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Bone Marrow/Stem Cell Transplantation
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Your search returned 50 results
from the time period: last 90 days.
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 
DescriptorName: Hematopoietic Stem Cell Transplantation... Purpose Inpatient palliative care integrated with transplant care improves patients' quality of life (QOL) and symptom burden during hematopoietic stem-cell transplant (HCT... with the Hospital Anxiety and Depression Scale and Patient Health Questionnaire, PTSD checklist, and Functional Assessment of Cancer Therapy-Bone Marrow Transplant.
Neuroscience (5), Stem Cell Research (1), Oncology (1)
Post-Traumatic Stress Disorders (7), Depressive Disorder (5), Hematologic Neoplasms (2), more mentions
The New England journal of medicine 
DescriptorName: Hematopoietic Stem Cell Transplantation... Despite high rates of complete response after initial immunochemotherapy followed by autologous stem-cell transplantation, patients have relapses... assigned 240 patients to receive rituximab maintenance therapy or to undergo observation after autologous stem-cell transplantation (120 patients per group); 59 patients did not undergo randomization.
Mantle-Cell Lymphoma (3), Allergy (1), Lymphoma (1), more mentions
The Journal of infectious diseases
AbstractText: The efficiency and mechanisms of adoptive transfer of cytomegalovirus (CMV)specific T cells for refractory CMV infection after haploidentical stem cell transplantation (haplo-SCT) remain largely unknown AbstractText: Thirty-two patients with refractory CMV infection who accepted treatment with adoptive CMV-specific T-cell ... Keyword: haploidentical stem cell transplantation.
Stem Cell Research (3), Immune System Diseases (1)
Infections (4), Cytomegalovirus Infections (2), more mentions
Cell reports 
Systems-level analyses offer increased power to sort patients on the basis of coordinated changes across immune cells and proteins. Allogeneic stem cell transplantation is a well-established form of immunotherapy whereby a donor immune system induces a graft-versus-leukemia response... Keyword: bone marrow transplantation... Keyword: stem cell transplantation. Keyword: systems immunology.
Oncology (3)
Leukemia (3), Infections (1), Neoplasms (1), more mentions
The Journal of infectious diseases
Abstract: As a live attenuated vaccine, Yellow fever vaccine (YFV) is not routinely performed after allogeneic hematopoietic stem cell transplant (HSCT) despite it being the only efficient preventive therapy. We retrospectively identified 21 HSCT recipients immunized with YFV at a median of 39 months after HSCT and a median of 33 months after withdrawal of immunosuppression without any side effects.
Vaccines (4)
Yellow Fever (3), more mentions
... nodosa, lacunar ischemic strokes and intracranial hemorrhages), immunodeficiency and bone marrow failure. TNF-α blockade is the treatment of choice for the autoinflammation and vascular manifestations. Hematopoietic stem cell transplantation (HSCT) represents a potential definitive treatment. We present a cohort of 14 patients from 6 countries who received HSCT for DADA2. Indication for HSCT was bone marrow dysfunction or immunodeficiency.
Stem Cell Research (2)
Intracranial Hemorrhages (1), Polyarteritis Nodosa (1), Stroke (1), more mentions
Annals of oncology : official journal of the European Society for Medical Oncology
Therefore, new technologies to assess deeper response are required.We retrospectively analyzed 125 patients with MM who underwent high-dose melphalan plus autologous stem cell transplantation (ASCT) to detect MRD in autograft/bone marrow (BM) cells using a next-generation sequencing (NGS)-based method and allele-specific oligonucleotide-polymerase chain ...
Stem Cell Research (2), Oncology (2)
Multiple Myeloma (2), Residual Neoplasm (2), more mentions
American journal of kidney diseases : the official journal of the National Kidney Foundation
Acute Kidney Injury and Nephrotic-Range Proteinuria in a Patient 18 Months After Bone Marrow Transplantation..
Acute Kidney Injury (2), Proteinuria (2), more mentions
Journal of neurology, neurosurgery, and psychiatry
Autologous haematopoietic stem cell transplantation is a treatment approach that aims to ameliorate and to ... Available data suggest that autologous haematopoietic stem cell transplantation is superior to conventional treatment in terms of efficacy with ... current data on clinical effect and safety of autologous haematopoietic stem cell transplantation for neurological disease are reviewed Keyword: clinical neurology.
Stem Cell Research (5), Immune System Diseases (3), Neuroscience (1)
Multiple Sclerosis (3), Polyneuropathies (1), Myasthenia Gravis (1), more mentions
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
AbstractText: Gram-negative bacteremia (GNB) is a major cause of illness and death after hematopoietic stem cell transplantation (HSCT), and updated epidemiological investigation is advisable AbstractText: We prospectively evaluated the epidemiology of pre-engraftment GNB in 1118 allogeneic HSCTs (allo-HSCTs) and 1625 autologous HSCTs (auto ... Keyword: stem cell transplant.
Oncology (1)
Infections (3), Bacteremia (3), Neutropenia (1), more mentions
The Cochrane database of systematic reviews
... of the disease involves a choice from enzyme replacement therapy, substrate reduction therapy and hemotopoietic stem cell transplantation (HSCT... these sites: 02 March 2017 AbstractText: All randomised, quasi-randomised and controlled clinical trials comparing stem cell transplantation with enzyme replacement therapy, substrate reduction therapy, symptomatic treatment or no treatment in people with ...
Stem Cell Research (3)
Cystic Fibrosis (1), Inborn Metabolism Errors (1), Neurologic Manifestations (1), more mentions
The Journal of allergy and clinical immunology
Long term immune reconstitution after matched unrelated hematopoietic stem cell transplantation for immunodeficiency..
Nature communications 
Abstract: Allogeneic hematopoietic stem cell transplantation (HSCT) is a critically important therapy for hematological malignancies, inborn errors of metabolism, and immunodeficiency disorders, yet complications such as graft-vs.-host disease (GvHD) limit survival. Development of anti-GvHD therapies that do not adversely affect susceptibility to infection or graft-vs.-tumor immunity are hampered by the lack of a physiologically relevant ...
Stem Cell Research (2)
Hematologic Neoplasms (1), Hematologic Diseases (1), Infections (1), more mentions
The Lancet. Oncology
Rituximab and autologous stem-cell transplantation for high-risk diffuse large B-cell lymphoma..
Diffuse Large B-Cell Lymphoma (2), more mentions
The Lancet. Oncology
Rituximab and autologous stem-cell transplantation for high-risk diffuse large B-cell lymphoma - Authors' reply..
Diffuse Large B-Cell Lymphoma (2), more mentions
The Journal of antimicrobial chemotherapy
Objectives: To assess therapeutic levels, safety and tolerability of a novel formulation SUBA-itraconazole (where SUBA stands for SUper BioAvailability) when compared with conventional itraconazole liquid when used as antifungal prophylaxis in patients undergoing allogeneic HSCT or in haematological malignancy patients with an intermediate/high risk of invasive fungal infection (IFI). Methods: This was a single-institution, prospective cohort study using a historical control group as the comparator. Results: A total of 57 patients were assessed: 27 in the SUBA-itraconazole cohort and 30 in the liquid itraconazole cohort. Therapeutic concentrations were achieved significantly more quickly in the SUBA-itraconazole group: median of 6 (95% CI 5-11) days versus 14 (95% CI 12-21) days in the liquid itraconazole group ( P  <   0.0001). At day 10, therapeutic concentrations were achieved in 69% (95% CI 44%-81%) of the SUBA-itraconazole group versus 21% (95% CI 7%-33%) of the liquid itraconazole group ( P  <   0.0001). The mean trough serum concentrations at steady-state of SUBA-itraconazole were significantly higher, with less interpatient variability [1577 ng/mL, coefficient of variation (CV) 35%] versus liquid itraconazole (1218 ng/mL, CV 60%) ( P  <   0.001). There were two (7.4%) treatment failures in the SUBA-itraconazole group, both due to cessation of therapy for mucositis, compared with seven (23.3%) treatment failures in the liquid itraconazole group, due to subtherapeutic levels (five), mucositis (one) and gastrointestinal intolerance (one) ( P  =   0.096). Conclusions: The use of the SUBA-itraconazole formulation was associated with more rapid attainment of therapeutic levels with less interpatient variability compared with conventional liquid itraconazole when used as IFI prophylaxis in allogeneic HSCT or intermediate-/high-IFI risk haematological malignancy patients.
Stem Cell Research (1)
Mucositis (2), Infections (1), more mentions
The British journal of dermatology
We aimed at assessing the efficacy of autologous haematopoietic stem cell transplantation (HSCT) for skin sclerosis and lung function in systemic sclerosis (SSc. We performed a systematic literature review in the Pubmed and Scopus databases from the earliest records to March 2016. We assessed quality using the Cochrane tool for randomized studies, Newcastle-Ottawa scale for controlled-cohort studies and ...
Stem Cell Research (2)
Systemic Scleroderma (2), Fibrosis (1), Sclerosis (1), more mentions
Nature medicine
The enteric virome in hematopoietic stem cell transplantation: ready for its close-up..
Stem cell transplantation in Krabbe disease: New truths discovered and opinions change..
Diffuse Globoid Body Sclerosis (2), more mentions
Abstract: Leukemia relapse remains the major cause of allogeneic hematopoietic stem cell transplantation (HCT) failure and the prognosis for patients with post-HCT relapse is poor. There is compelling evidence that potent selective anti-leukemic effects can be delivered by donor T cells specific for particular minor histocompatibility (H) antigens.
Oncology (4)
Leukemia (4), more mentions
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