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Endocrine Bone Diseases
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Your search returned 24 results
from the time period: last 90 days.
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Endocrine
The X-ray or computed tomography scan findings of osteitis fibrosa cystica include lytic or multilobular cystic changes... parathyroid hormone are virtually never seen AbstractText: When radiographic evidence of a lytic lesion and hypercalcemia are present, primary hyperparathyroidism should always be considered in the differential diagnosis Keyword: Osteitis fibrosa cystica.
Muscular and Skeletal Diseases (2), Oncology (1)
Hyperparathyroidism (11), Osteitis Fibrosa Cystica (3), Neoplasms (3), more mentions
Journal of the neurological sciences
The maid of the Bridal Room by Andrea Mantegna (1431-1506) shows evidence of hypopituitary dwarfism and neurofibromatosis type-1..
Dwarfism (2), Neurofibromatosis (2), more mentions
European journal of endocrinology
Bone turnover markers (BTMs) are useful in clinical practice as they are inexpensive, and they have proven useful for treatment monitoring and identification of poor adherence. BTMs cannot be used in individual patients for identifying accelerated bone loss or an increase in fracture risk or in deciding on the optimal therapy. They are useful for monitoring both anti-resorptive and anabolic treatment. Response can be defined as a result that exceeds an absolute target, or by a change greater than the least significant change; if such a response is not present, then poor compliance or secondary osteoporosis are likely causes. A baseline BTM measurement is not always made; in that case, a value of BTM on anti-resorptive treatment that is low or low normal or above the reference interval for anabolic therapy may be taken to indicate a satisfactory response. We provide an approach to using these bone turnover markers in clinical practice by describing algorithms for anti-resorptive and anabolic therapy and describing the changes we observe in the clinical practice setting.
Muscular and Skeletal Diseases (2), Endocrine Disorders (1)
Osteoporosis (1), Endocrine System Diseases (1), more mentions
The Journal of dermatology
Dyskeratosis congenita associated with congenital hypothyroidism..
Congenital Hypothyroidism (2), Dyskeratosis Congenita (2), more mentions
The Journal of dermatology
Abstract: There is no standard chemotherapeutic treatment for advanced extramammary Paget's disease, though the effectiveness of some chemotherapy regimens, including docetaxel, has ... 1 monotherapy was effective in two patients with advanced extramammary Paget's disease after docetaxel treatment failure... as the second-line treatment for patients with advanced extramammary Paget's disease Keyword: TS-1 monotherapy.
Muscular and Skeletal Diseases (5), more mentions
The Journal of dermatology
Abstract: A wide local excision is the standard treatment for extramammary Paget's disease (EMPD), though this treatment often leads to permanent anogenital mutilation and functional impairment... Keyword: extramammary Paget's disease. Keyword: imiquimod. Keyword: skin cancer. Keyword: topical treatment.
Muscular and Skeletal Diseases (3), Oncology (1)
Skin Neoplasms (1), more mentions
Gynecologic oncology
DescriptorName: Paget Disease, Extramammary... AbstractText: To determine surgical and pathologic variables associated with recurrence in extramammary Paget's disease (EMPD) AbstractText: Medical records of patients seeking care for EMPD from 1/1992-9/2015 were ... MMS should be explored to improve outcomes in gynecologic patients with EMPD Keyword: Extramammary Paget's disease.
Muscular and Skeletal Diseases (3), Oncology (2), Orphan Diseases (1)
Vulvar Neoplasms (1), Neoplasms (1), more mentions
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
In extramammary Paget disease (EMPD), initial margins of surgical excision are difficult to determine preoperatively. Fluorescence diagnosis (FD) may have utility as a noninvasive method for delineating tumor boundaries.The relationship between FD-delineated borders and results of multiple scouting biopsies (MSBs) in EMPD was investigated, evaluating the potential clinical role of FD.A cohort of 21 patients was studied ...
Neoplasms (1), more mentions
9. Invasive Paget Disease of the Vulva.  
Date: 10/04/2017
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Extramammary Paget disease of the vulva (EPDV) is a rare occurrence with an indolent and relapsing course. Progression to invasion occurs in 4% to 19% of cases. The aim of this study is to report clinical-pathological features and outcomes of patients treated for invasive EPDV.Data of consecutive patients treated between 2000 and 2017 for invasive EPDV were reviewed ...
Oncology (1)
Neoplasms (1), more mentions
Journal of the European Academy of Dermatology and Venereology : JEADV
Abstract: Dermoscopy has been reported to facilitate the diagnosis of extramammary Paget's disease (EMPD).(1-3) We report here the first application of dermoscope-guided lesional biopsy to confirm the diagnosis of EMPD. A 60-year-old male presented with a pruritic and painful rash over his left groin region for six months.
Muscular and Skeletal Diseases (2), Oncology (1)
Exanthema (1), Neoplasms (1), more mentions
Urology
AbstractText: To illustrate the heterogeneous care delivered to patients with extramammary Paget disease (EMPD), a rare and lethal malignancy with poorly described treatment methodologies, by characterizing the clinical and pathologic characteristics of an international patient support group AbstractText: Institutional review board approval was obtained to develop and distribute a nonvalidated ...
Erythema (1), Pruritus (1), more mentions
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
LETTER TO THE EDITOR: REGARDING DEEP N, BESCH-STOKES J, LANE J, DRISCOLL C, CARLSON M, "PAGET'S DISEASE OF THE TEMPORAL BONE: A SINGLE-INSTITUTION CONTEMPORARY REVIEW OF 27 PATIENTS"..
Muscular and Skeletal Diseases (2), more mentions
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
REPLY TO LETTER TO THE EDITOR: PAGET'S DISEASE OF THE TEMPORAL BONE, A SINGLE-INSTITUTION CONTEMPORARY REVIEW OF 27 PATIENTS..
Muscular and Skeletal Diseases (2), more mentions
Blood
Coexistence of multiple myeloma and Paget disease of bone..
Oncology (2)
Multiple Myeloma (2), Osteitis Deformans (2), more mentions
Oncotarget
Rarely, GCT could arise in bones affected by Paget's disease of bone (GCT/PDB. Although it is already known that GCT/PDB and GCT show a different clinical profile regarding the age-onset and skeletal localization, our deep clinical comparison between the two GCT/PDB and GCT cohorts, permitted us to identify additional differences (e.g.
Oncology (1), Muscular and Skeletal Diseases (1)
Giant Cell Tumor of Bone (2), Neoplasms (2), Bone Neoplasms (1), more mentions
Maturitas
The addition of zoledronic acid 4mg per six months to adjuvant endocrine therapy maintained and even increased bone mass during a 3-year treatment period and significantly improved disease-free survival in a population of young women who underwent menopause due to the adjuvant treatment. The major contributor to bone loss in the adjuvant treatment of breast cancer in postmenopausal ...
Oncology (16), Muscular and Skeletal Diseases (8), Women's Health (1)
Breast Neoplasms (14), Osteoporosis (3), Neoplasms (1), more mentions
Clinical genitourinary cancer
Advanced Scrotal Extramammary Paget's Disease Treated With Apatinib: A Case Report..
Muscular and Skeletal Diseases (2), more mentions
The breast journal
Eight patients showed a local relapse (11.6. One patient developed a recurrence within the nipple-areola region presented as Paget's disease (1.4. One patient presented a thorax wall relapse after 42 months of disease-free survival and died because of metastatic dissemination of the tumor. The DFS rate was 88.4% and the overall survival rate was 98.6.
Oncology (6), Muscular and Skeletal Diseases (1)
Noninfiltrating Intraductal Carcinoma (6), Neoplasms (6), Breast Neoplasms (5), more mentions
Clinical genitourinary cancer
Penile cancer was diagnosed in 5 patients (18.5%), of which 3 were squamous cell carcinoma (11.1%), 1 was metastasis of melanoma (3.7%), and 1 was extramammary Paget disease (3.7. In addition, 1 patient (3.7%) had a premalignant lesion on a condyloma, 12 (44.4%) had balanitis, 2 (7.4%) had psoriasis lesions, 3 (11.1%) had condylomas, 1 (3.7%) had genital melanosis, and ...
Oncology (4), Dermatology (3), Urology (1)
Balanitis (2), Penile Neoplasms (2), Squamous Cell Carcinoma (1), more mentions
Neuro-degenerative diseases
AbstractText: Mutations in the genes encoding the heterogeneous nuclear ribonucleoproteins hnRNPA1 and hnRNPA2/B1 have been reported in a multisystem proteinopathy that includes amyotrophic lateral sclerosis (ALS) and inclusion body myopathy associated with Paget disease of the bone and frontotemporal dementia. Mutations were also described in the prion-like domain of hnRNPA1 in patients with classic ALS.
Neurological and Central Nervous System Diseases (15), Neuroscience (2)
Amyotrophic Lateral Sclerosis (15), Frontotemporal Dementia (2), more mentions
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