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Prevention/Cardiovascular Risk
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Your search returned 34 results
from the time period: last 30 days.
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Clinical cardiology 
... expectations defined by gender roles contribute to gender differences in ASCVD risk factors. With these differing risk profiles, risk assessment, risk stratification, and primary preventive measures of ASCVD are different in women and men... The aim of this review article was to ultimately improve ASCVD primary prevention by reducing gender disparities through education of physicians Keyword: Cardiovascular Disease. Keyword: Disparities.
Cardiovascular Diseases (4), Endocrine Disorders (1), Immune System Diseases (1)
Cardiovascular Diseases (3), Gestational Diabetes (1), Pre-Eclampsia (1), more mentions
Journal of the American College of Cardiology 
... of proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors in secondary prevention of ASCVD... final results of cardiovascular outcomes trials in patients with clinical ASCVD and in a smaller number of high-risk primary prevention patients ... Revised recommendations are provided for patients with clinical ASCVD with or without comorbidities on statin therapy for secondary prevention.
Cardiovascular Diseases (8), Endocrine Disorders (1), Blood Disorders and Hematology (1)
Cardiovascular Diseases (2), Hyperlipoproteinemia Type II (1), Dyslipidemias (1), more mentions
Journal of the American Heart Association
AbstractText: The relative effect of hemoglobin A1c, blood pressure, and low-density lipoprotein-cholesterol (LDL-C) ("ABC" factors) on the prevention of cardiovascular diseases (CVD) among patients with type 2 diabetes mellitus is poorly understood. This study aimed to evaluate the association of key clinical parameters on CVD risk using a multifactorial optimal control approach in Chinese primary care patients ...
Cardiovascular Diseases (7), Endocrine Disorders (5)
Diabetes Mellitus, Type 2 (4), Cardiovascular Diseases (3), Heart Failure (2), more mentions
The Cochrane database of systematic reviews 
BACKGROUND: There is evidence from observational studies that whole grains can have a beneficial effect on risk for cardiovascular disease (CVD). Earlier versions of this review found mainly short-term intervention studies. There are now longer-term randomised controlled trials (RCTs) available. This is an update and expansion of the original review conducted in 2007. OBJECTIVES: The aim of this systematic review was to assess the effect of whole grain foods or diets on total mortality, cardiovascular events, and cardiovascular risk factors (blood lipids, blood pressure) in healthy people or people who have established cardiovascular disease or related risk factors, using all eligible RCTs. SEARCH METHODS: We searched CENTRAL (Issue 8, 2016) in the Cochrane Library, MEDLINE (1946 to 31 August 2016), Embase (1980 to week 35 2016), and CINAHL Plus (1937 to 31 August 2016) on 31 August 2016. We also searched on 5 July 2017 and the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) on 6 July 2017. We checked reference lists of relevant articles and applied no language restrictions. SELECTION CRITERIA: We selected RCTs assessing the effects of whole grain foods or diets containing whole grains compared to foods or diets with a similar composition, over a minimum of 12 weeks, on cardiovascular disease and related risk factors. Eligible for inclusion were healthy adults, those at increased risk of CVD, or those previously diagnosed with CVD. DATA COLLECTION AND ANALYSIS: Two review authors independently selected studies. Data were extracted and quality-checked by one review author and checked by a second review author. A second review author checked the analyses. We assessed treatment effect using mean difference in a fixed-effect model and heterogeneity using the I(2) statistic and the Chi(2) test of heterogeneity. We assessed the overall quality of evidence using GRADE with GRADEpro software. MAIN RESULTS: We included nine RCTs randomising a total of 1414 participants (age range 24 to 70; mean age 45 to 59, where reported) to whole grain versus lower whole grain or refined grain control groups. We found no studies that reported the effect of whole grain diets on total cardiovascular mortality or cardiovascular events (total myocardial infarction, unstable angina, coronary artery bypass graft surgery, percutaneous transluminal coronary angioplasty, total stroke). All included studies reported the effect of whole grain diets on risk factors for cardiovascular disease including blood lipids and blood pressure. All studies were in primary prevention populations and had an unclear or high risk of bias, and no studies had an intervention duration greater than 16 weeks.Overall, we found no difference between whole grain and control groups for total cholesterol (mean difference 0.07, 95% confidence interval -0.07 to 0.21; 6 studies (7 comparisons); 722 participants; low-quality evidence).Using GRADE, we assessed the overall quality of the available evidence on cholesterol as low. Four studies were funded by independent national and government funding bodies, while the remaining studies reported funding or partial funding by organisations with commercial interests in cereals. AUTHORS' CONCLUSIONS: There is insufficient evidence from RCTs of an effect of whole grain diets on cardiovascular outcomes or on major CVD risk factors such as blood lipids and blood pressure. Trials were at unclear or high risk of bias with small sample sizes and relatively short-term interventions, and the overall quality of the evidence was low. There is a need for well-designed, adequately powered RCTs with longer durations assessing cardiovascular events as well as cardiovascular risk factors.
Cardiovascular Diseases (6)
Cardiovascular Diseases (5), Myocardial Infarction (1), Unstable Angina (1), more mentions
Circulation research 
... cardiovascular disease, we review the proven, effective approaches to the prevention and treatment of cardiovascular disease... valvular heart disease, and symptomatic bradyarrhythmia; and approaches to the prevention of cardiovascular disease, including lifestyle factors, blood pressure control, cholesterol-lowering, antithrombotic ... We also discuss cardiovascular disease prevention in diabetes mellitus; digital health interventions; the importance of socioeconomic ...
Cardiovascular Diseases (15), Endocrine Disorders (1)
Cardiovascular Diseases (10), Atrial Fibrillation (2), Bradycardia (1), more mentions
Journal of hypertension
OBJECTIVE: There is little evidence to support an increased risk of blood pressure (BP) elevation among elderly individuals receiving antihypertensive drug treatment. METHODS: To clarify the impact on BP level and residual cardiovascular risk in treated elderly individuals, we analysed individual participant data of 26 133 residents aged 60-89 years from seven Japanese general populations and cross-classified participants by age category, 60-74 (young-old) versus 75-89 years (old-old), and by usage of antihypertensive medication at baseline survey (1980-1995). RESULTS: During a median follow-up period of 12.7 years, 2451 cardiovascular deaths were observed. Multivariable-adjusted hazard ratios of cardiovascular mortality in treated participants compared with untreated participants were 1.30 [95% confidence intervals, 1.16-1.46) and 1.35 (95% confidence interval, 1.16-1.56) in young-old and old-old participants, respectively. Irrespective of antihypertensive medication, the risk increase of total cardiovascular and stroke mortality with elevation of BP was significant among young-old (P ≤ 0.0013), but not significant among old-old participants (P ≥ 0.061). CONCLUSION: Although impact on BP was more evident among young-old than old-old individuals, clinicians who prescribe antihypertensive medication to elderly patients should consider that such patients require further monitoring.
Cardiovascular Diseases (1), more mentions
... 0.009) and 18% (p=0.004), respectively, over a total of 20-years of follow-up. Conclusions -The present analyses provide robust novel evidence for the short and long-term benefits of lowering LDL-C for the primary prevention of cardiovascular disease among individuals with primary elevations of LDL-C ≥190 mg/dL Keyword: cardiovascular disease prevention. Keyword: lipids and lipoproteins.
Cardiovascular Diseases (6)
Cardiovascular Diseases (4), Vascular Diseases (3), more mentions
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
... for 1 v 0 cardiovascular risk factors: HR, 1.63; 95% CI, 1.07 to 2.47; for ≥ 2 v 0 cardiovascular risk factors: HR, 2.86; 95% CI, 1.56 to 5.23; joint P < .01. Conclusion In a large, population-based cohort of NHL survivors, preexisting cardiovascular conditions were associated with increased risk of HF. Preventive approaches should take baseline cardiovascular health into account.
Oncology (6), Cardiovascular Diseases (3), Endocrine Disorders (1)
Heart Failure (2), Non-Hodgkin Lymphoma (2), Dyslipidemias (1), more mentions
The New England journal of medicine 
AbstractText: Rheumatic heart disease remains an important preventable cause of cardiovascular death and disability, particularly in low-income and middle-income countries. We estimated global, regional, and national trends in the prevalence of and mortality due to rheumatic heart disease as part of the 2015 Global Burden of Disease study AbstractText: We systematically reviewed data on fatal and nonfatal rheumatic ...
Cardiovascular Diseases (11)
Rheumatic Heart Disease (11), more mentions
The New England journal of medicine 
... whether treatment effects were reduced after 5 years or persisted for the remaining lifetime AbstractText: In this simulation study, intensive systolic blood-pressure control prevented cardiovascular disease events and prolonged life and did so at levels below common willingness-to-pay thresholds per QALY, regardless of whether benefits were reduced ...
Cardiovascular Diseases (5)
Cardiovascular Diseases (4), Hypertension (1), more mentions
Open heart 
No summary available
Coronary Artery Disease (1), Myocardial Infarction (1), more mentions
The New England journal of medicine 
Abstract: Background We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than aspirin alone for secondary cardiovascular prevention. Methods In this double-blind trial, we randomly assigned 27,395 participants with stable atherosclerotic vascular disease to receive rivaroxaban (2.5 mg twice daily) plus aspirin (100 mg once daily), rivaroxaban (5 mg twice daily), or aspirin ...
Cardiovascular Diseases (1)
Vascular Diseases (2), Myocardial Infarction (1), Cardiovascular Diseases (1), more mentions
The Canadian journal of cardiology
AbstractText: Guidelines on cardiovascular (CV) disease prevention promote healthy lifestyle behaviours and CV risk factor control to reduce CV risk. The effect of adherence to these guidelines on CV and all-cause mortality is not well known AbstractText: We assessed the effect of baseline adherence to "2016 European Guidelines on CV Disease Prevention in Clinical Practice" on long-term CV ...
Cardiovascular Diseases (1), Anti-Obesity and Weight Loss (1)
Cardiovascular Diseases (1), more mentions
Heart rhythm
BACKGROUND: Pericardial adhesions can prevent epicardial access and restrict catheter movement during mapping and ablation of ventricular tachycardia (VT) . The incidence of adhesions in patients without prior cardiac surgery or clinically evident pericarditis is not known. OBJECTIVE: To describe the incidence of pericardial adhesions in patients without prior cardiac surgery or pericarditis and explore their impact. METHODS: A retrospective search of our ablation database containing patients who underwent epicardial ablation for VT was undertaken. Adhesions were diagnosed with routine contrast pericardiography after pericardial entry. Demographics and long term outcomes were compared between patients with and without adhesions. RESULTS: Between 2004-2016, successful epicardial entry was achieved in 188/192 (98%) attempts. In 155 first time epicardial access attempts, pericardial adhesions were diagnosed in 13 (8%). When comparing baseline demographics, there were no significant differences. However, adhesions tended to occur more frequently with severe renal impairment (2% vs. 15%, p=0.07). No patients with structurally normal hearts had adhesions present. Adhesions were associated with limited epicardial mapping (3% vs. 85%, p<0.001) and lower acute procedural success (68% vs. 46%, p=0.02), but complication rates were similar. The presence of adhesions did not translate into lower VT free survival (p=0.64) or freedom from a combined end-point of VT recurrence, death or transplant at 1 year (p=0.93). CONCLUSION: Adhesions can be unexpectedly encountered in patients without prior cardiac surgery or pericarditis. When present, they can limit mapping and may associate with lower acute success. Larger studies are required to determine their impact on long-term outcomes.
Pericarditis (4), Tachycardia (2), more mentions
The significance of automatic implantable cardioverter-defibrillator (ICD) has been proven in subjects with preceding myocardial infarction and stark systolic left ventricular dysfunction (secondary prevention) AbstractText: In this case, we describe a female patient, 94 years old, with a dual-chamber pacemaker since 2014, normal functioning, and controlled hypertension. The patient was in use of bisoprolol 10 mg daily, hydrochlorothiazide ...
Cardiovascular Diseases (1)
Fistula (2), Hemothorax (2), Myocardial Infarction (1), more mentions
Journal of the American Heart Association
BACKGROUND: Given high rates of obesity, hypertension, and diabetes mellitus, black persons are at risk to develop heart failure. The association of moderate to vigorous physical activity (MVPA) and heart failure in black adults is underresearched. The purpose of this study was to explore whether greater MVPA was associated with lower risk of heart failure hospitalizations (HFHs) among black adults with normal ejection fractions. METHODS AND RESULTS: We performed a prospective analysis of 4066 black adults who participated in the Jackson Heart Study and who had physical activity measured, had normal ejection fraction on 2-dimensional echocardiograms, and were followed for 7 years for incident HFH. We used Cox proportional regression analyses adjusted for age, sex, body mass index, smoking status, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, coronary heart disease, atrial fibrillation, and chronic kidney disease and examined effect modification by sex and body mass index. Of the eligible population, 1925 participants, according to the duration of MVPA, had poor health (0 minutes/week), 1332 had intermediate health (1-149 minutes/week), and 809 had ideal health (≥150 minutes/week). There were 168 incident HFHs. MVPA for intermediate and ideal health was associated with decreasing risk of incident HFH (hazard ratio: 0.70 [95% confidence interval, 49-1.00] and 0.35 [95% confidence interval, 0.19-0.64], respectively; Ptrend=0.003). The full model revealed hazard ratios of 0.74 [95% confidence interval, 0.52-1.07] and 0.41 [95% confidence interval, 0.22-0.74], respectively. There was no effect modification between MVPA and body mass index or sex on incident HFH. CONCLUSIONS: A dose-response relationship between increasing levels of MVPA and protection from incident HFH was found in black men and women with normal ejection fractions.
Cardiovascular Diseases (4), Anti-Obesity and Weight Loss (4), Endocrine Disorders (2)
Heart Failure (5), Hypertension (2), Diabetes Mellitus (2), more mentions
Journal of the American Geriatrics Society
BACKGROUND/OBJECTIVES: We sought to determine whether statin use for primary prevention is associated with a lower risk of cardiovascular events or mortality in older men. DESIGN: Prospective cohort study. SETTING: Physicians' Health Study participants. PARTICIPANTS: 7,213 male physicians ≥70 years without a history of cardiovascular disease (CVD). MEASUREMENTS: Multivariable propensity score for statin use with greedy matching (1:1) to minimize confounding by indication. RESULTS: Median baseline age was 77 (70-102), median follow-up was 7 years. Non-users were matched to 1,130 statin users. Statin use was associated with an 18% lower risk of all-cause mortality, HR 0.82 (95% CI 0.69-0.98) and non-significant lower risk of CVD events, HR 0.86 (95% CI 0.70-1.06) and stroke, HR 0.70 (95% CI 0.45-1.09). In subgroup analyses, results did not change according to age group at baseline (70-76 or >76 years) or functional status. There was a suggestion that those >76 at baseline did not benefit from statins for mortality, HR 1.14 (95% CI 0.89-1.47), compared to those 70-76 at baseline, HR 0.83 (95% CI 0.61-1.11); however the CIs overlap between the two groups, suggesting no difference. Statin users with elevated total cholesterol had fewer major CVD events than non-users, HR 0.68 (95% CI 0.50-0.94) and HR 1.43 (95% CI 0.99-2.07)), respectively. CONCLUSIONS: Statin use was associated with a significant lower risk of mortality in older male physicians ≥70 and a nonsignificant lower risk of CVD events. Results did not change in those who were >76 years at baseline or according to functional status. There was a suggestion that those with elevated total cholesterol may benefit. Further work is needed to determine which older individuals will benefit from statins as primary prevention.
Cardiovascular Diseases (12)
Cardiovascular Diseases (2), more mentions
Journal of the American Heart Association
Self-care is defined as a naturalistic decision-making process addressing both the prevention and management of chronic illness, with core elements of self-care maintenance, self-care monitoring, and self-care management. In this scientific statement, we describe the importance of self-care in the American Heart Association mission and vision of building healthier lives, free of cardiovascular diseases and stroke. The evidence supporting specific self-care behaviors such as diet and exercise, barriers to self-care, and the effectiveness of self-care in improving outcomes is reviewed, as is the evidence supporting various individual, family-based, and community-based approaches to improving self-care. Although there are many nuances to the relationships between self-care and outcomes, there is strong evidence that self-care is effective in achieving the goals of the treatment plan and cannot be ignored. As such, greater emphasis should be placed on self-care in evidence-based guidelines.
Cardiovascular Diseases (6)
Cardiovascular Diseases (3), more mentions
BMJ open
AbstractText: To determine the cost-effectiveness of two bespoke severe mental illness (SMI)-specific risk algorithms compared with standard risk algorithms for primary cardiovascular disease (CVD) prevention in those with SMI AbstractText: Primary care setting in the UK. The analysis was from the National Health Service perspective AbstractText: 1000 individuals with SMI from The Health Improvement Network Database, aged 30 ...
Cardiovascular Diseases (3), Neuroscience (2), Anti-Obesity and Weight Loss (1)
Mental Disorders (2), Coronary Disease (1), Cardiovascular Diseases (1), more mentions
Correction to: Lifestyle Interventions to Prevent Cardiovascular Events After Stroke and Transient Ischemic Attack: Systematic Review and Meta-Analysis..
Cardiovascular Diseases (2)
Transient Ischemic Attack (2), more mentions
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