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... performed based on the method of detection for progression of hepaticfibrosis and quality of studies AbstractText: We included 10 studies (1 ... For progression of hepaticfibrosis, pooled HR (95% confidence interval) was 0.49 (0.39-0.62... by residual confounding AbstractText: Statins may retard the progression of hepaticfibrosis, may prevent hepatic decompensation in cirrhosis, and may reduce all ...
Abstract: We investigated the possible link between livercirrhosis and gallstone risk in chronic hepatitis C (CHC) patients in China.To analyze the association between livercirrhosis and gallstone development, we compared outcomes of 133 Chinese CHC ... group of 431 CHC patients without gallstones.We found that livercirrhosis was more prevalent in gallstone patients (40.6%) than in the ...
Infectious Diseases (5), Endocrine Disorders (1) Gallstones (12), Liver Cirrhosis (11), Hepatitis C (3), more mentions
... samples AbstractText: Metabolomic analysis of urine spectra using (1)H-NMR spectroscopy can recognize a specific individual profile in all patients with chronic hepatitis C. However, this method cannot yet differentiate with sufficient accuracy, patients with advanced fibrosis from patients with milder disease Keyword: Chronic hepatitis C. Keyword: Hepaticfibrosis.
Infectious Diseases (4) Fibrosis (7), Chronic Hepatitis C (4), Cirrhosis (2), more mentions
Abstract: Hepaticfibrosis is potentially reversible; however early diagnosis is necessary for treatment ... ongoing with multiple other techniques for the noninvasive diagnosis of hepaticfibrosis, including MRI with diffusion-weighted imaging, hepatobiliary contrast enhancement, and ... Efforts to advance the noninvasive imaging assessment of hepaticfibrosis will facilitate earlier diagnosis and improve patient monitoring with the ...
BACKGROUND & AIMS: Liver fibrosis is the single most important prognostic factor in patients with non-alcoholic fatty liver disease (NAFLD). The predictive value of the AST to Platelet Ratio Index (APRI) score, originally developed for fibrosis assessment in hepatitis C virus (HCV) patients, is much less known in the context of NAFLD patients.
METHODS: We retrospectively compared the performance of APRI and fibrosis 4 calculator (FIB-4) scores in NAFLD patients with documented liver biopsies, to their performance in chronic HCV patients.
RESULTS: 153 patients with biopsy-proven NAFLD and 297 patients with biopsy-proven chronic HCV infection were included. The APRI score was a good predictor for advanced fibrosis in NAFLD patients (area under the ROC curve 0.8307) although it was modestly inferior as compared to the well-validated FIB-4 score (area under the ROC curve 0.8959). The predictive value of APRI score in NALFD patients was inferior as compared to its predictive value in HCV patients (area under the ROC curve of 0.8307 versus 0.9965). In contrast to FIB-4, APRI score was not a good discriminator between intermediate stages of fibrosis in NAFLD patients.
CONCLUSIONS: APRI and Fib-4 scores are reasonable tools to allocate NAFLD patients with advanced fibrosis. FIB-4 may better discriminate between intermediate fibrosis stages.
... diagnostic accuracy of a novel serological panel (BioFibroScore®) to predict hepaticfibrosis in patients with chronic hepatitis C virus (HCV) infection is ... The diagnostic accuracy of hepaticfibrosis was assessed both for BioFibroScore® and FibroScan®, taking METAVIR fibrosis ... and MMP-9 was negatively associated with the severity of hepaticfibrosis.
Infectious Diseases (3) Fibrosis (10), Chronic Hepatitis C (2), Infections (1), more mentions
AbstractText: To determine if hepatic venous pressure gradient (HVPG) correlates with advanced hepaticfibrosis, as a complement to transjugular (transvenous) core needle liver biopsy AbstractText: After institutional review board approval ... CI 0.26-0.50) for diagnosis of stage 4 fibrosis AbstractText: HVPG correlates with stage 4 (advanced) hepaticfibrosis Keyword: Biopsy.
Infectious Diseases (3), Immune System Diseases (1) Fibrosis (11), Cirrhosis (1), Alcoholic Steatohepatitis (1), more mentions
DescriptorName: Biomarkers, Tumor. DescriptorName: Carcinoma, Hepatocellular. DescriptorName: China. DescriptorName: Female. DescriptorName: Hepatitis B. DescriptorName: Hepatitis B virus. DescriptorName: Humans. DescriptorName: LiverCirrhosis. DescriptorName: Liver Neoplasms. DescriptorName: Male. DescriptorName: Middle Aged. DescriptorName: Protein Precursors. DescriptorName: Prothrombin. DescriptorName: alpha-Fetoproteins. Abstract: Alpha-fetoprotein is an effective biomarker as an aid in hepatocellular carcinoma detection in many countries.
Infectious Diseases (5) Hepatocellular Carcinoma (13), Hepatitis B (5), Neoplasms (2), more mentions
DescriptorName: Creatinine. DescriptorName: Cystatin C. DescriptorName: Diagnostic Errors. DescriptorName: Female. DescriptorName: Glomerular Filtration Rate. DescriptorName: Humans. DescriptorName: LiverCirrhosis. DescriptorName: Male. DescriptorName: Middle Aged. DescriptorName: ROC Curve. DescriptorName: Renal Insufficiency. DescriptorName: Young Adult. Abstract: Hepatic cirrhosis is often accompanied by functional kidney impairment, which may be reversed if early treatment is promptly administered.
AbstractText: Livercirrhosis induces marked metabolic disorders, protein-energy malnutrition, and sarcopenia... systemic glucose metabolism, skeletal muscle, and prognosis of patients with livercirrhosis AbstractText: Japanese patients with livercirrhosis (n = 21) were enrolled into a longitudinal study in which ... which may contribute to improving the survival of patients with livercirrhosis Keyword: Branched-chain amino acids.
Liver Cirrhosis (6), Sarcopenia (3), Hypoalbuminemia (3), more mentions
However, little is known about whether the severity of livercirrhosis has an effect on the incidence of HCC... was utilized to estimate the association of the complications of livercirrhosis with the risk of HCC... In conclusion, complicated livercirrhosis is associated with a higher risk of HCC in Taiwan ...
Cirrhosis (10), Liver Cirrhosis (4), Hepatocellular Carcinoma (2), more mentions
... on mortality rates may not reveal the true burden of livercirrhosis, and (2) diverse use of diagnostic coding may produce misleading ... Office for National Statistics death registry was interrogated to investigate livercirrhosis mortality trends in England and Wales from 1968 to 2011 ... AbstractText: Standardised mortality trends according to three different definitions of livercirrhosis based on the specificity of diagnostic codes were calculated: 1 ...
Liver Cirrhosis (8), Cirrhosis (4), Liver Diseases (3), more mentions