Four of 192 treatments (2%) demonstrated local tumor recurrence or progression at the time of analysis. Of the 4 local failures, 1 patient had kyphoplasty prior to SRS. This recurrence occurred 18 months after SRS in the setting of widespread systemic disease and spinaltumor progression... Keyword: spinetumors. Keyword: stereotactic radiosurgery.
Oncology (2) Neoplasms (7), Spinal Cord Compression (1), more mentions
AbstractText: We quantified 378 HRMAS 1H NMR spectra of human braintumours (132 glioblastomas, 101 astrocytomas, 75 meningiomas, 37 oligodendrogliomas and 33 metastases) from the eTumour database and looked for metabolic interactions by metabolite-metabolite correlation analysis (MMCA) AbstractText: All tumour types showed remarkably similar metabolic correlations. Lactate correlated positively with alanine, glutamate with glutamine; creatine + phosphocreatine (tCr) correlated positively ...
Oligodendroglioma (2), Glioblastoma (1), Astrocytoma (1), more mentions
Abstract: Glioblastoma (GBM) is the most common primary braincancer in adults and is notoriously difficult to treat because of its diffuse nature. We performed single-cell RNA sequencing (RNA-seq) on 3,589 cells in a cohort of four patients. We obtained cells from the tumor core as well as surrounding peripheral tissue.
Abstract: OBJECTIVE Glioma is the most common form of braintumor and has high lethality. The authors of this study aimed to elucidate the efficiency of preoperative inflammatory markers, including neutrophil/lymphocyte ratio (NLR), derived NLR (dNLR), platelet/lymphocyte ratio (PLR), lymphocyte/monocyte ratio (LMR), and prognostic nutritional index (PNI), and their paired combinations as tools for the preoperative diagnosis ...
Neurological and Central Nervous System Diseases (5), Oncology (2) Glioma (16), Epilepsy (5), Acoustic Neuroma (5), more mentions
... range [IQR] 5 days); 2 days after chest x-ray for chest pain (IQR 3) or MRI or CT for back pain (IQR 2); and 1 day after chest x-ray for pneumonia (IQR 2), MRI or CT for braintumor (IQR 2), or CT for cancer treatment (IQR 3.
Oncology (3), Neuroscience (1) Neoplasms (2), Back Pain (1), Brain Neoplasms (1), more mentions
Abstract: Glioblastoma has a gigantic unmet medical need. Molecular knowledge has evolved substantially, including data on clonal selection with progression. Past trials for all-comers may have produced false negative results. Molecular precision at progression needs workup of new tissue and revisiting drugs with focus on braintumor penetration may yield surprises.
Oncology (1) Glioblastoma (2), Brain Neoplasms (1), more mentions