions
Gut
The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation..
Chronic Pancreatitis (2), more mentions
Annals of oncology : official journal of the European Society for Medical Oncology
Patient 1 had lung adenocarcinoma and patient 2 cholangiocarcinoma... Cholangiocarcinoma is not a disease type in which NRG1 fusions had previously been described. Integrative genome analysis was used to assess the potential functional significance of the detected genomic events including the gene fusions, prioritizing therapeutic strategies targeting the HER-family of growth factor receptors.
Oncology (2)
Cholangiocarcinoma (2), Lung Neoplasms (1), Neoplasms (1), more mentions
Gut
Improving future studies in chronic pancreatitis: a paradigm shift in our understanding?.
Chronic Pancreatitis (2), more mentions
Journal of surgical oncology
Herein, we investigated survival differences and recurrence patterns after adjuvant chemoradiotherapy by perioperative CA19-9 change in surgically resected extrahepatic cholangiocarcinoma.Patients were divided into those with preoperative normal CA19-9 (Group 1, n = 52), those with high preoperative and normalized postoperative CA19-9 (Group 2, n = 80), and those ...
Oncology (1)
Cholangiocarcinoma (2), more mentions
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
In some HCC cases we sequenced HBV PreS-S gene, C/E1 and NS5B fragment of HCV, and analyzed their genotypes.Among histologically confirmed 2172 PLC cases, 1823 (83.9%) were hepatocellular carcinoma (HCC), 238 (11.0%) were intrahepatic cholangiocarcinoma. Among HCC cases, HBV infection alone, indicated by HBsAg(-)/(+)&anti-HBc(+), was found in 1567 (86.0%) cases, of them 18.2% (331/1823 ...
Oncology (6), Infectious Diseases (3)
Infections (3), Liver Neoplasms (3), Neoplasms (3), more mentions
BMJ open
INTRODUCTION: Acute pancreatitis (AP) is an inflammatory disease with no specific treatment. Mitochondrial injury followed by ATP depletion in both acinar and ductal cells is a recently discovered early event in its pathogenesis. Importantly, preclinical research has shown that intracellular ATP delivery restores the physiological function of the cells and protects from cell injury, suggesting that restoration of energy levels in the pancreas is therapeutically beneficial. Despite several high quality experimental observations in this area, no randomised trials have been conducted to date to address the requirements for energy intake in the early phase of AP. METHODS/DESIGN: This is a randomised controlled two-arm double-blind multicentre trial. Patients with AP will be randomly assigned to groups A (30 kcal/kg/day energy administration starting within 24 hours of hospital admission) or B (low energy administration during the first 72 hours of hospital admission). Energy will be delivered by nasoenteric tube feeding with additional intravenous glucose supplementation or total parenteral nutrition if necessary. A combination of multiorgan failure for more than 48 hours and mortality is defined as the primary endpoint, whereas several secondary endpoints such as length of hospitalisation or pain will be determined to elucidate more detailed differences between the groups. The general feasibility, safety and quality checks required for high quality evidence will be adhered to. ETHICS AND DISSEMINATION: The study has been approved by the relevant organisation, the Scientific and Research Ethics Committee of the Hungarian Medical Research Council (55961-2/2016/EKU). This study will provide evidence as to whether early high energy nutritional support is beneficial in the clinical management of AP. The results of this trial will be published in an open access way and disseminated among medical doctors. TRIAL REGISTRATION: The trial has been registered at the ISRCTN (ISRTCN 63827758).
Pancreatitis (2), more mentions
Journal of hepatology
No Abstract Available
Hepatocellular Carcinoma (2), more mentions
Gastrointestinal endoscopy
No Abstract Available
Cholangitis (2), Pancreatitis (2), more mentions
Journal of gastrointestinal cancer
AbstractText: The potential of biomarkers in detecting early cholangiocarcinoma (CCA) is facilitated by examining CCA-associated proteins from primary studies... Keyword: Cholangiocarcinoma. Keyword: MUC5AC. Keyword: Meta-analysis.
Oncology (1)
Cholangiocarcinoma (3), Neoplasms (1), more mentions
Journal of hepatology
... for the risk of false positive diagnosis in case of cholangiocarcinoma... Of 1006 nodules, HCC were 820 (81%), cholangiocarcinoma 40 (4%), regenerative nodules (±dysplastic) 116 (11... predictive of HCC, with no risk of misdiagnosis for pure cholangiocarcinoma... Over 75% of cholangiocarcinomas were LR-M. The LR-3 category included 203 lesions ...
Cholangiocarcinoma (6), Hepatocellular Carcinoma (4), Cirrhosis (3), more mentions
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