... The study aims to elucidate the state of gender equality in epilepsy research, analyzing the representation of female authorships from 2008 to 2016 ... AbstractText: Gendermetrics aided in analyzing 106,282 authorships from 22,180 epilepsy-related original research articles... 2026 AbstractText: The integration of women in the scientific field of epilepsy is advanced.
Neurological and Central Nervous System Diseases (4) Epilepsy (4), more mentions
The authors' objectives were to establish the frequencies of epilepsy, headache, and abdominal pain and determine their impact on patient ... Provoked epilepticseizures were excluded... New-onset epilepsy and new AED treatment after surgery/virtual surgery were more common in INPH (epilepsy, 2.3% [INPH] vs 0.0% [control], p = 0.011; AED, 8.5% [INPH ...
Neurological and Central Nervous System Diseases (11) Epilepsy (11), Headache (9), Normal Pressure Hydrocephalus (3), more mentions
AbstractText: Following our original description of generalized epilepsy with febrile seizures plus (GEFS+) in 1997, we analyze the ... without preceding febrile seizures (16/409 [4%]), classic genetic generalized epilepsies (22/409 [5%]), and afebrile generalized tonic-clonic seizures (9 ... gene AbstractText: As 37/409 (9%) affected individuals have focal epilepsies, we suggest that GEFS+ be renamed genetic epilepsy with febrile seizures plus rather than generalized epilepsy with febrile seizures plus ...
Neurological and Central Nervous System Diseases (4) Febrile Seizures (7), Epilepsy (2), Generalized Epilepsy (2), more mentions
... in duration), due to the potential risks of continued uncontrolled epilepsy for that period. The first meeting of the Research Roundtable in Epilepsy on May 19-20, 2016, focused on "Reducing placebo exposure in epilepsy clinical trials," with a goal of considering new designs for epilepsy regulatory trials that may be added to the overall development ...
Neurological and Central Nervous System Diseases (6) Epilepsy (6), more mentions
It is now established that epilepsy is characterized by periodic dynamics that increase seizure likelihood at certain times of day, and which are highly patient-specific... to improve seizure prediction algorithms through straightforward, patient-specific modifications provides promise for increased quality of life and improved safety for patients with epilepsy.
Neurological and Central Nervous System Diseases (3) Seizures (8), Epilepsy (3), more mentions
... diagnoses from a single center, we used logistic and Poisson regression to compare the total number of comorbidities, number of medications, and presence of specific comorbidities in five mutually exclusive groups of diagnoses: epilepticseizures (ES) only, PNES only, mixed PNES and ES, physiologic nonepileptic seizurelike events, and inconclusive monitoring.
Neurological and Central Nervous System Diseases (1), Endocrine Disorders (1), Oncology (1) Seizures (5), Epilepsy (2), Chronic Pain (1), more mentions
... by the onset of prolonged febrile and afebrile seizures in infancy, and evolving to drug-resistant epilepsy with accompanying cognitive, behavioral, and motor impairment... Increasingly, a tendency is noted to define newly described epilepticdisorders primarily in genetic terms, with clinical features being linked to genotypes... Keyword: Fever-sensitive epilepsy.
Neurological and Central Nervous System Diseases (2) Severe Infantile Myoclonic Epilepsy (3), Epilepsy (2), Seizures (1), more mentions
To identify structural and/or metabolic alterations in patients with sleep-related hypermotor epilepsy (SHE) using magnetic resonance imaging (MRI) and proton MR spectroscopy (1H-MRS).Nineteen SHE patients (seven males; 34.7 ± 9.7 years, mean age ± standard deviation) and 17 matched healthy volunteers (seven males; 34.0 ± 8.9 years) were included ...
Neurological and Central Nervous System Diseases (2) Seizures (7), Epilepsy (2), more mentions
Recent Advances in Epilepsy Surgery and Achieving Best Outcomes Using High-Frequency Oscillations, Diffusion Tensor Imaging, Magnetoencephalography, Intraoperative Neuromonitoring, Focal Cortical Dysplasia, and Bottom of Sulcus Dysplasia..
Neurological and Central Nervous System Diseases (2) Cortical Dysplasia (2), Epilepsy (2), more mentions
... Surgical treatment can bring seizure remission in people with focal epilepsy but requires careful selection of candidates AbstractText: To determine which ... We audited seizure outcome of 693 adults who had resective epilepsy surgery between 1990 and 2010 and used survival analysis to ... People with an older onset of epilepsy had a higher probability of seizure recurrence (1.01; 95% CI ...
Neurological and Central Nervous System Diseases (7) Seizures (11), Epilepsy (6), Convulsive Seizures (2), more mentions
... patterns of presentation of neurocysticercosis (NCC) and its relationship with epilepsy in community-dwellers aged ≥20 years living in Atahualpa (rural ... Forty-one persons with epilepsy (PWE) were identified, for a crude prevalence of epilepsy of 28 per 1,000 population (95% confidence interval [CI ... three times the odds of having NCC than those without epilepsy, providing robust epidemiological evidence favoring the relationship between NCC and epilepsy Keyword: Cysticercosis ...
Neurological and Central Nervous System Diseases (10) Epilepsy (10), Neurocysticercosis (3), Cysticercosis (1), more mentions
Abstract: We examined cognition in aging persons with chronic epilepsy; characterized targeted vascular, inflammatory, and metabolic risk factors associated with ... Participants included 40 persons with chronic localization-related epilepsy and 152 controls, aged 54.6 and 55.3, respectively... Epilepsy participants exhibited impairment across all cognitive factor scores (all p's ... Aging persons with chronic epilepsy exhibit multiple abnormalities in metabolic, inflammatory, and vascular health that ...
Neurological and Central Nervous System Diseases (5), Neuroscience (4), Endocrine Disorders (3) Epilepsy (4), Insulin Resistance (3), Obesity (2), more mentions
... of cortical development related to neuronal migration disorders, frequently associated with drug-resistant epilepsy (DRE... Inclusion criteria were the following: (1) patients with epilepsy and PNHs (unilateral or bilateral, single or multiple nodules) diagnosed on brain magnetic ... and very effective diagnostic and therapeutic approach for DRE related to PNHs Keyword: Epilepsy surgery.
Neurological and Central Nervous System Diseases (3) Epilepsy (3), Periventricular Nodular Heterotopia (2), Neuronal Migration Disorders (1), more mentions
AbstractText: Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is a common epilepsy syndrome that is often poorly controlled by antiepileptic drug (AED) treatment... retention, efficacy, and tolerability in a cohort of patients with MTLE-HS AbstractText: Clinical data were collected from a European database of patients with epilepsy.
Neurological and Central Nervous System Diseases (4) Seizures (3), Sclerosis (2), Epilepsy (2), more mentions
Neuroimaging studies of malformations of cortical development have mainly focused on the characterization of the primary lesional substrate, while whole-brain investigations remain scarce. Our purpose was to assess large-scale brain organization in prevalent cortical malformations. Based on experimental evidence suggesting that distributed effects of focal insults are modulated by stages of brain development, we postulated differential patterns of network anomalies across subtypes of malformations. We studied a cohort of patients with focal cortical dysplasia type II (n = 63), subcortical nodular heterotopia (n = 44), and polymicrogyria (n = 34), and compared them to 82 age- and sex-matched controls. Graph theoretical analysis of structural covariance networks indicated a consistent rearrangement towards a regularized architecture characterized by increased path length and clustering, as well as disrupted rich-club topology, overall suggestive of inefficient global and excessive local connectivity. Notably, we observed a gradual shift in network reconfigurations across subgroups, with only subtle changes in focal cortical dysplasia type II, moderate effects in heterotopia and maximal effects in polymicrogyria. Analysis of resting state functional connectivity also revealed gradual network changes, with most marked rearrangement in polymicrogyria; contrary to findings in the structural domain, however, functional architecture was characterized by decreases in both local and global parameters. Diverging results in the structural and functional domain were supported by formal structure-function coupling analysis. Our findings support the concept that time of insult during corticogenesis impacts the severity of topological network reconfiguration. Specifically, late-stage malformations, typified by polymicrogyria, may selectively disrupt the formation of large-scale cortico-cortical networks and thus lead to a more profound impact on whole-brain organization than early stage disturbances of predominantly radial migration patterns observed in cortical dysplasia type II, which likely affect a relatively confined cortical territory.
Polymicrogyria (4), Cortical Dysplasia (3), Malformations of Cortical Development (2), more mentions
The more inclusive grouping of neurological disorders included stroke, meningitis, encephalitis, tetanus, Alzheimer's disease and other dementias, Parkinson's disease, epilepsy, multiple sclerosis, motor neuron disease, migraine, tension-type headache, medication overuse headache, brain and nervous system cancers, and a residual category of other neurological disorders. We also analysed results based on the Socio-demographic Index (SDI), a compound measure of ...
Neurological and Central Nervous System Diseases (2), Neuroscience (2), Pain Management (2) Nervous System Diseases (15), Stroke (4), Tension-Type Headache (2), more mentions