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Pancreatitis and Pancreatic Endocrine Tumors
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Your search returned 58 results
from the time period: last 90 days.
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BMJ (Clinical research ed.) 
DescriptorName: Pancreatic Neoplasms... 537 lung cancer, 11 488 colorectal cancer, 4369 ovarian cancer, 1896 pancreatic cancer, and 1627 neuroblastoma) and 84 418 controls.Exposures Four single nucleotide ... were the risk of incident colorectal, breast, prostate, ovarian, lung, and pancreatic cancer and neuroblastoma, which was evaluated with an inverse variance weighted average ...
Oncology (21)
Neoplasms (8), Colorectal Neoplasms (4), Prostatic Neoplasms (4), more mentions
The British journal of surgery 
DescriptorName: Middle Aged. DescriptorName: Operative Time. DescriptorName: Pancreatic Ducts. DescriptorName: Pancreatic Neoplasms. DescriptorName: Pancreaticoduodenectomy. DescriptorName: Postoperative Complications. AbstractText: Laparoscopic resection as an alternative to open pancreatoduodenectomy may yield short-term benefits, but has not been investigated in a randomized trial. The aim of this study was to compare laparoscopic and open pancreatoduodenectomy for short-term outcomes in a randomized trial ...
Pancreatic Neoplasms (1), Pancreatic Fistula (1), more mentions
Mayo Clinic proceedings
DescriptorName: Pancreas. DescriptorName: Pancreatic Cyst. DescriptorName: Pancreatic Neoplasms. Abstract: Our treatment approach for either symptomatic or incidentally found pancreatic cysts continues to improve. The true incidence of pancreatic cysts is not known, and pancreatic cystic neoplasms, especially intraductal papillary mucinous neoplasms, are currently most commonly diagnosed and resected. This is a result of increasing awareness, widespread availability of imaging, and ...
Pancreatic Cysts (5), Neoplasms (3), Pancreatic Neoplasms (1), more mentions
Journal of the National Cancer Institute
DescriptorName: Pancreatic Neoplasms... variables, may facilitate the identification of the metabolic drivers of pancreatic cancer AbstractText: We identified genetic instruments for obesity, body shape, dyslipidemia ... a likelihood-based MR approach within a series of 7110 pancreatic cancer patients and 7264 control subjects using genome-wide data from the Pancreatic Cancer Cohort Consortium (PanScan) and the Pancreatic Cancer Case-Control Consortium (PanC4 ...
Oncology (10), Endocrine Disorders (8), Anti-Obesity and Weight Loss (6)
Pancreatic Neoplasms (11), Diabetes Mellitus, Type 2 (5), Obesity (4), more mentions
Annals of surgery
DescriptorName: Humans. DescriptorName: Male. DescriptorName: Margins of Excision. DescriptorName: Middle Aged. DescriptorName: Neoplasm Staging. DescriptorName: Pancreatic Neoplasms. DescriptorName: Pancreaticoduodenectomy. DescriptorName: Prognosis. DescriptorName: Prospective Studies. DescriptorName: Survival Analysis. DescriptorName: Treatment Outcome. AbstractText: The aim of the study was to assess the relevance of resection margin status for survival after resection of pancreatic-head ductal adenocarcinoma AbstractText: The definition and prognostic value ...
Oncology (1)
Neoplasms (5), Adenocarcinoma (2), Pancreatic Neoplasms (1), more mentions
Diabetes care
Eighty-five and 1,589 subjects who developed pancreatic cancer were registered among the incretin and NIAD new users, respectively, which represented an aHR of pancreatic cancer of 2.14 (95% CI 1.71-2.67) among those prescribed an ... The risk of pancreatic cancer among patients subsequently prescribed insulin was 6.89 (6.05-7.85) AbstractText ...
Oncology (11), Endocrine Disorders (3)
Pancreatic Neoplasms (11), Diabetes Mellitus (3), more mentions
Gastroenterology
... discover germline variants in coding regions that affect risk for pancreatic cancer, combining data from 5 studies... analyzed exome and genome sequencing data from 437 patients with pancreatic cancer (cases) and 1922 individuals not known to have cancer (controls ... as the most common high-penetrant genetic factor associated with pancreatic cancer and we also identified candidate pancreatic cancer genes.
Oncology (11)
Pancreatic Neoplasms (8), Neoplasms (3), more mentions
Gastrointestinal endoscopy
... and is considered to be an emergent therapeutic target for pancreatic cancer... oligonucleotide that specifically represses CHST15, for use in patients with pancreatic cancer AbstractText: Six patients with unresectable pancreatic cancer, treated at Tokyo Metropolitan Geriatric Hospital, were used in this ... the other 4 patients AbstractText: EUS-FNI of STNM01 in pancreatic cancer is safe and feasible.
Oncology (5)
Neoplasms (7), Pancreatic Neoplasms (5), Necrosis (1), more mentions
Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose: Survival for pancreatic ductal adenocarcinoma (PDAC) patients is extremely poor and improved therapies are urgently needed. Tumor-infiltrating lymphocyte (TIL) adoptive cell therapy (ACT) has shown great promise in other tumor types, such as metastatic melanoma where overall response rates of 50% have been seen. Given this success and the evidence showing that T-cell presence positively correlates with overall survival in PDAC, we sought to enrich for CD8(+) TILs capable of autologous tumor recognition. In addition, we explored the phenotype and T-cell receptor repertoire of the CD8(+) TILs in the tumor microenvironment.Experimental Design: We used an agonistic 4-1BB mAb during the initial tumor fragment culture to provide 4-1BB costimulation and assessed changes in TIL growth, phenotype, repertoire, and antitumor function.Results: Increased CD8(+) TIL growth from PDAC tumors was achieved with the aid of an agonistic 4-1BB mAb. Expanded TILs were characterized by an activated but not terminally differentiated phenotype. Moreover, 4-1BB stimulation expanded a more clonal and distinct CD8(+) TIL repertoire than IL2 alone. TILs from both culture conditions displayed MHC class I-restricted recognition of autologous tumor targets.Conclusions: Costimulation with an anti-4-1BB mAb increases the feasibility of TIL therapy by producing greater numbers of these tumor-reactive T cells. These results suggest that TIL ACT for PDAC is a potential treatment avenue worth further investigation for a patient population in dire need of improved therapy. Clin Cancer Res; 23(23); 1-13. ©2017 AACR.
Oncology (3)
Neoplasms (11), Pancreatic Neoplasms (1), Melanoma (1), more mentions
Proceedings of the National Academy of Sciences of the United States of America 
Only one of the 182 plasma samples from the control cohort was positive for any of the DNA or protein biomarkers (99.5% specificity. This combinatorial approach may prove useful for the earlier detection of many cancer types Keyword: circulating tumor DNA. Keyword: early cancer detection. Keyword: liquid biopsy. Keyword: pancreatic cancer. Keyword: protein biomarkers.
Oncology (6)
Neoplasms (8), Adenocarcinoma (2), Pancreatic Neoplasms (1), more mentions
The Journal of clinical endocrinology and metabolism
DescriptorName: Longitudinal Studies. DescriptorName: Male. DescriptorName: Middle Aged. DescriptorName: Multiple Endocrine Neoplasia Type 1. DescriptorName: Neuroendocrine Tumors. DescriptorName: Pancreatic Neoplasms. DescriptorName: Prognosis. DescriptorName: Retrospective Studies. DescriptorName: Time Factors. DescriptorName: Tumor Burden. DescriptorName: Young Adult. AbstractText: Pancreatic neuroendocrine tumors (pNETs) are highly prevalent in patients with multiple endocrine neoplasia type 1 (MEN1), and metastatic disease is an important cause of MEN1 ...
Neoplasms (7), Neuroendocrine Tumors (3), Multiple Endocrine Neoplasia Type 1 (2), more mentions
Nature medicine
This corrects the article DOI: 10.1038/nm.4219.
Neoplasms (1), more mentions
Radiology
Local Ablative Therapy Options for Patients with Inoperable Pancreatic Cancer: Response..
Oncology (2)
Pancreatic Neoplasms (2), more mentions
Annals of oncology : official journal of the European Society for Medical Oncology
... plus nimotuzumab (nimo), an anti-epidermal growth factor receptor monoclonal antibody, compared with gem plus placebo as first-line therapy in patients with advanced pancreatic cancer.Patients with previously untreated, unresectable, locally advanced or metastatic pancreatic cancer were randomly assigned to receive gem: 1000 mg/m2, 30-min i.v ...
Oncology (3)
Pancreatic Neoplasms (3), more mentions
Pancreas
Although the prognostic value of lymphocyte-to-monocyte ratio (LMR) has been recently demonstrated in solid tumors, little is known of its impact on advanced pancreatic cancer (APC. This study evaluates and validates the cutoff value of LMR for predicting palliative chemotherapy outcome using a transnational cohort of APC patients.A total of 405 APC patients receiving first-line palliative ...
Oncology (2)
Pancreatic Neoplasms (2), Neoplasms (1), more mentions
Pancreas
Pancreatic cancer is reported to be highly associated with thromboembolism (TE... for TE and its clinical impact in Japanese patients with pancreatic cancer.Data on consecutive pancreatic cancer patients receiving systemic chemotherapy between August 1999 and July 2015 ... was not uncommon in Japanese patients receiving chemotherapy for advanced pancreatic cancer and was associated with poor prognosis.
Oncology (7)
Pancreatic Neoplasms (5), Thromboembolism (3), more mentions
Journal of the National Cancer Institute
Editorial: Mendelian Randomization Analysis Identifies Body Mass Index and Fasting Insulin as Potential Causal Risk Factors for Pancreatic Cancer Risk..
Anti-Obesity and Weight Loss (2), Oncology (2)
Pancreatic Neoplasms (2), more mentions
Journal of the National Cancer Institute
Is the Women's Health Initiative (WHI) Dietary Modification Associated With a Reduced Risk of Pancreatic Cancer?.
Women's Health (2), Oncology (2)
Pancreatic Neoplasms (2), more mentions
Annals of oncology : official journal of the European Society for Medical Oncology
Borderline resectable pancreatic cancer: an evolving concept..
Oncology (2)
Pancreatic Neoplasms (2), more mentions
Pancreas
... was to investigate the role of Rab27A and Rab27B in the progression of pancreatic cancer.We down-regulated Rab27A and Rab27B expression in pancreatic cancer cell lines. The regulatory effects of knockdown Rab27A and Rab27B on pancreatic cancer cell were measured by cisplatin assay, invasion assay, proliferation assay, and Western blot ...
Oncology (5)
Pancreatic Neoplasms (4), Adenocarcinoma (1), Neoplasms (1), more mentions
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