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Lung Cancer
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Your search returned 16 results
from the time period: last 30 days.
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The New England journal of medicine 
... with previously untreated, EGFR mutation-positive advanced non-small-cell lung cancer (NSCLC... untreated, EGFR mutation-positive (exon 19 deletion or L858R) advanced NSCLC in a 1:1 ratio to receive either osimertinib (at ... in the first-line treatment of EGFR mutation-positive advanced NSCLC, with a similar safety profile and lower rates of serious ...
Oncology (2)
Lung Neoplasms (2), more mentions
The New England journal of medicine 
Immunotherapy for Unresectable Stage III Non-Small-Cell Lung Cancer..
Oncology (2)
Lung Neoplasms (2), more mentions
The Lancet. Oncology 
AbstractText: Adjuvant chemotherapy for resected early-stage non-small-cell lung cancer (NSCLC) provides a modest survival benefit... addition of bevacizumab to adjuvant chemotherapy in early-stage resected NSCLC AbstractText: We did an open-label, randomised, phase 3 trial ... defined by the American Joint Committee on Cancer 6th edition) NSCLC.
Oncology (7), Cardiovascular Diseases (1)
Neoplasms (3), Lung Neoplasms (2), Hypertension (1), more mentions
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 
... radiotherapy (SBRT) for patients with early-stage non-small-cell lung cancer... for Stereotactic Body Radiotherapy for Early-Stage Non-Small-Cell Lung Cancer was reviewed for developmental rigor by methodologists... Recommendations For standard operative risk patients with stage I NSCLC, SBRT is not recommended outside of a clinical trial.
Oncology (8)
Lung Neoplasms (3), Neoplasms (3), more mentions
The Lancet. Oncology 
... or ROS proto-oncogene 1 (ROS1)-rearranged non-small-cell lung cancer (NSCLC) are sensitive to tyrosine kinase inhibitor (TKI) therapy, but resistance ... mutations, in patients with advanced ALK-positive or ROS1-positive NSCLC AbstractText: In this international multicentre, open-label, single-arm, first ... study, eligible patients had advanced ALK-positive or ROS1-positive NSCLC and were older than 18 years, with an Eastern Cooperative ...
Oncology (3)
Lung Neoplasms (2), Peripheral Nervous System Diseases (1), Lymphoma (1), more mentions
The Lancet. Oncology 
... therapy in patients with treatment-naive, advanced non-small-cell lung cancer (NSCLC) with a programmed cell death-ligand 1 (PD-L1) tumour ... 3 trial, we recruited patients with treatment-naive, stage IV NSCLC in 102 sites in 16 countries... 30 items (QLQ-C30), the EORTC Quality of Life Questionnaire Lung Cancer 13 items (QLQ-LC13), and the European Quality of Life ...
Oncology (4)
Lung Neoplasms (2), Neoplasms (1), Cough (1), more mentions
Advances in radiation oncology 
AbstractText: Guidelines for locally advanced non-small cell lung cancer (LA-NSCLC) recommend definitive chemoradiation therapy (CRT) for cN2-N3 disease, reserving ... trimodality therapy receipt and determined outcomes in patients with LA-NSCLC who were treated with definitive doses (≥60 Gy) of neoadjuvant ... surgery AbstractText: We retrospectively analyzed 355 consecutive patients with LA-NSCLC who were treated with curative intent between January 2000 and ...
Oncology (2)
Lung Neoplasms (2), Chronic Obstructive Pulmonary Disease (1), more mentions
Annals of oncology : official journal of the European Society for Medical Oncology 
... and represent a major cause of morbidity and mortality in cancer. Coagulation inhibition with low molecular weight heparin (LMWH) may improve survival specifically in small cell lung cancer (SCLC) patients by preventing VTE and tumor progression; however, randomized trials with well-defined patient populations are needed to obtain conclusive data... NCT00717938 Keyword: Small cell lung cancer. Keyword: coagulation.
Oncology (10), Cardiovascular Diseases (2)
Lung Neoplasms (3), Neoplasms (3), Venous Thromboembolism (2), more mentions
... in human leukocyte antigen (LOHHLA), a computational tool to determine HLA allele-specific copy number from sequencing data. Using LOHHLA, we find that HLA LOH occurs in 40% of non-small-cell lung cancers (NSCLCs) and is associated with a high subclonal neoantigen burden, APOBEC-mediated mutagenesis, upregulation of cytolytic activity, and PD-L1 positivity... Keyword: lung cancer. Keyword: neoantigen.
Oncology (4)
Neoplasms (3), Lung Neoplasms (2), Chromosomal Instability (1), more mentions
Nature genetics 
... protein product (for example, EGFR-inhibitor treatment in EGFR-mutant lung cancers... Through genomic analysis of 1,122 EGFR-mutant lung cancer cell-free DNA samples and whole-exome analysis of seven ... longitudinally collected tumor samples from a patient with EGFR-mutant lung cancer, we identified critical co-occurring oncogenic events present in most advanced-stage EGFR-mutant lung cancers ...
Oncology (5)
Neoplasms (4), Lung Neoplasms (3), more mentions
The Annals of thoracic surgery 
AbstractText: Surgical resection with lobectomy is recommended for T1/T2 N0 small cell lung cancer (SCLC) patients after negative mediastinal staging. We sought to characterize variation in surgical therapy for early SCLC and determine the effect of a hospital's practice patterns on patient survival AbstractText: The National Cancer Database was examined from 2004 to 2013.
Oncology (8)
Neoplasms (4), Lung Neoplasms (2), more mentions
The Annals of thoracic surgery 
... treatments are evolving rapidly for stage I non-small cell lung cancer (NSCLC... 2000 and 2010 and that survival improved for stage I NSCLC patients over the same time period... measure was 2-year risk of death for stage I NSCLC AbstractText: Between 2000 and 2010, 40,589 patients (62%) underwent ...
Oncology (2)
Lung Neoplasms (2), more mentions
International journal of radiation oncology, biology, physics 
AbstractText: To investigate, in the setting of stereotactic ablative radiation therapy (SABR) for early-stage non-small cell lung cancer, the incidence and patterns of change in high-risk radiologic features (HRFs) in patients known to have no local recurrence AbstractText: Computed tomography (CT) scans of patients treated using volumetric ...
Oncology (2)
Lung Neoplasms (2), more mentions
Genome medicine 
... targeted NGS on 932 clinical cases of non-small-cell lung cancers (NSCLCs) using the Ion AmpliSeq™ Cancer Hotspot panel v2 assay ... a high level of JAK2 expression in a panel of NSCLC cell lines is correlated with increased sensitivity to a selective ... revealed JAK2 gain or loss due to genetic alterations in NSCLC clinical samples are associated with significantly elevated or reduced PD ...
Oncology (10)
Neoplasms (10), Lung Neoplasms (1), more mentions
The European respiratory journal 
Abstract: Occupational exposure constitutes a common risk factor for lung cancer... molecular patterns and occupational exposure.BioCAST was a cohort study of lung cancer in never-smokers that reported risk factor exposure and molecular patterns ... we conclude that occupational exposure slightly affects the molecular pattern of lung cancers in never-smokers.
Oncology (3)
Lung Neoplasms (3), more mentions
Science translational medicine 
... a major challenge in the treatment of non-small cell lung cancer (NSCLC... whereby stress hormones activate β2-adrenergic receptors (β2-ARs) on NSCLC cells, which cooperatively signal with mutant EGFR, resulting in the ... was associated with a worse outcome in EGFR TKI-treated NSCLC patients, and β-blocker use was associated with lower IL ...
Oncology (1)
Neoplasms (2), Lung Neoplasms (1), more mentions