AbstractText: Benefits of granulocyte-macrophage colony-stimulating factor (GM-CSF) for improving walking ability in people with lower extremity peripheralarterydisease (PAD) are unclear. Walking exercise may augment the effects of GM-CSF in PAD, since exercise-induced ischemia enhances progenitor cell release and may promote progenitor cell homing to ischemic calf muscle AbstractText: To determine whether GM-CSF ...
... convertase subtilisin/kexin type 9) inhibitor evolocumab reduced low-density lipoprotein cholesterol and cardiovascular events in the FOURIER trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk. We investigated the efficacy and safety of evolocumab in patients with peripheralarterydisease (PAD) as well as the effect on major adverse limb events... Keyword: peripheralarterialdisease.
Abstract: Peripheralarterydisease (PAD) is one of the most common cardiovascular complications in patients with type 2 diabetes mellitus (T2DM)(1) and is a predictor of cardiovascular death.(2) Interventions that reduce cardiovascular complications in this patient population are urgently required... Keyword: peripheralarterydisease. Keyword: sodium-glucose cotransporter 2.
Endocrine Disorders (3) Peripheral Arterial Disease (3), Diabetes Mellitus, Type 2 (2), Heart Failure (1), more mentions
AbstractText: To determine the prevalence of sarcopenia in older men with peripheralarterialdisease (PAD) and to compare to a subset of the group to age, race, sex, and body mass index (BMI)-matched non-PAD control counterparts... Keyword: PeripheralArterialDisease. Keyword: Rehabilitation. Keyword: Sarcopenia.
Cardiovascular Diseases (14), Anti-Obesity and Weight Loss (1) Sarcopenia (10), Peripheral Arterial Disease (3), more mentions
OBJECTIVE: The numbers of lower extremity revascularisations and amputations are insufficiently reported in Norway. To support future policy decisions regarding the provision of vascular treatment, knowledge of such trends is important.
METHODS: This retrospective cross-sectional study from 2001 to 2014 used data from the Norwegian Patient Registry. The revascularisation treatments were categorised in multilevel, aortoiliac, femoral to popliteal and popliteal to foot levels and sorted as open, endovascular and hybrid. The sessions in amputations were divided in major (thigh and below knee) and minor (ankle, foot or digit). Incidence rates were assessed per 100 000 for patients in the age group >60 years. The diabetic prevalence was calculated and the endovascular numbers at the South-Eastern, Western, Central and Northern Norway Regional Health Authority were compared.
RESULTS: The overall revascularisation rates increased from 308.7 to 366.8 (p=0.02). Open revascularisations decreased from 158.9 to 98.7 (p<0.01) while endovascular revascularisations increased from 142.2 to 243.4 (p<0.01). Hybrid revascularisations increased from 7.4 to 24.8 (p<0.01). Major amputation rates decreased from 87.8 to 48.7 (p<0.01) while minor amputations increased from 12.3 to 19.6 (p=0.01). The diabetic percentages increased from 12.2 to 22.3 (p<0.01) in revascularisations, from 26.5 to 30.8 (p=0.02) in major amputations and from 43.0 to 49.3 (p=0.13) in minor. (p values refer to average annual changes.) The regional trends in endovascular treatments varied within and between the vascular groups.
CONCLUSION: From 2001 to 2014, the revascularisation rates increased due to the rise in endovascular procedures. Open revascularisations and major amputation rates decreased, minor increased. The regional variances in endovascular treatments indicate that the availability of this technology differed between the health regions of Norway. The increase in patients with diabetes requires continued awareness of diabetes and its complications.
AbstractText: To evaluate 2-year results of the Zilver PTX (Cook Medical, Bloomington, Indiana) drug-eluting stent (DES) for femoropopliteal peripheralarterydisease (PAD) in patients with no continuous patent infrapopliteal runoff arteries compared with patients with ≥ 1 continuous patent runoff vessels AbstractText: A retrospective analysis of patients with femoropopliteal ...
AbstractText: The aim was to examine whether allopurinol use is independently associated with a reduction in the risk of incident peripheralarterialdisease (PAD) in the US elderly AbstractText: We used the 5% random Medicare sample from 2006 to 2012 to examine the ... Keyword: peripheralarterialdisease. Keyword: peripheralvasculardisease.
Cardiovascular Diseases (10), Senior Health (4) Peripheral Arterial Disease (3), Peripheral Vascular Diseases (1), more mentions
DescriptorName: PeripheralArterialDisease... AbstractText: To describe the prevalence of PeripheralArteryDisease (PAD) in a random population sample and to evaluate its ... Our results show the existence of a low prevalence of peripheralarterydisease in a population aged 45-74 years... pressure and heart rate >90 bpm were strongly associated with peripheralarterydisease.
Cardiovascular Diseases (8), Endocrine Disorders (4) Peripheral Arterial Disease (6), Diabetes Mellitus, Type 2 (2), Prediabetic State (1), more mentions
Abstract: The burden and predictors of hospitalization over time in community-based patients with peripheralarterydisease (PAD) have not been established... Keyword: peripheralarterydisease (PAD. Keyword: vascular medicine.
All patients undergone above-the-knee amputation or below-the-knee amputation due to peripheralarterydisease between 1996 and 2010 were reviewed to evaluate post-operative opioid consumption and complications AbstractText: A total of 434 amputations in 323 patients were included in the study. The number of surgical complications, the need for surgical revision and the number of intensive ...
This study compared the time to peak intensity measured by CEUS in patients with peripheralarterialdisease (PAD) and healthy control participants AbstractText: After a comprehensive literature search in multiple electronic databases and study selection, a random-effect meta-analysis was performed to compare the time ... Keyword: peripheralarterialdisease.
AbstractText: Patients with peripheralarterialdisease (PAD) have increased risk on future cerebro- and cardiovascular events. Our aim was to examine whether carotid artery reactivity (CAR; a novel, simple procedure to examine endothelial function) predicts cardiovascular events in PAD patients AbstractText: Increased risk for future cardiovascular events in PAD patients is likely related to endothelial dysfunction, highlighting the necessity for ...
Cardiovascular Diseases (10) Peripheral Arterial Disease (2), more mentions
The diagnosis, surveillance, and management of infrapopliteal critical limb ischemia remain inconsistent among clinicians. This study demonstrates that using an absolute ankle pressure of >73 mm Hg or an absolute toe pressure increase of 1 mm Hg or greater post endovascular intervention in patients with infrapopliteal critical limb ischemia may be predictive of a reduction in target limb revascularization, amputation, and death. This study highlights the need for vascular societies to come together to promote standardized screening, surveillance, and treatment paradigms for this complex population.
Questions and answers on diagnosis and management of patients with PeripheralArterialDiseases: a companion document of the 2017 ESC Guidelines for the Diagnosis and Treatment of PeripheralArterialDiseases, in collaboration with the European Society for Vascular Surgery (ESVS ... ESO)The Task Force for the Diagnosis and Treatment of PeripheralArterialDiseases of the European Society of Cardiology (ESC) and of ...
Cardiovascular Diseases (2) Peripheral Arterial Disease (6), more mentions
Abstract: This study compares procedural complications and clinical outcomes between subintimal crossing versus intraluminal crossing during endovascular treatment of infrainguinal peripheral artery chronic total occlusions (CTO. We identified 1335 CTO interventions in 1001 patients from the multicenter Excellence in PeripheralArteryDisease (XLPAD) registry from January 2005 to October 2015... Keyword: peripheralarterydisease (PAD. Keyword: subintimal crossing technique.
Abstract: The resting ankle-brachial index (ABI) is a first-line test to diagnose peripheralarterydisease (PAD... Keyword: peripheralarterydisease (PAD. Keyword: randomized controlled trial (RCT. Keyword: teaching. Keyword: vascular medicine training.
... walking distance, and quality of life in comparison to baseline AbstractText: This study indicates that directional atherectomy in popliteal arteries leads to favorable technical and clinical results at 1 year for claudicant as well as CLI patients Keyword: amputation. Keyword: angioplasty. Keyword: atherectomy. Keyword: claudication. Keyword: critical limb ischemia. Keyword: patency. Keyword: peripheralarterydisease. Keyword: popliteal artery. Keyword: stent.
Ischemia (2), Intermittent Claudication (1), Pathologic Constriction (1), more mentions
... patency at 36 months were 54.2% and 68.1%, respectively AbstractText: In our experience, the Ocelot system would appear to be a safe and effective tool for increasing the applicability of endovascular techniques. However, the midterm results did not show drastic improvement Keyword: chronic total occlusions. Keyword: crossing device. Keyword: optical coherence tomography. Keyword: percutaneous peripheral intervention. Keyword: peripheralarterydisease.