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Pituitary Diseases and Tumors
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Your search returned 34 results
from the time period: last 90 days.
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Medicine
DescriptorName: ACTH-Secreting Pituitary Adenoma... report a case of 37-year-old male who had cryptococcal meningitis after transnasal transsphenoidal pituitary microsurgery of a relapsing ACTH-secreting pituitary adenoma AbstractText: Standard therapy for Cryptococcus neoformans (fluconazole [400 mg per day] and flucytosine) was administered and followed by maintenance dose AbstractText: The ...
Infectious Diseases (7)
Cryptococcal Meningitis (4), ACTH-Secreting Pituitary Adenoma (3), Infections (3), more mentions
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Abstract: Growth hormone-secreting pituitary adenoma accounts for about 20% of the third most common intracranial neoplasm-pituitary adenomas-which makes up 15% of all intracranial tumors ... protein expression was markedly higher in invasive growth hormone-secreting pituitary adenoma than non-invasive growth hormone-secreting pituitary adenoma... serve as a useful biomarker to assess growth hormone-secreting pituitary adenoma invasion and prognosis or a potential therapeutic target for growth hormone-secreting pituitary adenoma treatment Keyword: Epidermal growth factor–like domain multiple 7 protein ...
Oncology (3)
Growth Hormone-Secreting Pituitary Adenoma (12), Neoplasms (5), Intracranial Neoplasms (1), more mentions
Endocrine-related cancer
Abstract: Pituitary adenomas (PA) represent the largest group of intracranial neoplasms and yet the molecular mechanisms driving this disease remain largely unknown... Keyword: pituitary adenoma. Keyword: tumour suppressor.
Pituitary Adenoma (3), Intracranial Neoplasms (1), Retinoblastoma (1), more mentions
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Abstract: Human pituitary adenoma is one of the most common intracranial tumors with an ... factors of pituitary or hypothalamic origin and proliferation of human pituitary adenoma cells... factor gene on the proliferation, migration, and invasion of human pituitary adenoma cells. Human pituitary adenoma tissues were collected to obtain human pituitary adenoma cells.
Oncology (1)
Pituitary Adenoma (10), Pituitary Neoplasms (4), Neoplasm Invasiveness (1), more mentions
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
... were 11/50 and H-Scores 22.75 ± 11.83 in invasive pituitary adenomas and 26/53 and 66.3 ± 21.7 in non-invasive pituitary adenomas (χ(2) = 8.182, p = 0.004 ... significant difference (p < 0.01) in 4 CpG sites between invasive pituitary adenoma group and non-invasive pituitary adenoma group; furthermore, the relieved methylation levels of H3K4/H3K9 and ...
Pituitary Adenoma (10), Pituitary Neoplasms (1), Neoplasms (1), more mentions
Pituitary
... Cochrane database and Science Research, using the key-words: "double pituitary adenomas", "multiple pituitary adenomas" and only papers where multiple or truly separate double pituitary adenomas were identified pre-surgically by MRI and/or confirmed by ... from 1975 to 2016 and found 17 cases with two pituitary adenomas and 1 with three pituitary adenomas.
Pituitary Adenoma (9), Adenoma (5), Acromegaly (2), more mentions
World neurosurgery
AbstractText: Surgical treatment of giant pituitary adenomas is sometimes challenging... Keyword: Pituitary adenoma. Keyword: Transsphenoidal surgery.
Neoplasms (9), Adenoma (3), Pituitary Adenoma (3), more mentions
The American journal of surgical pathology
... and immunohistochemistry between a clinically nonfunctioning pituitary neuroendocrine tumor (NET)/pituitary adenoma and a primary or secondary NET of nonpituitary origin in ... None of the pituitary tumors expressed serotonin, suggesting that serotonin immunoreactive sellar tumors represent primary ... Normal expression of ATRX and DAXX in pituitary tumors suggests that ATRX and DAXX do not play a role ...
Neoplasms (3), Pituitary Adenoma (2), Neuroendocrine Tumors (2), more mentions
Endocrine
... 18 healthy controls and 29 subjects with a history of pituitary disease during standard corticotrophin-releasing hormone test AbstractText: Patients with previous pituitary disease were subdivided in a group passing the test (P1, n ... copeptin response was higher in controls than in subjects with pituitary disease (area under the curve, p = 0.04 for P1 + P2) with ...
Endocrine Disorders (1)
Pituitary Diseases (4), Diabetes Insipidus (1), more mentions
The Journal of clinical endocrinology and metabolism
... are at high risk for several types of cancer, but pituitary tumors have not previously been reported.A 51-year old man ... carcinoma presented with severe Cushing's disease and a locally aggressive pituitary tumor... a nationwide study in LS.A diagnosis consistent with a pituitary tumor was sought for in the Swedish National Patient Registry.
Oncology (2)
Pituitary Neoplasms (7), Neoplasms (6), Carcinoma (2), more mentions
Pituitary
... the goal of generate uniform criteria among centers dealing with pituitary tumors and to enhance patient care, the Pituitary Society decided to generate criteria for developing Pituitary Tumors Centers of Excellence (PTCOE) AbstractText: To develop that task, a ... tool to guide improvements of care delivery to patients with pituitary disorders.
Pituitary Neoplasms (3), Acromegaly (1), more mentions
Neurology
Optical coherence tomography angiography in pituitary tumor..
Pituitary Neoplasms (2), more mentions
Endocrine
Increased miR-338-3p expression correlates with invasiveness of GH-producing pituitary adenomas..
Pituitary Adenoma (2), more mentions
Clinical endocrinology
Thyrotropin (TSH)-secreting pituitary adenomas (TSH-oma) are rare and account for about 0.5-3% of all pituitary adenomas. Patients with TSH-oma present themselves mostly with central hyperthyroidism expressing increased circulating levels of TSH, free T4 and T3.(1) TSH-omas are usually benign tumours and express somatostatin receptors subtypes 2 and 5.
Pituitary Adenoma (3), Hyperthyroidism (1), more mentions
Medicine
AbstractText: Case reports concerning the value of dopamine agonists in the treatment of patients with thyrotropin-secreting pituitary adenoma (TSHoma) are limited. Herein, we present a rare case of octreotide-insensitive TSHoma responding to bromocriptine therapy AbstractText: A 45-year-old Chinese man was admitted to Peking Union Medical College Hospital with marked clinical manifestations of hyperthyroidism AbstractText: Thyroid function ...
Pituitary Adenoma (2), Neoplasms (2), Hyperthyroidism (1), more mentions
Journal of neurosurgery
Keyword: EEA = endoscopic endonasal approach. Keyword: GH = growth hormone. Keyword: IGF-I = insulin-like growth factor–I. Keyword: PRISMA = Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Keyword: PRL = prolactin. Keyword: acromegaly. Keyword: endonasal. Keyword: endoscopic. Keyword: growth hormone. Keyword: pituitary surgery. Keyword: pituitary tumor. Keyword: reoperation. Keyword: transsphenoidal.
Endocrine Disorders (2)
Acromegaly (7), Neoplasms (5), Diabetes Insipidus (2), more mentions
Journal of neurosurgery 
Abstract: OBJECTIVE Pituitary adenomas account for approximately 10% of intracranial tumors and have an ... Resection is the primary treatment for pituitary adenomas, and the transsphenoidal approach remains the most common. The greatest challenge with pituitary adenomas is that 20% of patients develop tumor recurrence... Pituitary adenomas are known to overexpress folate receptor alpha (FRα), and it ...
Neoplasms (9), Pituitary Adenoma (8), Adenoma (7), more mentions
World neurosurgery
AbstractText: The type of pituitary adenoma with a manifestation that includes cavernous sinus syndrome is rare ... study investigated the pathogenesis, imaging characteristics, and prognostic factors of pituitary adenoma with cavernous sinus syndrome AbstractText: We conducted a retrospective analysis of the characteristics of pituitary adenoma patients with cavernous sinus syndrome who received surgical treatment ...
Pituitary Adenoma (7), Pituitary Apoplexy (2), Cranial Nerve Diseases (1), more mentions
Acta neurochirurgica
AbstractText: Radiographic detection of calcification in pituitary adenoma is relatively rare, and the clinical characteristics of pituitary adenoma with calcification remain unclear ... Herein, the clinical characteristics of pituitary adenoma with radiological calcification were investigated AbstractText: A total of 160 patients who underwent surgical resection of pituitary adenomas between February 2004 and December 2016 were reviewed ...
Pituitary Adenoma (13), Neoplasms (3), Prolactinoma (2), more mentions
Pituitary
BACKGROUND: Studies comparing primary medical treatment of acromegaly with surgery are often non-randomized, and not stratified by illness severity. We prospectively compared primary medical therapy with pituitary surgery in patients with acromegaly. All patients had macroadenomas, at least one random human growth hormone (GH) level ≥12.5 ng/mL, elevated IGF-I levels and failure to suppress GH to <1 ng/mL during an oral glucose tolerance test (oGTT). METHODS: Forty-one patients from seven centers were randomized to primary treatment with octreotide LAR, 30 mg every 4 weeks × 3 months (ARM A, N = 15), or pituitary surgery (ARM B, N = 26) using a 1:2 randomization design. Patients cured by surgery (defined as nadir GH during oGTT <1 ng/mL and normal IGF-I) received no subsequent treatment. Those not cured surgically were then treated with octreotide LAR (SubArm B1) for 3 months. RESULTS: Only one of the 15 patients in ARM A (6.7%) had normalization of both GH and IGF-I. In contrast, 13/26 patients had normalization of both GH and IGF-I after surgery alone (50%). Of the remaining 13 patients who did not normalize with surgery alone, treatment with octreotide LAR resulted in a normal nadir GH and normal serum IGF-I in 7 (53.9%). In total, 20/26 in ARM B (76.9%) experienced normalization of defined biochemical acromegaly parameters. CONCLUSIONS: Pituitary surgery alone was more effective than primary medical treatment (p = 0.006), and the combination of surgery followed by medical therapy was even more effective (p < 0.0001). Subjects treated with medical therapy after surgical debulking had a significant improvement in response rate compared to matched subjects treated with primary medical therapy.
Acromegaly (5), Pituitary Adenoma (1), more mentions
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