... Patient reported outcomes (PROs) are important treatment endpoints in inflammatory boweldiseases (IBD... evaluated the gastrointestinal (GI) PRO Measurement Information System (PROMIS) in IBD subjects AbstractText: Crohn's and Colitis Foundation of America's Partners is an Internet-based cohort of IBD subjects ... surveys, including demographics, disease characteristics, PROMIS domains, disease activity (short Crohn's disease activity index or simple clinical colitis activity index) and quality of life (QoL) indices ...
Immune System Diseases (2), Urology (1) Colitis (2), Inflammatory Bowel Diseases (2), Ulcerative Colitis (1), more mentions
... FMT in patients with C. difficile infection with underlying inflammatory bowel disease (IBD), including the risk of IBD flare... also emerging evidence supporting the role of FMT to treat IBD including promising randomized trials in ulcerative colitis... FMT (1) to treat C. difficile infection in patients with IBD, (2) to treat underlying IBD, and (3) outline ongoing clinical trials and the future of ...
... 1 month, 3 months, and 1 year in patients with IBD AbstractText: We performed a retrospective cohort study using the electronic ... December 2010 with a primary discharge diagnosis of either ulcerative colitis or Crohn's disease... index admissions with a primary discharge diagnosis of either ulcerative colitis or Crohn's disease were eligible for inclusion in the study.
Immune System Diseases (2), Endocrine Disorders (1) Ulcerative Colitis (2), Inflammatory Bowel Diseases (2), Heart Failure (1), more mentions
AbstractText: Intestinal barrier defects are common in patients with inflammatory bowel disease (IBD... performed an in-depth analysis of epithelial barrier genes in IBD AbstractText: A set of 128 intestinal barrier genes was selected... based on selected barrier gene variants that were associated with Crohn's disease (CD) or ulcerative colitis (UC) in our study.
Immune System Diseases (1) Inflammatory Bowel Diseases (2), Ulcerative Colitis (1), more mentions
... the efficacy of an autoimmune protocol diet in patients with Crohn's disease and ulcerative colitis AbstractText: We enrolled adults with active IBD (Harvey-Bradshaw index ≥ 5 or partial Mayo score ≥3 and ... to 1.2 (SD 2.0) and 1.0 (SD 2.0) for ulcerative colitis, and mean Harvey-Bradshaw index significantly improved from 7 (SD ...
Immune System Diseases (6) Ulcerative Colitis (2), Inflammatory Bowel Diseases (2), more mentions
... is controversy over how to best manage patients with inflammatory bowel disease (IBD) and flat low-grade dysplasia (fLGD) in the colon ... tissues with fLGD from 37 patients undergoing surveillance colonoscopy for IBD, from 1990 to 2015 at the University of California at ... to a morphological impression or suspicion of flat HGD Keyword: IBD.
Abstract: A major challenge in inflammatory bowel disease (IBD) is the integration of diverse IBD data sets to construct predictive models of IBD ... We present a predictive model of the immune component of IBD that informs causal relationships among loci previously linked to IBD through genome-wide association studies (GWAS) using functional and regulatory ...
AbstractText: Clinical use of biosimilar infliximab (CT-P13) in inflammatory boweldiseases (IBDs) is based on extrapolation of indication from clinical studies performed in rheumatological diseases ... of 62 patients were included in the final analysis (32 Crohn's disease, 30 ulcerative colitis (UC) or IBD-unclassified... .05) occurred in the entire study group or in the Crohn's disease (CD) subgroup (5.75 and 6.5 mg/l, p = .68.
Immune System Diseases (3) Ulcerative Colitis (3), Inflammatory Bowel Diseases (2), more mentions
AbstractText: The impact of diagnostic delay in inflammatory bowel disease, including Crohn's disease (CD) and ulcerative colitis (UC), on disease course remains uncertain ... diagnosis, disease phenotype, and complications in 177 patients with inflammatory bowel disease (110 CD and 67 UC) diagnosed at our institution ... Video Abstract, Supplemental Digital Content 1, http://links.lww.com/IBD/B646.
Immune System Diseases (1) Pathologic Constriction (3), Inflammatory Bowel Diseases (3), Abscesses (1), more mentions
In contrast to adult-onset inflammatory bowel disease (IBD), where many genetic loci have been shown to be involved in complex disease etiology, early-onset IBD (eoIBD) and associated syndromes can sometimes present as monogenic conditions ... in these patients often differ from those in adult-onset IBD... patients.We selected 28 genes of interest associated with monogenic IBD and performed targeted panel sequencing in 71 patients diagnosed with ...
... 11β-HSD enzyme system in the colon of patients with IBD.By using quantitative real-time PCR, we investigated the transcription ... levels of 11β-HSD1 and 2 in colonic tissue from IBD patients and healthy controls undergoing a colonoscopy for disease assessment... Dysregulation in this pathway could have a potential role in IBD pathogenesis and may account for exogenous glucocorticoid resistance in IBD.
... or its pre-cursor lesion, dysplasia, in patients with inflammatory bowel disease (IBD).To assess the effectiveness of cancer surveillance programs for diagnosis of IBD-associated colorectal cancer and in reducing the mortality rate from colorectal cancer in patients with IBD.We searched MEDLINE, EMBASE, CENTRAL and clinical clinicaltrials.gov from ...
Oncology (27), Immune System Diseases (1) Neoplasms (5), Colorectal Neoplasms (4), Inflammatory Bowel Diseases (2), more mentions
... corticosteroids and biologic therapies versus oral systemic corticosteroids for ulcerative colitis (UC).The PubMed database was searched for clinical and observational ... budesonide," "infliximab," "adalimumab," "golimumab," and "vedolizumab" in combination with "ulcerative colitis" or "inflammatory bowel disease."A total of 582 studies were identified from PubMed ... see Video Abstract, Supplemental Digital Content, http://links.lww.com/IBD/B653.
Immune System Diseases (1) Ulcerative Colitis (3), Inflammatory Bowel Diseases (1), Infections (1), more mentions
... Breastfeeding is a modifiable factor that may influence development of inflammatory boweldiseases... to examine the association between breastfeeding in infancy and risk of Crohn's disease (CD) and ulcerative colitis (UC) AbstractText: A systematic search of Medline/PubMed and Embase was ... Breastfeeding in infancy protects against the development of CD and ulcerative colitis.
Immune System Diseases (2) Ulcerative Colitis (3), Inflammatory Bowel Diseases (1), more mentions
... 25% of leucopenia cases.To identify the clinical risk factors for thiopurine-induced leucopenia in patients without a common TPMT variant, and explore if these patients are at increased risk for infections.Post hoc analysis of the Thiopurine response Optimisation by Pharmacogenetic testing in Inflammatory bowel disease Clinics (TOPIC) trial.
AbstractText: To examine the association between chronic immune-mediated diseases (rheumatoid arthritis, systemic lupus erythematosus or the following chronic immune-mediated inflammatory diagnoses groups: inflammatory boweldiseases, inflammatory polyarthropathies, systemic connective tissue disorders and spondylopathies) and the 6-year coronary artery disease, stroke ... The population attributable fractions for all three disorders were 13.4%, 15.7% and 10.7%, respectively AbstractText: Systemic connective tissue disorders and rheumatoid arthritis conferred the highest cardiovascular risk and population impact, followed by inflammatory boweldiseases Keyword: Arthritis ...
Cardiovascular Diseases (6), Immune System Diseases (4), Muscular and Skeletal Diseases (1) Cardiovascular Diseases (5), Inflammatory Bowel Diseases (4), Rheumatoid Arthritis (3), more mentions