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Cardiac Biomarkers
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Your search returned 7 results
from the time period: last 30 days.
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... subset of 517 epigenetic loci with DCM and cardiac gene expression. Furthermore, we identified distinct epigenetic methylation patterns that are conserved across tissues, rendering these CpGs novel epigenetic biomarkers for heart failure. Conclusions -The present study provides to our knowledge the first epigenome-wide association study in living patients with heart failure using a multi-omics approach Keyword: DNA Methylation.
Heart Failure (5), Dilated Cardiomyopathy (2), more mentions
European heart journal
Biotherapies and biomarkers for cardiovascular diseases: A 15-year journey at the ICREC (Heart Failure and Cardiac Regeneration) Research Laboratory in Barcelona, Spain..
Cardiovascular Diseases (2)
Heart Failure (2), Cardiovascular Diseases (2), more mentions
Clinical research in cardiology : official journal of the German Cardiac Society
Higher levels of PIIINP were independently associated with higher proportion of NP above the prespecified thresholds (HR = 1.95, 95% CI 1.16-3.29, p = 0.012) AbstractText: Eplerenone effectively reduces PIIINP levels when baseline values were above the median. Eplerenone may limit ECMM formation in post-MI without HF Keyword: Eplerenone. Keyword: Extracellular cardiac markers. Keyword: Myocardial infarction.
Myocardial Infarction (4), Heart Failure (2), Tachycardia (1), more mentions
PloS one
[This corrects the article DOI: 10.1371/journal.pone.0177809.].
Cardiovascular Diseases (1)
Atherosclerosis (1), more mentions
BACKGROUND: Radial artery intima-media thickness (rIMT) measured by ultra-high-resolution ultrasound is associated with increased cardiovascular risk and predicts outcomes. We performed non-invasive high-resolution ultrasound of the radial artery to investigate vascular changes in subjects presenting with acute coronary syndrome (ACS) and who had undergone percutaneous coronary intervention (PCI). PURPOSE: In the present work, we aimed to follow rIMT change over time post-acute coronary syndrome as a tool to monitor potential response to intensified medical therapy. METHODS: We examined 256 subjects who underwent PCI due to ACS and healthy controls (n= 39) and we measured a number of biomarkers, which are known to be associated with cardiovascular disease. Images of radial artery were acquired bilaterally in the longitudinal view using a 50 MHz transducer (Vevo 2100 VisualSonics, Inc, Toronto, Ontario, Canada). Carotid IMT (cIMT) and rIMT were measured at <1 month after index PCI followed by a repeated measurement of rIMT at 4 months from the ACS in a sub-set (n=117). RESULTS: rIMT measured within 1 month post ACS was significantly higher than rIMT after 4 months from ACS, (p < 0.0001), mean ± SD (rIMT right 0.35 ± 0.08; rIMT left 0.37 ± 0.08) vs. (rIMT right 0.29 ± 0.08; rIMT left 0.31 ± 0.09) respectively. There was no statistically significant change in cIMT. In healthy controls there were no changes in rIMT or cIMT overtime. High levels of CX3CL1 and myeloperoxidase measured within one month post ACS are associated with increase of rIMT, r=0.38 (p< 0.0001) and r=0.41 (p< 0.0001) respectively. CONCLUSIONS: rIMT seem to decrease systemically after ACS and is accompanied with corresponding biomarker change. The cause and clinical implications of the observed decrement in rIMT after ACS need further studies.
Cardiovascular Diseases (5)
Acute Coronary Syndrome (3), Cardiovascular Diseases (1), Atherosclerosis (1), more mentions
Cerebral Oximetry Leading up to Cardiac Arrest: A Marker of the Impact of Mean Arterial Pressure on the Brain, but not Time of Death..
Heart Arrest (2), more mentions
Heart (British Cardiac Society)
Serum biomarkers in valvular heart disease..
Cardiovascular Diseases (2)
Heart Valve Diseases (2), more mentions