... have been detected by guideline-directed testing AbstractText: Of 1040 patients, the median age was 58 years (interquartile range, 50.5-66 years), 65.3% were male, and 81.3% had stage IV disease at the time of genomic analysis, with prostate, renal, pancreatic, breast, and colon cancer as the most common diagnoses.
Oncology (12) Neoplasms (20), Colonic Neoplasms (1), more mentions
... epirubicin (Epi) and the CSC inhibitor staurosporine (STS) to treat breasttumors, particularly when tumors relapsed after chemotherapy... demonstrated potent therapeutic efficacy against both naïve orthotopic 4T1-luc breasttumors and their recurrent Epi-resistant counterparts, significantly prolonging survival... Epi/m as a promising strategy for effective management of breastcancer Keyword: Breastcancer.
AbstractText: The increasing use of autologous fat grafting in breastcancer patients has raised concerns regarding its oncologic safety. This study evaluated patient outcomes and tumor recurrence following mastectomy reconstruction and autologous fat grafting AbstractText: Retrospective chart review identified patients who underwent mastectomy followed by breast reconstruction from 2010 to 2015.
Oncology (3), Cardiovascular Diseases (1), Endocrine Disorders (1) Neoplasms (2), Breast Neoplasms (2), Hypertension (1), more mentions
Patients and Methods We performed a phase I study of oral Z-endoxifen to determine its toxicities, maximum tolerated dose (MTD), pharmacokinetics, and clinical activity. Eligibility included endocrine-refractory, estrogen receptor-positive metastatic breastcancer... Conclusion In endocrine-refractory metastatic breastcancer, Z-endoxifen provides substantial drug exposure unaffected by CYP2D6 metabolism, acceptable toxicity, and promising antitumor activity.
Oncology (3) Neoplasms (3), Breast Neoplasms (3), Embolus (1), more mentions
However, Sox10 also labels primary breastcarcinomas, particularly those with the basal-like, triple negative phenotype. However, the utility of Sox10 labeling in metastatic breastcarcinomas has not been reported. Here, we prospectively evaluated Sox10 labeling in surgically resected metastatic breastcarcinomas from 26 patients sampled on tissue microarrays... this cohort, Sox10 labeling was seen in 3 (12%) metastatic breastcarcinomas, all of which were grade III, triple negative ductal carcinomas ...
Oncology (2) Carcinoma (14), Melanoma (2), Neoplasms (2), more mentions
Abstract: Breastcancer is the most frequent type of nonskin malignancy among women ... Recurrence and other pathologic situations are still an issue in breastcancer patients due to side effects, toxicity of drugs in normal ... From this point of view, breastcancer therapy and adjuvant methods represent a promising and challenging field ...
Abstract: The 15th St. Gallen International BreastCancer Conference 2017 in Vienna, Austria reviewed substantial new evidence on loco-regional and systemic therapies for early breastcancer ... in HER2 positive and triple-negative, stage II and III breastcancer... permit avoidance of chemotherapy in many patients with ER positive breastcancer.
Oncology (10) Breast Neoplasms (8), Neoplasms (5), Residual Neoplasm (1), more mentions
AbstractText: African American breastcancer patients have lower frequency of hormone receptor-positive (HR+)/human ... AbstractText: Using data and biospecimens from the population-based Carolina BreastCancer Study (CBCS) Phase 3 (2008-2013), we classified 980 invasive breastcancers using RNA expression-based PAM50 subtype and recurrence (ROR) score ... ages had a statistically significantly lower frequency of Luminal A breastcancer (25.4% and 33.6% in blacks vs 42.8% and 52.1% in ...
... immune infiltration for ER+ disease is not well defined AbstractText: Quantitative immune scores of cell abundance and spatial heterogeneity were computed using a fully automated hematoxylin and eosin-stained image analysis algorithm and spatial statistics for 1178 postmenopausal patients with ER+ breastcancer treated with five years' tamoxifen or anastrozole.
A small but statistically significant shift was found toward early-stage diagnosis for colorectal, lung, female breast, and pancreatic cancer and melanoma in patients who resided in expansion states. Conclusion Percent uninsured among nonelderly patients with newly diagnosed cancer declined substantially after the ACA, especially among low-income people who resided in Medicaid expansion states.
We investigated breastcancer patient preference on exercise programming in a prospective manner and ... Sixty-seven newly diagnosed breastcancer patients responded to questions regarding exercise programming related to cancer ... Additionally, a retrospective chart review was conducted on 500 random breastcancer patients... current recommendations for exercise could be to integrate exercise into breastcancer care earlier in treatment Keyword: Anthracycline.
... empirically, improves survival of women with early-stage, HER2-positive breastcancer but also adds substantially to cost, toxicity, and inconvenience... year versus shorter durations of trastuzumab in adjuvant treatment of breastcancer... disease-free survivals in women with early-stage HER2 positive breastcancer compared to shorter durations and this should remain as the ...
AbstractText: Non-adherence to tamoxifen is common in breastcancer survivors and is associated with poor clinical outcomes... with non-adherence AbstractText: A qualitative study using semi-structured interviews AbstractText: Thirty-two breastcancer survivors who had been prescribed tamoxifen took part in interviews conducted face to face ... Keyword: breastcancer.
The most common cancers associated with an ED visit were breast, prostate, and lung cancer, and most common primary reasons for visit were pneumonia (4.5 ... inpatient admission AbstractText: Consistent with national prevalence statistics among adults, breast, prostate, and lung cancer were the most common cancer diagnoses presenting to the ED ...
Oncology (18), Men's Health (16), Urology (1) Neoplasms (16), Lung Neoplasms (2), Pneumonia (2), more mentions
We present a first demonstration of this concept for parallelized imaging by synthesizing two light-sheets with nonlinear Bessel beams and perform volumetric imaging of fluorescent beads and invasive breastcancer cells. This work demonstrates that in principle any digitally scanned LSFM can be parallelized in a lossless manner, enabling drastically faster volumetric image acquisition rates for a given sample ...