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Your search returned 28 results
from the time period: last 30 days.
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The American journal of cardiology
In 6,811 participants from the Multi-Ethnic Study of Atherosclerosis, we used Cox models to examine if diastolic blood pressure category is associated with coronary heart disease events, stroke, and mortality ... pressure <60 mm Hg was associated with increased risk of coronary heart disease events and all-cause mortality in the sample overall, but this association appeared strongest in individuals with subclinical atherosclerosis ...
Cardiovascular Diseases (6)
Coronary Disease (3), Atherosclerosis (3), more mentions
Heart (British Cardiac Society)
We sought to examine the relation between VE and sudden cardiac death (SCD) in the Atherosclerosis Risk in Communities (ARIC) Study.The ARIC Study is a ... these findings did not remain significant after adjustment for established cardiovascular disease risk factors (HR 0.94, 95% CI 0.73 to 1.20 ... associated with an increased risk for SCD after adjustment for cardiovascular risk factors.
Cardiovascular Diseases (3)
Cardiac Sudden Death (2), Atherosclerosis (2), Cardiovascular Diseases (1), more mentions
The American journal of cardiology
... a nonspecific marker of systemic inflammation, in the development of coronary heart disease (CHD... ferritin with incident CHD, incident stroke, and subclinical measurements of atherosclerosis among blacks. For our prospective study, we utilized data from the Jackson Heart Study... ferritin and specific study covariates, including carotid intima-media thickness, coronary artery calcium, and abdominal aortic calcium, were obtained.
Cardiovascular Diseases (3)
Coronary Disease (1), Cardiovascular Diseases (1), Atherosclerosis (1), more mentions
The New England journal of medicine 
Abstract: Background Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein ... Conclusions Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo ...
Cardiovascular Diseases (2), Oncology (1)
Vascular Diseases (4), Myocardial Infarction (1), Neoplasms (1), more mentions
Journal of the American College of Cardiology 
... low-density lipoprotein (LDL)-cholesterol lowering in the management of atherosclerotic cardiovascular disease (ASCVD) risk... Most notably, the FOURIER (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk ... assessing evolocumab and bococizumab, respectively, have published final results of cardiovascular outcomes trials in patients with clinical ASCVD and in a ...
Cardiovascular Diseases (8), Endocrine Disorders (1), Blood Disorders and Hematology (1)
Cardiovascular Diseases (2), Hyperlipoproteinemia Type II (1), Dyslipidemias (1), more mentions
The American journal of cardiology
Abstract: Whether health checkups favorably impact the occurrence of atherosclerotic cardiovascular disease (ASCVD) and all-cause mortality in the general population remains in debate. We investigated further the impact of health checkups on hard ASCVD events and all-cause mortality. We compared the occurrence of hard ASCVD events and all-cause deaths for 4 years starting in 2010 between participants ...
Cardiovascular Diseases (3), Blood Disorders and Hematology (2)
Dyslipidemias (2), Cardiovascular Diseases (2), Myocardial Infarction (1), more mentions
Does inflammation matter in coronary artery disease. Is it a driving force in atherosclerosis, or merely an epiphenomenon... Indeed, the results of this trial open up a new avenue for cardiovascular prevention.
Cardiovascular Diseases (2)
Atherosclerosis (2), Coronary Artery Disease (1), more mentions
The New England journal of medicine 
... suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease... The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death... 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering.
Muscular and Skeletal Diseases (2), Cardiovascular Diseases (2)
Myocardial Infarction (2), Cardiovascular Diseases (1), Unstable Angina (1), more mentions
American heart journal
AbstractText: Cell adhesion molecules are key regulators of atherosclerotic plaque development, but circulating levels of soluble fragments, such as intercellular ... cell adhesion molecule (sVCAM-1), have yielded conflicting associations with atherosclerotic cardiovascular disease (ASCVD... soluble ESAM (sESAM) levels have been associated with prevalent subclinical atherosclerosis... ASCVD was defined as first myocardial infarction, stroke, coronary revascularization, or CV death.
Cardiovascular Diseases (2)
Myocardial Infarction (1), Cardiovascular Diseases (1), Atherosclerosis (1), more mentions
Annals of internal medicine 
... to evaluate the spatial relationship between neighborhood disadvantage and major atherosclerotic cardiovascular disease (ASCVD)-related events; second, to evaluate the relative extent ... occurrence of a major ASCVD event (myocardial infarction, stroke, or cardiovascular death) within 5 years, modeled as a function of a ... Model (PCERM) of the American College of Cardiology and American Heart Association.
Cardiovascular Diseases (3)
Cardiovascular Diseases (2), Myocardial Infarction (1), more mentions
Plaque rupture has dominated our thinking about ACS pathophysiology for decades. However, current evidence suggests that a sole focus on plaque rupture vastly oversimplifies this complex collection of diseases and obscures ... We propose segmenting coronary artery thrombosis caused by plaque rupture into cases with or without signs of concomitant inflammation ... Coronary artery thrombosis caused by plaque erosion may be on the rise in an era of ...
Cardiovascular Diseases (1)
Thrombosis (2), Myocardial Infarction (1), Atherosclerosis (1), more mentions
Heart (British Cardiac Society)
AbstractText: To determine factors associated with coronary artery disease (CAD) and ischaemic stroke in ageing adult congenital heart disease (ACHD) patients AbstractText: We performed a multicentre case-control ... In multivariable logistic regression analysis, traditional atherosclerotic risk factors (hypertension (OR 2.45; 95% CI 1.15 to 5.23 ... valves (OR 2.67; 95% CI 1.09 to 6.50) AbstractText: Traditional atherosclerotic risk factors were associated with CAD in ACHD patients.
Cardiovascular Diseases (4)
Heart Diseases (3), Coronary Artery Disease (3), Hypertension (1), more mentions
The New England journal of medicine 
... blind trial, we randomly assigned 27,395 participants with stable atherosclerotic vascular disease to receive rivaroxaban (2.5 mg twice daily) plus ... Conclusions Among patients with stable atherosclerotic vascular disease, those assigned to rivaroxaban (2.5 mg twice daily) plus aspirin had better cardiovascular outcomes and more major bleeding events than those assigned to ...
Cardiovascular Diseases (1)
Vascular Diseases (2), Myocardial Infarction (1), Cardiovascular Diseases (1), more mentions
... C ≥190 mg/dL are at a higher risk of atherosclerotic cardiovascular disease as a result of long-term exposure to markedly ... carried out post-hoc analyses from the West Of Scotland Coronary Prevention Study (WOSCOPS) randomised, placebo-controlled trial, and observational post ... benefits of lowering LDL-C for the primary prevention of cardiovascular disease among individuals with primary elevations of LDL-C ≥190 mg/dL Keyword: cardiovascular disease prevention ...
Cardiovascular Diseases (6)
Cardiovascular Diseases (4), Vascular Diseases (3), more mentions
Abstract: Background -Coronary artery calcium (CAC) is an established predictor of future major adverse atherosclerotic cardiovascular events in asymptomatic individuals ... pain (or dyspnea) and intermediate pre-test probability for obstructive coronary artery disease (CAD) were randomized to FT (exercise electrocardiography, nuclear ... Coronary computed tomographic angiography provided significantly better prognostic information compared to ...
Myocardial Infarction (2), Unstable Angina (2), Ischemia (1), more mentions
JAMA cardiology 
... Addition of evolocumab to standard background therapy including statins AbstractText: Cardiovascular events including myocardial infarction, ischemic stroke and cardiovascular death, quality-adjusted life-year (QALY), incremental cost-effectiveness ratio ... In the base case, using US clinical practice patients with atherosclerotic cardiovascular disease with low-density lipoprotein cholesterol levels of at least ...
Cardiovascular Diseases (8)
Cardiovascular Diseases (5), Myocardial Infarction (2), more mentions
Kidney international
... Galectin-3 has been proposed as a novel biomarker of heart failure and cardiac fibrosis, and may also be associated with fibrosis of other ... To determine this, we prospectively analyzed data from 9,148 Atherosclerosis Risk in Communities (ARIC) Study participants with measured plasma galectin ... 1996-98) and without prevalent chronic kidney disease (CKD) or heart failure.
Cardiovascular Diseases (5), Kidney Disease (3), Endocrine Disorders (1)
Fibrosis (3), Hypertension (3), Chronic Kidney Diseases (3), more mentions
Journal of controlled release : official journal of the Controlled Release Society 
AbstractText: Calcific atherosclerosis is a major challenge to intraluminal drug delivery in peripheral artery disease (PAD) AbstractText: We evaluated the effects of orbital atherectomy on intraluminal paclitaxel delivery to human peripheral arteries with substantial calcified plaque AbstractText: Diagnostic angiography and 3-D rotational imaging of five ... in diffusivity (p <0.001) AbstractText: These data illustrate that calcified plaque limited intravascular drug delivery, and controlled OAS treatment of calcific plaques resulted in greater drug permeability and improved adjunct drug delivery ...
Cardiovascular Diseases (2)
Atherosclerosis (2), Peripheral Arterial Disease (2), more mentions
... of eosinophil activity and degranulation, which has been linked to atherosclerosis and cardiovascular disease. We examined the relationship between ECP, carotid plaque, and incidence of stroke in a prospective population-based cohort ... 1.86 (95% confidence interval: 1.32-2.63) in subjects with carotid plaque and ECP in the top tertile, compared with those without plaque and ECP in the first or second tertiles.High ECP ...
Cardiovascular Diseases (7), Oncology (1)
Cardiovascular Diseases (1), Atherosclerosis (1), Neoplasms (1), more mentions
Journal of the American College of Cardiology
Abstract: Inflammation is a critical factor in early atherosclerosis and its progression to myocardial infarction... myocardial infarction and can be modulated with short-term therapies, such as statins, that mitigate cardiovascular risk... This contemporary review first strives to understand the diverse roles of immune cells implicated in atherogenesis... Keyword: cardiovascular imaging.
Cardiovascular Diseases (2)
Myocardial Infarction (2), Atherogenesis (1), Atherosclerosis (1), more mentions
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