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Leukemia Myeloproliferative Disorders
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Acute Myeloid Leukemia (AML) is the most common type of acute leukemia in adults. Median at at presentation is around 65 years. Symptoms are usually related to bone marrow failure, including fatigue, fever, bruising, or bleeding. Most patients present with pancytopenia and circulating blast forms. Patients with a high blast percentage are at risk for leukostasis, manifested by dyspnea, chest pain, headaches, confusion, and cranial nerve palsies. From the Washington Manual of Medical Therapeutics, 35e

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 
Abstract: Purpose Bosutinib is a potent dual SRC/ABL kinase inhibitor approved for adults with Philadelphia chromosome-positive chronic myeloid leukemia (CML) resistant and /or intolerant to prior therapy. We assessed the efficacy and safety of bosutinib versus imatinib for first-line treatment of chronic-phase CML. Methods In this ongoing, multinational, phase III study, 536 patients with newly diagnosed ...
Oncology (2)
Philadelphia Chromosome (4), Chronic BCR-ABL Positive Myelogenous Leukemia (2), Diarrhea (1), more mentions
American journal of respiratory and critical care medicine 
Predicting Corticosteroid Response in Chronic Obstructive Pulmonary Disease. Blood Eosinophils Gain Momentum..
Chronic Obstructive Pulmonary Disease (2), more mentions
The Lancet. Respiratory medicine 
Blood eosinophil counts showed a weak but significant association with sputum eosinophil counts (receiver operating characteristic area under the curve of 0 ... a broad range of COPD severity, high concentrations of sputum eosinophils were a better biomarker than high concentrations of blood eosinophils to identify a patient subgroup with more severe disease, more ...
Chronic Obstructive Pulmonary Disease (12), Emphysema (3), Dyspnea (1), more mentions