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Gynecologic Cancer
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Your search returned 24 results
from the time period: last 30 days.
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Clinical cancer research : an official journal of the American Association for Cancer Research
Expansion cohorts of approximately 20 patients each explored AZD5363 activity in PIK3CA-mutant breast and gynecologic cancers AbstractText: Maximum tolerated doses were 320 mg, 480 mg and 640 mg for continuous (n=47), 4/7 (n=21) and 2/7 (n=22) schedules, respectively. Dose-limiting toxicities were rash and diarrhea for continuous, hyperglycemia for 2/7, and none for ...
Neoplasms (3), Hyperglycemia (2), Diarrhea (2), more mentions
Annals of surgical oncology
This study aimed to assess quality of life (QOL) during the first year after pelvic exenteration for gynecologic malignancy performed with curative intent AbstractText: A French multicentric prospective study was performed by including patients who underwent pelvic exenteration. Quality of life by measurement of functional and symptom scales was assessed using the European Organisation for Research and Treatment of Cancer ...
Oncology (1)
Anorexia (2), Dyspnea (1), Neoplasms (1), more mentions
The Journal of clinical investigation
UBB is repressed in approximately 30% of high-grade serous ovarian cancer (HGSOC) patients and is a recurrent lesion in uterine carcinosarcoma and endometrial carcinoma ... We identified ovarian tumor cell lines that retain UBB in a repressed state, used these cell lines to establish orthotopic ovarian tumors, and found that inducible expression of a UBC-targeting shRNA ...
Oncology (4)
Neoplasms (5), Ovarian Neoplasms (2), Endometrial Carcinoma (1), more mentions
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 
Here, we present the results from the cohort of patients with advanced cervical cancer... Results Twenty-four patients were enrolled in the cervical cancer cohort... Conclusion In patients with programmed death ligand 1-positive advanced cervical cancer, pembrolizumab demonstrated antitumor activity and exhibited a safety profile consistent with that seen ...
Oncology (4)
Uterine Cervical Neoplasms (4), Neoplasms (3), more mentions
Obstetrics and gynecology
... initial and secondary management strategies for women with high-grade vaginal intraepithelial neoplasia AbstractText: We conducted a retrospective case series of women referred ... a single center for management of biopsy-proven, high-grade vaginal intraepithelial neoplasia between April 1994 and May 2016... Recurrence was defined as a biopsy showing any vaginal intraepithelial neoplasia diagnosis after primary treatment AbstractText: Forty-seven patients were treated ...
Neoplasms (5), Dyspareunia (1), more mentions
Proceedings of the National Academy of Sciences of the United States of America 
... enabled us to exhaustively characterize the immunopeptidomic landscape of epithelial ovarian cancers (EOCs... a variety of benign sources has unveiled a multitude of ovarian cancer antigens (MUC16, MSLN, LGALS1, IDO1, KLK10) to be presented by HLA class I and class II molecules exclusively on ovarian cancer cells ... Keyword: ovarian cancer.
Oncology (5)
Ovarian Neoplasms (3), Neoplasms (2), Carcinoma (1), more mentions
Nature communications 
Abstract: High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of ovarian cancer and has a poor outcome ... analyses reveal that p53 signatures and STICs are precursors of ovarian carcinoma and identify a window of 7 years between development of a STIC and initiation of ovarian carcinoma, with metastases following rapidly thereafter ...
Oncology (2)
Carcinoma (5), Ovarian Neoplasms (2), Neoplasms (1), more mentions
Annals of surgical oncology
AbstractText: Initial experiences reported increased surgical morbidities in patients receiving cytoreductive surgery for colorectal cancer after bevacizumab-containing chemotherapy; however, more recent literature suggests a favorable toxicity profile in patients with advanced ovarian cancer (AOC. With the aim of providing a more objective point of view on this controversial issue, we present here a systematic literature review AbstractText: Systematic revision ...
Oncology (3)
Ovarian Neoplasms (2), Colorectal Neoplasms (1), more mentions
Journal of the National Cancer Institute
Abstract: With recent ovarian cancer screening studies showing no clinically significant mortality benefit, preventing this ... However, several challenges are impeding progress in ovarian cancer research... oral contraceptive formulations and increased intrauterine device use, might influence ovarian cancer risk and survival is difficult. Risk factors for ovarian cancer should be evaluated in the context of tumor histotypes, which ...
Oncology (6)
Ovarian Neoplasms (6), Neoplasms (2), more mentions
International journal of cancer 
During a median follow up of 11.5 years, 2,598 cases of prostate cancer (including 287 advanced cases) have been identified among 27,004 men in the intervention arm of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Dietary intake of phytoestrogens (excluding lignans) was assessed with a food frequency questionnaire.
Oncology (11)
Prostatic Neoplasms (8), Ovarian Neoplasms (2), Neoplasms (1), more mentions
Obstetrics and gynecology 
... of care during the first year after a diagnosis of ovarian cancer, estimate the sources of cost, and explore the out-of ... AbstractText: We performed a retrospective cohort study of women with ovarian cancer diagnosed from 2009 to 2012 who underwent both surgery and ... cost of care within the first year of diagnosis of ovarian cancer; secondary outcomes included assessment of factors associated with cost AbstractText: A total of 26,548 women with ovarian cancer who underwent surgery were identified ...
Oncology (6)
Ovarian Neoplasms (6), more mentions
Clinical cancer research : an official journal of the American Association for Cancer Research 
... adjusted HR, 0.30; 95% CI, 0.13-0.68; p=0.004) and 5-year OS (78%; adjusted HR, 0.09; 95% CI, 0.02-0.38; p=0.001) AbstractText: Among ovarian cancer patients, BRCA2 carriers with mutations located in the RAD51-BD (exon 11) have prolonged progression-free survival, platinum-free interval and overall survival.
Oncology (3)
Ovarian Neoplasms (2), Neoplasms (1), more mentions
eLife 
Abstract: Recent studies posit a role for non-coding RNAs in epithelial ovarian cancer (EOC... 454 patients with various diagnoses, the miRNA neural network had 100% specificity for ovarian cancer... suggest circulating miRNAs have potential to develop a non-invasive diagnostic test for ovarian cancer Keyword: cancer biology... Keyword: ovarian cancer.
Oncology (6)
Ovarian Neoplasms (5), Neoplasms (1), more mentions
Clinical cancer research : an official journal of the American Association for Cancer Research
AbstractText: Women with epithelial ovarian cancer generally have a poor prognosis, however a subset of patients has ... grade serous cancer (HGSC), a disease associated with the majority of ovarian cancer deaths AbstractText: We evaluated the histories of 2,283 ovarian cancer patients and, after applying stringent clinical, and pathological selection criteria, identified ...
Oncology (5)
Ovarian Neoplasms (4), Neoplasms (3), Retinoblastoma (1), more mentions
The Lancet. Oncology
Possible origin of ovarian cancer in the fallopian tubes..
Oncology (2)
Ovarian Neoplasms (2), more mentions
Annals of surgical oncology
Comment on: Surgery and HIPEC in Recurrent Epithelial Ovarian Cancer: A Prospective Randomized Phase III Study..
Oncology (2)
Ovarian Neoplasms (2), more mentions
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Maintenance Poly (ADP-ribose) Polymerase Inhibitor Therapy for Ovarian Cancer: Precision Oncology or One Size Fits All?.
Oncology (4)
Ovarian Neoplasms (2), more mentions
Emerging infectious diseases
Abstract: Cervical cancer incidence and mortality rates are high, particularly in developing countries. Most cervical cancers can be prevented by human papillomavirus (HPV) vaccination, screening, and timely ... CDC collaborates with global partners to develop global cervical cancer screening recommendations and manuals, implement screening, create standardized evaluation tools, and ... Keyword: cervical cancer.
Oncology (8), Vaccines (1)
Uterine Cervical Neoplasms (4), Neoplasms (4), Infections (1), more mentions
Obstetrics and gynecology 
... between use of an intrauterine device (IUD) and risk of cervical cancer by subjecting existing data to critical review, quantitative synthesis, and ... individual-level measures of use of an IUD and incident cervical cancer... protective effect, which may be stronger in populations with higher cervical cancer incidence AbstractText: Invasive cervical cancer may be approximately one third less frequent in women who ...
Oncology (9)
Uterine Cervical Neoplasms (9), more mentions
JAMA oncology 
Trends in Breast, Colorectal, and Cervical Cancer Incidence Following the Affordable Care Act: Implications for Cancer Screening..
Oncology (4)
Uterine Cervical Neoplasms (2), Neoplasms (2), more mentions
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