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Brain Trauma
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Head injury is the most common cause of neurologic illness in young people. The overall incidence of traumatic brain injury in the US is approximately 550/100,000 - approximately 2 million per year. Two-thirds of TBIs are considered "mild", whereas 20% are severe and 10% are fatal. Rate of TBI are highest in the very young, adolescents, and the elderly. From the Washington Manual of Medical Therapeutics, 35e

Your search returned 34 results
from the time period: last 30 days.
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The Journal of head trauma rehabilitation
... demonstrate that a subpopulation of patients with mild/moderate traumatic brain injury (TBI) had intracranial pathology despite having a Glasgow Coma Scale ... All causes of CT+ brain injury were present in both SAC groups AbstractText: A normal GCS ... a SAC score do not exclude the possibility of significant intracranial injury.
Men's Health (2)
Traumatic Brain Injuries (3), Craniocerebral Trauma (1), Coma (1), more mentions
Frontiers in human neuroscience 
Abstract: Background: Recent clinical studies in stroke and traumatic brain injury (TBI) victims suffering chronic neurological injury present evidence that hyperbaric oxygen therapy (HBOT) can induce neuroplasticity. Objective: To assess the neurotherapeutic effect of HBOT on prolonged post-concussion syndrome (PPCS) due to TBI, using brain microstructure imaging. Methods: Fifteen patients afflicted with PPCS were treated with 60 daily HBOT ...
Cardiovascular Diseases (1)
Traumatic Brain Injuries (5), Post-Concussion Syndrome (1), Stroke (1), more mentions
Neurology
AbstractText: To comprehensively assess recurrent traumatic brain injury (rTBI) risk and risk factors in the general population AbstractText: We systematically searched MEDLINE, EMBASE, and ... Risk factors measured at time of index traumatic brain injury (TBI) that were significantly associated with rTBI in more than one study were male sex, prior ...
Neurological and Central Nervous System Diseases (1)
Traumatic Brain Injuries (7), Epilepsy (1), more mentions
American journal of surgery
... to be un-helmeted (p < 0.001) and to have a traumatic brain injury (p < 0.001... universal helmet law, there has been a significant increase in traumatic brain injuries and neurosurgical interventions... universal helmet law, there has been a significant increase in traumatic brain injuries and neurosurgical interventions... Keyword: Traumatic brain injury.
Traumatic Brain Injuries (5), more mentions
Anesthesiology
Bias increased significantly with increasing oxygen extraction (P < 0.0001) AbstractText: Changes in PaCO2 affect cerebral oximeter accuracy, and increased bias occurs with hypocapnia. Decreased accuracy may represent an incorrect assumption of a static arterial-venous blood fraction. Understanding cerebral oximetry limitations is especially important in patients at risk for hypoxia-induced brain injury, where PaCO2 may be purposefully altered.
Hypocapnia (5), Hypoxia (1), Brain Injuries (1), more mentions
JAMA neurology 
Cortical thickness and subcortical volumes were smaller in HIV-positive individuals compared with controls. However, changes in brain volume over time were similar between the groups AbstractText: These findings are consistent with the idea that cognitive and structural brain changes may occur early after seroconversion, and argue that maintaining aviremia with cART can prevent or minimize progressive brain injury.
Immune System Diseases (16)
Infections (2), Communicable Diseases (1), Brain Injuries (1), more mentions
7. Airway Management in Trauma.  
Date: 11/14/2017
Emergency medicine clinics of North America 
Airway management strategies for the care of the polytrauma patient are reviewed, with specific considerations for those presenting with traumatic brain injury, suspected c-spine injury, the contaminated airway, the agitated trauma patient, maxillofacial trauma, and the traumatized airway. An approach to airway management that considers the potential anatomic and physiologic challenges in caring for these complicated trauma patients is ...
Traumatic Brain Injuries (1), more mentions
PLoS computational biology 
Multiple Sclerosis (MS) is an autoimmune disease driving inflammatory and degenerative processes that damage the central nervous system (CNS). However, it is not well understood how these events interact and evolve to evoke such a highly dynamic and heterogeneous disease. We established a hypothesis whereby the variability in the course of MS is driven by the very same pathogenic mechanisms responsible for the disease, the autoimmune attack on the CNS that leads to chronic inflammation, neuroaxonal degeneration and remyelination. We propose that each of these processes acts more or less severely and at different times in each of the clinical subgroups. To test this hypothesis, we developed a mathematical model that was constrained by experimental data (the expanded disability status scale [EDSS] time series) obtained from a retrospective longitudinal cohort of 66 MS patients with a long-term follow-up (up to 20 years). Moreover, we validated this model in a second prospective cohort of 120 MS patients with a three-year follow-up, for which EDSS data and brain volume time series were available. The clinical heterogeneity in the datasets was reduced by grouping the EDSS time series using an unsupervised clustering analysis. We found that by adjusting certain parameters, albeit within their biological range, the mathematical model reproduced the different disease courses, supporting the dynamic CNS damage hypothesis to explain MS heterogeneity. Our analysis suggests that the irreversible axon degeneration produced in the early stages of progressive MS is mainly due to the higher rate of myelinated axon degeneration, coupled to the lower capacity for remyelination. However, and in agreement with recent pathological studies, degeneration of chronically demyelinated axons is not a key feature that distinguishes this phenotype. Moreover, the model reveals that lower rates of axon degeneration and more rapid remyelination make relapsing MS more resilient than the progressive subtype. Therefore, our results support the hypothesis of a common pathogenesis for the different MS subtypes, even in the presence of genetic and environmental heterogeneity. Hence, MS can be considered as a single disease in which specific dynamics can provoke a variety of clinical outcomes in different patient groups. These results have important implications for the design of therapeutic interventions for MS at different stages of the disease.
Immune System Diseases (5)
Multiple Sclerosis (13), Autoimmune Diseases (1), more mentions
The Journal of head trauma rehabilitation
AbstractText: Examine effects of diagnostically relevant posttraumatic stress disorder (PTSD) symptoms, mild traumatic brain injury (TBI) severity, and associated bodily injury severity on postconcussion symptom reporting in female service members (SM) compared with a matched sample of male SM AbstractText: Six US military medical treatment facilities AbstractText: A total of ...
Post-Traumatic Stress Disorders (10), Traumatic Brain Injuries (9), Unconsciousness (1), more mentions
Brain injury 
... evaluates its role in facilitating interdisciplinary team work for the care of people with a traumatic brain injury (TBI) AbstractText: Systematic review AbstractText: Studies were identified by searching CINAHL, Embase, Medline, PsycINFO, Scopus, and ... barriers and enablers which characterize a successful interdisciplinary eHealth model for people with TBI Keyword: Traumatic brain injury.
Traumatic Brain Injuries (7), more mentions
The Journal of head trauma rehabilitation
AbstractText: To examine the associations between lifetime history of traumatic brain injury (TBI) with loss of consciousness (LOC) and several types of current disability among adult, noninstitutionalized residents of Ohio AbstractText: 2014 Ohio Behavioral Risk Factors Surveillance System participants (n = 6998) AbstractText: Statewide population-based survey AbstractText: Lifetime history of ...
Neuroscience (1)
Traumatic Brain Injuries (9), Unconsciousness (1), more mentions
The Journal of head trauma rehabilitation
AbstractText: To identify preinjury variables related to mental health treatment utilization at 2 years post-traumatic brain injury (TBI) AbstractText: Veterans Affairs (VA) TBI Model Systems includes 5 VA Polytrauma Rehabilitation Centers AbstractText: Veterans and service members enrolled in TBI Model Systems who completed the year 2 follow-up assessment ...
Neuroscience (1)
Traumatic Brain Injuries (7), more mentions
The Lancet. Neurology 
Traumatic brain injury: a global challenge..
Traumatic Brain Injuries (2), more mentions
The Lancet. Neurology 
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research..
Traumatic Brain Injuries (2), more mentions
The Journal of head trauma rehabilitation
AbstractText: To investigate the use of a robotic assessment tool to quantify sensorimotor, visuospatial attention, and executive function impairments in individuals with traumatic brain injury (TBI) AbstractText: Foothills Hospital (Calgary, Canada) AbstractText: Twenty-three subjects with first-time TBI in the subacute to chronic phase participated in this study. Normative data were collected from 275 to 494 neurologically intact control ...
Traumatic Brain Injuries (9), more mentions
The Journal of head trauma rehabilitation
AbstractText: To identify and appraise studies evaluating the efficacy of telerehabilitation for adults with traumatic brain injury (TBI) AbstractText: A systematic search of Cochrane Library, MEDLINE, CINAHL (Cumulative Index to Nursing and Allied Health Literature), and PsycINFO databases was conducted from January 1980 to April 23, 2017, for studies evaluating ...
Traumatic Brain Injuries (5), more mentions
The Journal of head trauma rehabilitation
AbstractText: To evaluate the efficacy of a psychological intervention to reduce moderate to severe hopelessness among Veterans with moderate to severe traumatic brain injury (TBI) AbstractText: Two-arm parallel group, controlled, randomized crossover trial, with 3-month follow-up for those initially allocated to treatment. Participants were randomly allocated in blocks of 4 on a 1:1 ratio to treatment ...
Neuroscience (2)
Traumatic Brain Injuries (5), more mentions
The Lancet. Neurology
Traumatic brain injury: a priority for public health policy..
Traumatic Brain Injuries (2), more mentions
Current opinion in neurology
Traumatic brain injury is a longitudinal disease process..
Traumatic Brain Injuries (2), more mentions
The Journal of head trauma rehabilitation
Mood Stabilizers for Traumatic Brain Injury-Related Agitation..
Traumatic Brain Injuries (2), more mentions
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